Inhaled corticosteroids monotherapy in childhood asthma: Any differential response rate between activated and prodrugs? [0.03%]
儿童哮喘吸入皮质类固醇单药治疗：活性药物与前体药物的疗效差异？
Poly Majumder,Anna Smyrnova,Francine M Ducharme
Poly Majumder
Objective: The efficacy of inhaled corticosteroids (ICS) as prodrugs (inactive at delivery) has been compared to activated ICS, in mean changes in lung function and symptoms, with limited evidence on achieving control. We...
Eosinophilic vasculitis of aortic valve in EGPA: a life-threatening onset of disease [0.03%]
变应性肉芽肿血管炎伴主动脉瓣嗜酸性粒细胞浸润致急性主动脉瓣狭窄一场威胁生命的表现形式
Niccolò Paoletti,Leandro Cosco,Emanuele Vivarelli et al.
Niccolò Paoletti et al.
Objective: Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss Syndrome, is an anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis that can manifest with a wide spectrum o...
Revealing shared gene signatures and HIF-1α pathway in allergic rhinitis and asthma: a bioinformatics and experimental study [0.03%]
基于生物信息学和实验研究揭示过敏性鼻炎与哮喘共有的基因特征及HIF-1α信号通路
Zhuiyue Wang,Jing Chen,Yuanyuan Zhang et al.
Zhuiyue Wang et al.
Background: Allergic rhinitis (AR) and asthma (AS) are closely linked in both epidemiology and pathogenesis, though the mechanisms remain unclear. This study aims to identify shared gene signatures and molecular mechanism...
Circulating IL-6 Associates with a Distinct Pediatric Asthma Subtype and Serves as a Potential Key Predictor for Risk Stratification [0.03%]
循环IL-6与特定的儿童哮喘亚型相关并可作为潜在的关键风险分层预测因子
Yuyang Liu,Lina Cheng,Lu Wang
Yuyang Liu
BackgroundsChildhood asthma is a heterogeneous disease wherein systemic inflammation, particularly involving non-type 2 cytokines like interleukin-6 (IL-6), is not universally present and its clinical significance remains unclear. This cros...
Factors Affecting Length of Hospital Stay in Children with Moderate-to-Severe Asthma Exacerbations [0.03%]
中重度哮喘急性发作儿童住院时间的影响因素分析
Aymen Hişmioğullari,Özlem Sancakli,Soner Günder et al.
Aymen Hişmioğullari et al.
Background: Hospitalizations due to moderate to severe asthma exacerbations in children present significant challenges for health systems and families. Identifying factors affecting duration of hospitalization (DOH) is cr...
Risk factors, preventive strategies, and long-term effects of lower respiratory tract infections in early childhood: a comprehensive review [0.03%]
儿童早期下呼吸道感染的危险因素、预防策略和长期影响：全面综述
Arul Kiruba N M,Mary Minolin T,Mary Nithya P
Arul Kiruba N M
Objective: To synthesize existing evidence on the risk factors, preventive measures, and long-term outcomes of lower respiratory tract infections (LRTIs) in early childhood, and to identify key gaps in research and policy...
To the RESCUE: Program Fidelity and Experiences of an Illinois Stock Inhaler Program [0.03%]
拯救行动计划的忠实度和伊利诺斯州股票吸入器计划的经验教训分析研究
Paige Hardy,Anna Volerman,Alexandra Knitter et al.
Paige Hardy et al.
Objective: The Resources for Schools Encountering Unexpected Asthma Emergencies-Illinois (RESCUE-IL) program-which provides stock inhalers, materials, and training-expanded to all Illinois public schools in its second yea...
Suayip Ceylan,Ahmet Cagın,Onur Ozturk
Suayip Ceylan
Objective: This study evaluated sexual function in patients with asthma and its association with sociodemographic and clinical factors. Methods: ...
Mid-term impact of COVID-19 related non-pharmaceutical interventions on the incidence of hospitalizations for severe asthma exacerbation in children: a ten-year time-series analysis [0.03%]
基于新冠相关非药物干预措施的中期效果对儿童严重哮喘住院率的影响：一项十年时间序列分析
Marie Facy,Zein Assad,Zaba Valtuille et al.
Marie Facy et al.
Background: The aim of this study was to analyze the temporal association of the national incidence of severe asthma exacerbations (SAEs) in children with the implementation and lifting of NPIs. ...
Child Asthma and Parental Mental Health: Exploring Associations by Parental Sex [0.03%]
父母的心理健康与儿童哮喘：按父母性别划分的关系探讨
Benjamin Zablotsky,Laryssa Mykyta,Jonaki Bose et al.
Benjamin Zablotsky et al.
Objective: Childhood asthma is a chronic condition that can be controlled with treatment. However, parents of children with asthma may face stressors such as juggling work and asthma care responsibilities, including the u...