A placental specific miRNA miR-517a-3p exerts anti-human cytomegalovirus activity [0.03%]
胎盘特异性miRNA miR-517a-3p对人巨细胞病毒具有抑制活性
Stuart T Hamilton,Friedrich Hahn,Eric Sonntag et al.
Stuart T Hamilton et al.
Human cytomegalovirus congenital infection is the leading non-genetic cause of fetal malformation in developed countries. There are currently no safe antivirals for use during pregnancy. Placental trophoblast cells specifically secrete exos...
Molar pregnancy in the last 50 years: A bibliometric analysis of global research output [0.03%]
过去50年中外文文献中葡萄胎研究的 bibliometric 分析
Ourlad Alzeus G Tantengco,Federico Cristobal C De Jesus nd,Eloina Faye S Gampoy et al.
Ourlad Alzeus G Tantengco et al.
Molar pregnancy is a gestational trophoblastic disease characterized by an abnormal growth of placental tissues because of a nonviable pregnancy. The understanding of the pathophysiology and management of molar pregnancy has significantly i...
The metabolic landscape of decidua in recurrent pregnancy loss using a global metabolomics approach [0.03%]
复发性妊娠丢失患者子宫内膜代谢轮廓的全局代谢组学研究
Li-Ling Wang,Hong Liu,Si-Jia Zhao et al.
Li-Ling Wang et al.
Introduction: Maternal metabolism undergoes dynamic changes during pregnancy. A deviation from this physiological metabolic status might be involved in the pathogenesis of pregnancy complications, such as recurrent pregna...
Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats [0.03%]
病毒感染引起的母体免疫反应可改变大鼠胎盘AMPK和mTORC1信号转导路径
Eliza R McColl,Micheline Piquette-Miller
Eliza R McColl
Introduction: Maternal immune activation (MIA) is associated with neurodevelopmental disorders in offspring. We previously demonstrated that poly(I:C)-mediated MIA alters placental and fetal brain amino acid transporter e...
Short tandem repeat analysis to identify the causative pregnancy of high-risk gestational trophoblastic neoplasia: Molar versus nonmolar pregnancy and its relation to the outcome [0.03%]
短串联重复分析鉴别高危妊娠滋养细胞肿瘤的致病性妊娠：葡萄胎与非葡萄胎及其结局的关系
Kimihiro Nishino,Eiko Yamamoto,Yukari Oda et al.
Kimihiro Nishino et al.
Introduction: Gestational trophoblastic neoplasia (GTN) include a group of malignant neoplasms that originate from the trophoblasts of placental tissue in molar or nonmolar pregnancy. Currently, it is unclear whether the ...
Case Reports
Placenta. 2021 Sep 1:112:28-35. DOI:10.1016/j.placenta.2021.06.015 2021
Passively inhaled tobacco smoke - pregnancy and neonatal outcomes in correlation with placental histopathology [0.03%]
被动吸入烟草烟雾与胎盘病理变化及妊娠和新生儿结局的相关性研究
Michal Levy,Michal Kovo,Emilie Ben-Ezry et al.
Michal Levy et al.
Introduction: We aimed to investigate the effect of maternal passive smoking (MPS) during pregnancy-on placental pathology and pregnancy outcomes. Methods...
HMGB1 regulates lipopolysaccharide-induced cellular dysfunction in HTR8/SVneo cells: Implications for the role of HMGB1 in unexplained spontaneous miscarriage [0.03%]
高迁移率族蛋白B1调节脂多糖诱导的HTR8/svneo细胞功能障碍：在不明原因的自然流产中高迁移率族蛋白B1的作用意义
Feng Zhou,Yan Wang,Yan Tan et al.
Feng Zhou et al.
Introduction: Approximately half of miscarriages are of an unknown aetiology and are likely characterized by aberrant inflammation at the uteroplacental interface. High mobility group box 1 (HMGB1) is a ubiquitous nuclear...
Human placental gene sets improve analysis of placental pathologies and link trophoblast and cancer invasion genes [0.03%]
人类胎盘基因数据集可改进胎盘病理分析并连接滋养层和癌症侵袭基因
Kendra Naismith,Brian Cox
Kendra Naismith
Introduction: Interpretation of gene expression uses set enrichment or overrepresentation methods that depend on sets of annotated genes, such as the popular Gene Ontology. The placenta is understudied relative to other m...
AOPPs induce HTR-8/SVneo cell apoptosis by downregulating the Nrf-2/ARE/HO-1 anti-oxidative pathway: Potential implications for preeclampsia [0.03%]
AOPPs通过下调Nrf-2/ARE/HO-1抗氧化途径诱导HTR-8/SVneo细胞凋亡：在子痫前期中的潜在作用
Shuying Chen,Qian Yin,Haoyue Hu et al.
Shuying Chen et al.
Introduction: Advanced oxidation protein products (AOPPs), which are novel markers of oxidant-mediated protein damage, are prevalent in numerous diseases. We previously demonstrated that AOPPs act as a new class of pathog...
Characterization of vitelline vessel remnant circulation in the umbilical cord [0.03%]
胎盘脐带血管残留物的特征化研究
John Kemuel De Guzman,Weiming Yu,Christopher Horn et al.
John Kemuel De Guzman et al.
The vitelline circulation normally regresses by about 10 weeks gestation. Vitelline vessel remnants (VVRs) are found in approximately 4-11% of umbilical cords. While these remnants retain an active fetal circulation, this has never been stu...