Diagnostic accuracy of nuclear STAT6 immunohistochemistry for solitary fibrous tumour: a systematic review and meta-analysis [0.03%]
核STAT6免疫组化诊断孤立性纤维瘤准确性的系统评价和meta分析
Vishal Tayade,Gyanendra Singh
Vishal Tayade
Nuclear STAT6 immunohistochemistry is the diagnostic surrogate for the NAB2::STAT6 fusion of solitary fibrous tumour (SFT); its sensitivity is established, but specificity varies for unexamined reasons. This review quantified pooled accurac...
Diagnostic specificity of the novel marker TRPS1 compared with traditional breast-specific markers in differentiating metastatic breast carcinoma from adrenal neoplasms [0.03%]
新型标记物TRPS1与传统乳腺标记物在鉴别转移性乳腺癌和肾上腺原发肿瘤中的诊断特异性比较研究
Anandi Lobo,Douglas J Wu,Ankur R Sangoi
Anandi Lobo
Trichorhinophalangeal syndrome type 1 (TRPS1), a novel GATA transcription factor, has emerged as a sensitive and largely breast-specific marker across various carcinoma subtypes, including metastatic tumors. However, its specificity in adre...
The application value of serous cavity effusion supernatant in multi-driver gene detection for non-small cell lung cancer [0.03%]
非小细胞肺癌多驱动基因检测的体液诊断价值评估：胸腹水标本超敏NGS检测结果分析
Lvli Dong,Yaqian Cao,Ying Liu et al.
Lvli Dong et al.
Obtaining tissue from advanced non-small cell lung cancer(NSCLC) patients is difficult, yet mutation testing is crucial for targeted therapy. This study evaluates the clinical utility of serous cavity effusion (SCE) supernatant for multi-ge...
Combined immunohistochemical analyses of p16 and β-catenin in solitary fibrous tumors (SFT) might define different biological subgroups [0.03%]
p16和β-catenin联合免疫组化分析可将孤立性纤维瘤(SFT)分成不同的生物学亚群
M Forberger,M Steinert,S Krämer et al.
M Forberger et al.
Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms with variable clinical behavior, ranging from indolent to aggressive. Immunohistochemical data regarding p16 and ß-catenin are conflicting, a direct comparative analysis of both...
Distinguishing EBV-positive classic Hodgkin lymphoma from EBV-positive DLBCL, NOS: diagnostic value and limits of immunohistochemical markers [0.03%]
EB病毒阳性经典型霍奇金淋巴瘤与EB病毒阳性DLBCL，NOS的鉴别诊断——免疫组化标记物的价值和限度
Vets Johanna,Vivian Lisa Francesca,Marcelis Lukas et al.
Vets Johanna et al.
Epstein-Barr virus-positive (EBV+) classic Hodgkin lymphoma (cHL) may mimic EBV+ diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS), creating a clinically relevant diagnostic pitfall. We retrospectively reviewed 62 immunoco...
Predicting HER2 amplification in breast cancers with equivocal HER2 immunohistochemistry [0.03%]
预测HER2免疫组化结果不确定的乳腺癌中的HER2基因扩增
Jennifer Den,Efstathia Polychronopoulou,Caroline Baughn et al.
Jennifer Den et al.
Accurate determination of human epidermal growth factor receptor 2 (HER2) status is essential for guiding targeted therapy in breast cancer. Immunohistochemistry (IHC) is routinely used for initial screening. Although reflex FISH testing is...
Incidental thyroid tissue in cervical lymph nodes in patients with fibrosing variant of Hashimoto thyroiditis [0.03%]
桥本甲状腺炎纤维化变异型患者的颈部淋巴结内甲状腺组织 incidentalność甲状腺组织在纤维变体桥本氏甲状腺炎患者的颈部淋巴结中出现
Michel Kmeid,Akeesha A Shah,Daniel Mettman et al.
Michel Kmeid et al.
Bland thyroid follicles are occasionally identified within cervical lymph nodes, raising the differential diagnosis of benign thyroid inclusions versus metastatic papillary thyroid carcinoma. Proposed criteria for benign thyroid inclusions ...
From the archives of MD Anderson Cancer Center: Crystal-storing histiocytosis associated with B-cell lymphoma [0.03%]
M.D.安德森癌症中心档案室报道：晶体贮积组织细胞增生症与B细胞淋巴瘤有关
Omar Al-Rusan,Qi Shen,L Jeffrey Medeiros
Omar Al-Rusan
Crystal-storing histiocytosis (CSH) is rare morphologic manifestation of disease histologically characterized by benign histiocytes, usually numerous, filled with cytoplasmic eosinophilic crystals. More than 200 cases have been reported in ...
Granulomatous inflammation in lung and lymph node specimens: A molecularly enhanced pathology-based algorithm for etiologic differential diagnosis [0.03%]
基于病理学的分子算法在鉴别导致肺和淋巴结肉芽肿性炎症病因中的作用
Min Hong,Lupeng Ji,Jiong Gao et al.
Min Hong et al.
Granulomatous inflammation is frequently encountered in lung and lymph node specimens and represents a diagnostic challenge because diverse infectious, immune-mediated, exposure-related, and neoplastic conditions may produce overlapping his...
Primary biliary cholangitis: Beyond classical histopathology - diagnostic challenges in native and transplanted livers [0.03%]
原发性胆汁性胆管炎：经典组织病理学之外——自身和移植肝脏中的诊断挑战
Ivana Juskova,Andrea Vajsova,John Jackson et al.
Ivana Juskova et al.
Primary biliary cholangitis (PBC) is a chronic autoimmune cholestatic liver disease characterised by immune-mediated injury of small intrahepatic bile ducts, ultimately leading to progressive fibrosis, cirrhosis, and liver-related complicat...