Third trimester stillbirth during the first wave of the SARS-CoV-2 pandemic: Similar rates with increase in placental vasculopathic pathology [0.03%]
SARS-CoV-2疫情第一波时期的晚期妊娠死胎及其胎盘血管病变病理的增加
Megan E Bunnell,Kathleen J Koenigs,Drucilla J Roberts et al.
Megan E Bunnell et al.
Whether early SARS-CoV-2 definitively increases the risk of stillbirth is unknown, though studies have suggested possible trends of stillbirth increase during the pandemic. This study of third trimester stillbirth does not identify an incre...
The (pro)renin receptor ((P)RR) and soluble (pro)renin receptor (s(P)RR) in pregnancy [0.03%]
妊娠期的促肾素致活酶/促肾素受体及可溶性促肾素致活酶/促肾素受体
Saije K Morosin,Alyssa J Lochrin,Sarah J Delforce et al.
Saije K Morosin et al.
The (pro)renin receptor ((P)RR) is a multi-functional protein that can be proteolytically cleaved and released in a soluble form (s(P)RR). Recently, the (P)RR and s(P)RR have become of interest in pregnancy and its associated pathologies. T...
Endocytosis in the placenta: An undervalued mediator of placental transfer [0.03%]
胎盘内的内吞作用：一种被低估的胎盘转移调解机制
Laura D F Cooke,David A Tumbarello,Nicholas C Harvey et al.
Laura D F Cooke et al.
Endocytosis is an essential mechanism for cellular uptake in many human tissues. A range of endocytic mechanisms occur including clathrin-dependent and -independent mechanisms. However, the role of endocytosis in the placenta and the spatia...
microRNA-210/ Long non-coding RNA MEG3 axis inhibits trophoblast cell migration and invasion by suppressing EMT process [0.03%]
微RNA-210/长链非编码RNA MEG3轴通过抑制上皮间质转化过程来抑制滋养细胞迁移和侵袭
Rongli Wang,Li Zou,Xinyuan Yang
Rongli Wang
Introduction: Pre-eclampsia is characterized by insufficient spiral artery remodeling, and trophoblast dysfunction plays an important role in this process. Noncoding RNAs (microRNAs (miRNAs) and long noncoding RNAs (LncRN...
Circulating angiogenic profiles and histo-morphological placental characteristics of uncomplicated post-date pregnancies [0.03%]
过期妊娠正常组血清中血管生成谱型及胎盘组织形态学特征的研究
Birgitte Mitlid-Mork,Gitta Turowski,Sophie Bowe et al.
Birgitte Mitlid-Mork et al.
Introduction: The objectives of this study were to describe the histo-morphology of post-date placentas in clinically uncomplicated pregnancies without adverse delivery outcomes and the association with maternal circulati...
Paradigms for investigating invasive trophoblast cell development and contributions to uterine spiral artery remodeling [0.03%]
用于探究入侵性合胞细胞发育和对子宫螺旋动脉重塑作用的模型体系
Kaela M Varberg,Michael J Soares
Kaela M Varberg
Uterine spiral arteries are extensively remodeled during placentation to ensure sufficient delivery of maternal blood to the developing fetus. Uterine spiral arterial remodeling is complex, as cells originating from both mother and developi...
Late/post-term decidual basalis-derived mesenchymal stem/stromal cells show evidence of advanced ageing and downregulation of microRNA-516b-5p [0.03%]
过期妊娠蜕膜基质干细胞出现衰老迹象并下调微小核糖核酸-516b-5p的表达
Ramin Khanabdali,Shixuan Zheng,Phillip E Melton et al.
Ramin Khanabdali et al.
Introduction: The placenta is a short-lived organ, yet it shows signs of progressive ageing in the third trimester. Studies of ageing chorionic placental tissue have recently flourished, providing evidence of advanced age...
Intermembrane distances at the feto-maternal interface in epitheliochorial placentation [0.03%]
上皮绒毛膜胎盘屏障处的胎盘母体界面间距离
Karl Klisch,Elisabeth M Schraner
Karl Klisch
Introduction: In an epitheliochorial placenta, the apical membranes of trophoblast cells and of uterine epithelial cells are in contact to each other (feto-maternal contact). In addition, there are also folds in which the...
Is endothelial function impaired among women with placenta-mediated fetal growth restriction? Evidence from a prospective cohort study using peripheral artery tonometry [0.03%]
胎盘介导的胎儿生长受限妇女的内皮功能障碍吗？外周动脉 toneometry 的前瞻性队列研究证据
Michal Kirshenbaum,Lior Topaz,Micha Baum et al.
Michal Kirshenbaum et al.
Introduction: Women with pregnancies complicated by IUGR are at increased risk for future cardiovascular disease. Nevertheless, it is unknown whether endothelial function of women with pregnancies complicated by IUGR is a...
Observational Study
Placenta. 2021 Jun:109:32-36. DOI:10.1016/j.placenta.2021.04.013 2021
A crossroad between placental and tumor biology: What have we learnt? [0.03%]
胎盘和肿瘤生物学的交叉领域：我们学到了什么？
Peeyush K Lala,Pinki Nandi,Ali Hadi et al.
Peeyush K Lala et al.
Placenta in certain species including the human has evolved as a highly invasive tumor-like organ invading the uterus aned its vasculature to derive oxygen and nutrients for the fetus and exchange waste products. While several excellent rev...