Assessment of the impact of interferon-ß and rituximab on NLRP3 and AIM2 expression and IL-1β levels in patients with multiple sclerosis [0.03%]
干扰素-β和利妥昔单抗对NLRP3和AIM2表达及白细胞介素-1β水平的影响评估：多发性硬化患者中的研究
Sina Molavizade,Fereshteh Ashtari,Fateme Dehghani et al.
Sina Molavizade et al.
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. Inflammasomes, particularly NLRP3 and AIM2, have been implicated in MS pathogenesis. Interferon-β (IFN-β) and Rituximab (RTX) are treatment agents fo...
The role of SHMT2 and NDUFA4L2 gene expression and UCA1 levels in Egyptian patients with bladder cancer [0.03%]
SHMT2和NDUFA4L2基因表达及UCA1水平在埃及膀胱癌患者中的作用研究
Eman A E Badr,Yostena Mekhail,Khaled S A Hassan et al.
Eman A E Badr et al.
Bladder Cancer (BC) has a significant burden, with poor survival rates in advanced cases. This case-controlled study aimed to identify genes having diagnostic and prognostic value. Seventy patients with BC and 70 healthy individuals were in...
Single-chain variable fragment antibodies targeting the antileukemia agent harringtonine for enzyme-linked immunosorbent assay development [0.03%]
用于酶联免疫吸附测定开发的靶向抗白血病剂海萝汀的单链可变片段抗体
Seiichi Sakamoto,Shohei Komatsu,Ai Moriyasu et al.
Seiichi Sakamoto et al.
In this study, we generated a single-chain variable fragment (scFv) specific to a potent antileukemic substance, harringtonine (HT) (HT-scFv) that can be used in enzyme-linked immunosorbent assay (ELISA) for the quantitative analysis of HT ...
Occult hepatitis B and the detection of other HBV genes in HBs gene negative individuals in southwest Nigeria [0.03%]
尼日尔西南部 occult乙肝及HBs基因阴性个体中其他HBV基因的检出率
Olufisayo A Adesina,Favour A Babarinde,Dapo J Oluwajuyite et al.
Olufisayo A Adesina et al.
Considering the high tendency of hepatitis B virus (HBV) to mutate and escape diagnosis, and the high prevalence of its chronic infection in Nigeria, it is expedient to wholistically study the various genes to understand the changes and to ...
Seroprevalence and associated risk factors of Newcastle disease in guinea fowls in the Upper East region of Ghana [0.03%]
加纳上东部地区几内亚鸡新城疫的血清学流行率及其相关风险因素
Albert Agyapong Tweneboah,Sherry Ama Mawuko Johnson,Patrick Mensah Amponsah et al.
Albert Agyapong Tweneboah et al.
Newcastle Disease (ND) is a major constraint to poultry production in sub-Saharan Africa. However, information on Newcastle disease in guinea fowls is scant in Ghana. This study seeks to detect circulating antibodies against ND and the risk...
Implementation of TRAF3IP2 and SIGIRR gene polymorphisms and their expression levels in autoimmune thyroid diseases [0.03%]
TRAF3IP2和SIGIRR基因多态性及其表达水平在自身免疫性甲状腺疾病中的作用机制研究
Mona A Abbas,Raouth E Girgis,Hytham R Badr et al.
Mona A Abbas et al.
Genetics plays a crucial role in the development of autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's thyroiditis (HT). This study evaluated the relationship between TRAF3IP2 and SIGIRR gene expression, the...
Prognostic significance of B-Catenin and E-Cadherin expression in gastric carcinoma [0.03%]
胃癌中B-catenin和E-cadherin表达的预后意义分析
Sarra Ben Rejeb,Abir Labadi,Marwa Lakhal et al.
Sarra Ben Rejeb et al.
Introduction: Gastric cancer (GC) is a leading cause of cancer-related mortality worldwide. Dysregulation of molecular pathways, including β-Catenin-mediated Wnt signaling, epithelial-to-mesenchymal transition (EMT), and...
Costus speciosus extract: a natural immunomodulator for treatment of psoriasis in BALB/c mice by NF-κB pathway [0.03%]
-costus speciosus提取物通过NF-κB途径调节免疫系统治疗BALB/c小鼠银屑病的一种天然免疫调节剂
Aditi Vyas,Muqtada Shaikh,Radhika Raheja et al.
Aditi Vyas et al.
Psoriasis is a chronic inflammatory skin condition. Ayurveda, Traditional Chinese therapy, and Unani offer a potential approach to treating psoriasis. This study explores the immunomodulatory effects of Costus speciosus petroleum ether extr...
Immunohistochemical GATA3 expression in prostate adenocarcinoma: pitfalls [0.03%]
前列腺腺癌免疫组化GATA3表达的陷阱
Sarra Ben Rejeb,Yasmine Chaabane,Kalthoum Dridi et al.
Sarra Ben Rejeb et al.
Background: Recent studies have reported aberrant GATA3 immunohistochemical expression in high-grade prostate carcinoma, raising concerns about its specificity. This study aimed to evaluate GATA3 immunohistochemical expre...
Seroprevalence of H9N2 and H5 avian influenza in mixed-species poultry farms in Northern Benin [0.03%]
贝宁北部混养式养殖场家禽的H9N2和H5亚型禽流感血清学调查
Edmond Onidje,Oluwole Oyetunde Oni,Mireille Catherine Kadja et al.
Edmond Onidje et al.
Avian influenza is one of the major threats to poultry and human health in northern Benin, while mixed-species farming systems increase the risks of viral transmission. The present study estimated the seroprevalence of avian influenza subty...