A Novel Biomarker for Tiny Breaths: Linking Pulmonary Impedance, Wheeze Phenotypes and Atopy in Preschoolers [0.03%]
preschool儿童肺阻抗、哮鸣音表型和特应性的关系：一种新型生物标志物——微型呼吸信号
Gulten Tuncerler,Simge Atar Bese,Duygu Erge et al.
Gulten Tuncerler et al.
Background: Pentraxin-3 (PTX-3) is a humoral pattern recognition receptor involved in innate immunity and inflammation regulation, but its relationship with lung function remains unclear. ...
Extended nitric oxide analysis in patients with suspected airway hyperreactivity [0.03%]
怀疑气道高反应性患者硝酸氧化物的扩大分析方法
Giovanni Paoletti,Giovanni Costanzo,Marta Casini et al.
Giovanni Paoletti et al.
Objectives: a key feature of asthma is airway hyperresponsiveness (AHR), which is typically diagnosed through methacholine challenge testing (MCT). Fractional exhaled nitric oxide (FENO) is a non-invasive marker of type-2...
Parental Numeracy Skills and Pediatric Asthma Outcomes in Jordan: A Cross-Sectional Study of Asthma-Related Quality of Life [0.03%]
约旦父母的算术技能与哮喘结局：一项关于哮喘相关生活质量的横断面研究
Walid Al-Qerem,Anan Jarab,Abdel Qader Al Bawab et al.
Walid Al-Qerem et al.
Objective: Parental numeracy skills, reflecting a quantitative domain within health literacy, may be relevant to pediatric asthma management. However, the association between parental numeracy skills and the asthma-related quality of life (...
A mitochondria-related 9-gene induced sputum signature for severe asthma: an integrative transcriptomic analysis with external validation [0.03%]
与线粒体相关的严重哮喘诱导痰9基因标志物：整合转录组分析及外部验证
Ruonan Hui,Lecheng Zhang,Zhenliang Han et al.
Ruonan Hui et al.
Objective: Severe asthma is biologically heterogeneous, and airway-derived biomarkers for disease stratification remain limited. We aimed to identify a mitochondria-related induced sputum transcriptomic signature associat...
Smoking-Relapse Trajectories and Risk of Incident Asthma: Evidence From the 10-Year Korea Health Panel Survey (2009-2018) [0.03%]
基于2009-2018年韩国健康panel调查的复吸轨迹与新发哮喘风险的关系研究
Kyuhee Jo,Hyungkyun Mok
Kyuhee Jo
Background: Smoking relapse is prevalent, yet its long-term association with incident asthma remains underexplored. Repeated quit-relapse cycles may exacerbate airway inflammation more acutely than steady-state smoking. W...
Genetically predicted gut microbiota and risk of pediatric asthma and food allergy in East Asian populations: a two-sample Mendelian randomization study [0.03%]
东亚人群中遗传预测的肠道微生物群与儿童哮喘和食物过敏风险：两样本孟德尔随机化研究
Zaimeng Han,Caihong Zang,Chunjuan Zhang et al.
Zaimeng Han et al.
Objective: To investigate the genetically predicted associations between gut microbiota composition and the risk of pediatric asthma and food allergy in East Asian populations using a bidirectional two-sample Mendelian ra...
Beyond Biologics: Background Inhaled Therapy Shapes Remission in Severe Asthma [0.03%]
超越生物制剂：背景吸入疗法塑造重度哮喘的缓解过程
Vitaliano Nicola Quaranta,Giulia Amoroso,Alessio Marinelli et al.
Vitaliano Nicola Quaranta et al.
Background: Clinical remission has emerged as an achievable therapeutic goal in severe asthma treated with biologics. However, the potential influence of background inhaled therapy on remission outcomes remains insufficie...
Risk of Neuropsychiatric Adverse Events with Montelukast Combined with Inhaled Corticosteroids (ICS) in the Treatment of Asthma in Children and Adolescents: A Systematic Review and Meta-Analysis [0.03%]
montelukast联合吸入皮质类固醇治疗儿童及青少年哮喘增加神经精神不良事件风险的系统评价和.meta.分析
Qingming Yang,Cheng Guo,Xiaoli Yu et al.
Qingming Yang et al.
Background: Montelukast is widely used in pediatric asthma treatment, and concerns have been raised regarding its risk of neuropsychiatric adverse events (NEs). Existing studies predominantly focus on its monotherapy use,...
Feasibility and blinding validation of a sham bilevel positive airway pressure system in pediatric acute asthma [0.03%]
儿童急性哮喘患者使用伪无创双水平气道正压装置的可行性及盲法验证研究
Garret Lambert,Christopher Whelchel,Lanae Dailey et al.
Garret Lambert et al.
Objective: To develop a sham bilevel positive airway pressure (sBPAP) circuit to attenuate airway pressures, preserve blinding among clinicians and patients while assessing short term safety and feasibility. We hypothesiz...