Diagnostic concordance between bone marrow aspirate and trephine biopsy in hematological neoplasms and non-hematological marrow infiltrations [0.03%]
骨髓穿刺与活检在血液系统肿瘤及非血液系统骨髓浸润性病变中的诊断一致性分析
Esmat A El-Sharkawy,Eman Mosad,Nagwa I Okaily et al.
Esmat A El-Sharkawy et al.
Evaluating concurrent bone marrow aspirate (BMA) and trephine biopsy (BMB) specimens demonstrates significant diagnostic complementarity, reducing false-negative rates in plasma cell dyscrasias and marrow infiltrations, and proving that com...
On the current clinical applicability of artificial intelligence in pathology: An evidence-informed clinical readiness review [0.03%]
基于证据的临床准备性评估：人工智能在病理学领域的当前临床应用能力分析
Alberto M Marchevsky,Ann E Walts
Alberto M Marchevsky
The integration of artificial intelligence (AI) into pathology practice is anticipated to drive substantial advancements. Numerous AI-based applications have been reported but the extent of their current clinical applicability remains uncer...
Determinants of nucleic acid quality in formalin-fixed paraffin-embedded bladder urothelial carcinoma specimens: effects of specimen type, fixation conditions, and storage time [0.03%]
影响甲醛固定石蜡包埋膀胱尿路上皮癌标本中核酸质量的因素：标本类型、固定条件和储存时间的影响
Shu Yuguchi,Yoichiro Okubo,Rika Kasajima et al.
Shu Yuguchi et al.
Formalin-fixed paraffin-embedded (FFPE) tissue is the principal substrate for cancer genomic profiling, yet pre-analytical factors affect nucleic acid quality. In our workflow, transurethral resection (TUR) specimens of bladder urothelial c...
Penile median raphe cysts: A multicenter retrospective clinicopathological and immunohistochemical study [0.03%]
阴茎正中沟囊肿的临床病理和免疫组化特征分析多中心回顾性研究
Yishun Huang,Lixin Wang,Feng Xu et al.
Yishun Huang et al.
To investigate the clinical, histopathological, and immunohistochemical features of penile median raphe cysts and to further characterize their epithelial phenotypes and possible histogenesis. We performed a multicenter retrospective analys...
Development and clinical application of a histopathology-based pathological scoring system for IgG4-related disease [0.03%]
基于组织病理学的IgG4相关性疾病病理评分系统及其临床应用研究
Huimin Ni,Yao Xu,Guoxiang Xu et al.
Huimin Ni et al.
IgG4-related disease (IgG4-RD) diagnosis remains challenging due to subjective histopathological interpretation. This study aimed to develop and internally evaluate a quantitative pathological scoring system to improve diagnostic accuracy. ...
Improved prostate cancer grading by incorporating Gleason pattern quantification, invasive cribriform and intraductal carcinoma in the new QUICC-score [0.03%]
通过在新的QUICC评分中结合GLEASON分级量化、侵袭性筛状和小叶内癌来改进前列腺癌的分级
Lisa J Kroon,Cláudia Cruz Oliveira,Eva Hollemans et al.
Lisa J Kroon et al.
Pathological Gleason grading is the cornerstone of risk assessment in prostate cancer (PCa) patients. Detailed Gleason pattern (GP) quantification and presence of invasive cribriform and intraductal carcinoma (CR/IDC) have recently been rec...
The long-term postoperative course of an intraosseous spindle cell hemangioma of the calcaneus [0.03%]
跟骨骨内梭形细胞血管瘤的术后长期随访
Michiyuki Hakozaki,Shoki Yamada,Yoichi Kaneuchi
Michiyuki Hakozaki
Myoepithelioma-like tumor of the vulvar region shows a quiet genome and heterogeneous detectable mechanisms of SMARCB1 inactivation: Integrated analysis of two cases and review of the literature [0.03%]
静默基因组和异质性SMARCB1失活机制的阴部肌上皮瘤样肿瘤：两例综合分析及文献回顾
Hiroshi Yoshida,Mayumi Kobayashi-Kato,Kouya Shiraishi et al.
Hiroshi Yoshida et al.
Myoepithelioma-like tumor of the vulvar region (MELTVR) is a rare SMARCB1-deficient mesenchymal neoplasm of adult women that can mimic malignant vulvar sarcomas, particularly epithelioid sarcoma. Although loss of SMARCB1/INI1 expression is ...
Re-evaluation of "Peptic" duodenitis: A review of 622 consecutive duodenal biopsies [0.03%]
对“十二指肠炎”的再评价：622例连续十二指肠活检的回顾分析
Mohamed E Mostafa,Christopher P Hartley,Catherine E Hagen
Mohamed E Mostafa
"Peptic" duodenitis, classically attributed to peptic injury including Helicobacter pylori infection, comprises foveolar (gastric) metaplasia of the surface duodenal epithelium and Brunner gland hyperplasia. Despite a declining prevalence o...
Unusual morphologic features in molecularly defined high-grade sarcomas of the uterus [0.03%]
分子定义的子宫高级别肉瘤的异常形态学特征
Khadijah Abdulhaleem,Allen W Zhang,Tony Ng et al.
Khadijah Abdulhaleem et al.
Herein we describe unusual or rare morphologic features in two high-grade uterine sarcomas with novel or uncommon genetic alterations, to bring attention to their morphologic diversity, diagnostic challenges, and potential therapeutic impli...