Exploring the therapeutic potential of syringaldehyde in imiquimod-induced psoriasis model in mice via NF-κB pathway inhibition [0.03%]
通过NF-κB途径抑制在咪喹莫德诱导的小鼠银屑病模型中探索香草醛的治疗潜力
Meeral Gosia,Angel Godad,Akshata Pahelkar et al.
Meeral Gosia et al.
Psoriasis is characterized by increased levels of pro-inflammatory cytokines, including TNF-α, IL-1β, IL-17A, and NF-κB, as well as keratinocyte hyperproliferation and epidermal thickening. Its pathophysiology is significantly influenced...
CDX2 immunohistochemical marker for Barett's esophagus: useful or useless? CDX2 in Barett's esophagus [0.03%]
CDX2免疫组化标记在巴雷特食管中是否有用？
Sarra Ben Rejeb,Yasmine Chaabane,Dhouha Bacha et al.
Sarra Ben Rejeb et al.
The diagnosis of Barrett's esophagus (BE) is challenging in the absence of goblet cells (GC). Immunohistochemistry (IHC) may be useful to highlight intestinal differentiation in samples lacking GC. In this study, we aimed to describe the IH...
Treatment of cystic fibrosis pulmonary exacerbation and serum levels of neuropeptides [0.03%]
囊性纤维化肺部急性加重的治疗及其血清神经肽水平的关系研究
Maha S Al-Keilani,Roba Bdeir,Basima A Almomani et al.
Maha S Al-Keilani et al.
The identification of biomarkers for pulmonary exacerbations in cystic fibrosis (CF) is inevitable. We aimed to evaluate the serum levels of substance p (SP), neuropeptide Y (NPY), and Pituitary Adenylate Cyclase Activating Polypeptide (PAC...
Ki67 immunoexpression in different histological grades of Oral squamous cell carcinoma: a retrospective study [0.03%]
口腔鳞状细胞癌不同组织学分级中的Ki67免疫表达：一项回顾性研究
Rashmi Wankhade,Pratibha Dawande,Nandkishor Bankar
Rashmi Wankhade
Oral squamous cell carcinoma (OSCC) accounts for over 90% of all oral malignancies and has a 50-60% five-year survival rate, despite advances in treatment. Ki67, a nuclear protein involved in cellular proliferation, has been studied as a pr...
Oxidative-antioxidative balance and stromal cell-derived factor-4 in generalized anxiety disorder: implications for pathophysiology and biomarker potential [0.03%]
氧化-抗氧化平衡和基质细胞衍生因子-4在广泛性焦虑障碍中的意义：发病机制及生物标志物潜能的启示
Sidika Baziki Çetİn,Ülker Atilan Fedai,Öznur Akil et al.
Sidika Baziki Çetİn et al.
This study explores the relationship between oxidative - antioxidative balance and stromal cell-derived factor-4 (SDF-4) levels in individuals with Generalized Anxiety Disorder (GAD), aiming to clarify their roles in the disorder's pathophy...
Comparative immunodiagnostic performance of AgB1-derived synthetic peptides in human cystic echinococcosis [0.03%]
人源棘球蚴病的AgB1衍生合成肽的免疫诊断性能比较
Javier Magnone,Maite Folle,Sebastián Miles et al.
Javier Magnone et al.
Immunoassays are complementary diagnostic tools in human cystic echinococcosis (CE) despite sensitivity/specificity limitations, and synthetic peptides have been suggested to potentially overcome disadvantages reported for traditional antig...
Inflammatory and miRNA-based signatures in Hashimoto's thyroiditis and non-immune hypothyroidism [0.03%]
桥本甲状腺炎和非免疫性甲状腺功能减退症的炎症及微小核糖核酸特征标志物分析
Ali Abed Lafta,Farhan Abood Risan,Suhad Hassan Aubaid
Ali Abed Lafta
Hypothyroidism encompasses both autoimmune forms, notably Hashimoto's thyroiditis (HT), and nonimmune hypothyroidism (NIHT), each driven by distinct molecular mechanisms. Despite overlapping clinical features, their specific molecular diffe...
Correlation of antimicrobial peptide Human β Defensin-2 with clue cell appearance and the type of culture isolate in women with spontaneous and recurrent pregnancy losses [0.03%]
人类β防御素-2与抗菌肽在自发性和复发性流产女性中与线索细胞外观和培养分离物类型的关联性研究
Hind M Al-Khazrajy,Siham Sh Al-Salihi
Hind M Al-Khazrajy
Human β Defensin-2 (HBD2) is an Antimicrobial peptide (AMP) that serves a dual function in host defense and fertility. On the other hand, a plethora of microbial infectious agents have been associated with an increased risk of spontaneous ...
Development of analytical methods for detection of anti-drug antibodies neutralizing IL-15 and TGF-β RII activity [0.03%]
用于检测抗药物中和IL-15和TGF-β RII活性的抗体的分析方法的发展
Gilles M Leclerc,Jack O Egan,Lijing You et al.
Gilles M Leclerc et al.
To comply with regulatory guidelines and ensure that biopharmaceutical agents meet safety and efficacy, we developed an analytical method to detect anti-drug antibodies (ADAs) generated in response to HCW9218, a fusion molecule containing t...
An indirect competitive ELISA assay using fragment antigen-binding (Fab) antibody for the quantitative detection of delta-9-tetrahydrocannabinol from Cannabis sativa L [0.03%]
一种间接竞争性酶联免疫吸附测定法，利用抗原结合片段（Fab）抗体对大麻植物中的Δ-9-四氢大麻酚进行定量检测
Worapol Sae-Foo,Jakkapat Paluka,Pewpan Maleewong Intapan et al.
Worapol Sae-Foo et al.
Delta-9-tetrahydrocannabinol (THC) is one of the cannabinoid metabolites present in Cannabis sativa. Currently, cannabis is an ingredient in foods, cosmetics, and medicinal products. Many countries control cannabis and THC for illegal or un...