Genetic association of Angiopoietin-2 rs12674822 and rs3739390 polymorphisms with systemic lupus erythematosus risk: a preliminary single-center study in Egyptian patients [0.03%]
Eman Abd Allah Fouda,Alshimaa M Elmalawany,Eman Masoud Abd El Gayed et al.
Eman Abd Allah Fouda et al.
Not applicable (observational study). Keywords: Angiopoietin-2; Egypt; Systemic lupus erythematosus; genetic...
Strategic analysis of hepatitis B virus serological profile and the diagnostic utility of HBcrAg across Osun and Plateau State, Nigeria [0.03%]
尼日利亚奥颂州和 plateau 州乙肝病毒血清学谱系的战略分析及 HBcrAg 的诊断应用价值
Priscilla Abechi,Uwem E George,Olamide Y Aborisade et al.
Priscilla Abechi et al.
Hepatitis B virus (HBV) infection remains a major concern in Nigeria. Nationally, increasing infection rates continue to pose a significant challenge, which may be due to inadequate diagnosis. Known markers, such as Hepatitis B Surface Anti...
The association between single-nucleotide polymorphisms of FDPS Rs2297480 and MECP2 Rs2734647 genes and the susceptibility to rheumatoid arthritis in Egyptian patients [0.03%]
FDPS基因Rs2297480和MECP2基因Rs2734647多态性与埃及类风湿关节炎患者易感性的关联分析
Nesreen G Elhelbawy,Basant F Saad,Ibrahim El Tantawy El Sayed et al.
Nesreen G Elhelbawy et al.
Background: Rheumatoid arthritis (RA) has a complex etiology that involves environmental and genetic variables. The identification of new genetic connections contributes to accelerating the development of customized medic...
Pivotal role of interleukin 27 serum level and missense variant (rs181206) in multiple sclerosis [0.03%]
白细胞介素27血清水平及其错义突变体(rs181512)在多发性硬化中的重要作用
Amany E Elashkar,Marwa M Khalil,Mona S Elkholy et al.
Amany E Elashkar et al.
The incidence of multiple sclerosis (MS) has increased in recent years. Its pathogenesis involves the interaction between various elements, with interleukin 27 (IL-27) playing a key role in autoimmunity. The presence of the IL-27 receptor o...
pcDNA3.1- rpfB or pcDNA3.1- rpfD recombinant DNA prevents Mycobacterium tuberculosis infection in BALB/c mice [0.03%]
重组DNA(pcDNA3.1-rpfB或pcDNA3.1-rpfD)可预防BALB/c小鼠感染结核杆菌
Andriansjah Rukmana,Jongga Adiyaksa,Fithriyah Sjatha et al.
Andriansjah Rukmana et al.
Tuberculosis (TB) is caused by an infection with Mycobacterium tuberculosis. The Bacille Calmette-Guérin (BCG) vaccine is used to treat TB. However, its efficacy varies in different countries. A new TB vaccine is urgently required to inhib...
Forensic significance of ELISA technique for hormone assessment: a comprehensive review [0.03%]
免疫测定技术在法医学中的意义及作用综述
Radhika Agarwal,Tejasvi Pandey,Deeksha Verma et al.
Radhika Agarwal et al.
Enzyme-linked immunosorbent assay (ELISA) is a rapid, sensitive, and economical tool for detecting hormones in diverse biological matrices, making it valuable in forensic endocrinology. This review summarizes ELISA's principles, application...
Development and validation of a cell-based methodology to evaluate filgrastim relative affinity to granulocyte colony-stimulating factor receptor [0.03%]
(filgrastim相对粒细胞集落刺激因子受体亲和力的)基于细胞的方法的研发与验证
Víctor R Campos-García,Lilia Tierrablanca-Sánchez,Nancy D Ramírez-Ibáñez et al.
Víctor R Campos-García et al.
Filgrastim, a therapeutic protein for the treatment of neutropenia, exerts its biological activity by interacting with the granulocyte colony-stimulating factor receptor. However, the affinity of filgrastim to its receptor is usually overlo...
Exploring the therapeutic potential of syringaldehyde in imiquimod-induced psoriasis model in mice via NF-κB pathway inhibition [0.03%]
通过NF-κB途径抑制在咪喹莫德诱导的小鼠银屑病模型中探索香草醛的治疗潜力
Meeral Gosia,Angel Godad,Akshata Pahelkar et al.
Meeral Gosia et al.
Psoriasis is characterized by increased levels of pro-inflammatory cytokines, including TNF-α, IL-1β, IL-17A, and NF-κB, as well as keratinocyte hyperproliferation and epidermal thickening. Its pathophysiology is significantly influenced...
CDX2 immunohistochemical marker for Barett's esophagus: useful or useless? CDX2 in Barett's esophagus [0.03%]
CDX2免疫组化标记在巴雷特食管中是否有用？
Sarra Ben Rejeb,Yasmine Chaabane,Dhouha Bacha et al.
Sarra Ben Rejeb et al.
The diagnosis of Barrett's esophagus (BE) is challenging in the absence of goblet cells (GC). Immunohistochemistry (IHC) may be useful to highlight intestinal differentiation in samples lacking GC. In this study, we aimed to describe the IH...
Treatment of cystic fibrosis pulmonary exacerbation and serum levels of neuropeptides [0.03%]
囊性纤维化肺部急性加重的治疗及其血清神经肽水平的关系研究
Maha S Al-Keilani,Roba Bdeir,Basima A Almomani et al.
Maha S Al-Keilani et al.
The identification of biomarkers for pulmonary exacerbations in cystic fibrosis (CF) is inevitable. We aimed to evaluate the serum levels of substance p (SP), neuropeptide Y (NPY), and Pituitary Adenylate Cyclase Activating Polypeptide (PAC...