Investigating the abnormalities and potential therapeutic targets in umbilical cord mesenchymal stem cells from preeclampsia [0.03%]
子痫前期脐带间充质干细胞异常及潜在治疗靶点的研究
Fei He,We Cai,Shaoru Cai et al.
Fei He et al.
Background: Damaged cells are influenced by their microenvironment, which may lead to abnormalities. In preeclampsia (PE), several abnormal changes can occur that affect the umbilical cord and, consequently, umbilical cor...
NOTCH, WNT, and TGFβ: Key pathways in extravillous trophoblast formation and differentiation [0.03%]
notch，wnt和tgfb：参与细胞外滋养层形成与分化的重要通路
Gudrun Meinhardt,Sandra Haider
Gudrun Meinhardt
During gestation, the human placenta ensures nutrition, gas exchange, and protection against pathogens for the growing fetus. As key component in placentation, extravillous trophoblasts (EVTs) arise from trophoblast (TB) progenitors through...
Massive subchorionic thrombohematoma (Breus' mole): An exceedingly rare placental disorder-Case series and systematic review [0.03%]
巨大的亚胎盘血肿（布劳斯胎）：一种极为罕见的胎盘疾病-病例系列和系统性回顾
Eva Manuela Pena-Burgos,Inmaculada Duyos-Mateo,Laura Hato-Salmón et al.
Eva Manuela Pena-Burgos et al.
Introduction: Breus' mole, or massive subchorionic thrombohematoma (MST), is an exceedingly rare placental condition associated with adverse pregnancy outcomes. We aim to describe the clinical, ultrasonographic, and histo...
Comprehensive assessment of uterine contractility using a large database of dynamic T2∗ studies [0.03%]
利用T2*动态研究大型数据库全面评估子宫收缩功能
Jordina Aviles Verdera,Kelly Payette,Megan Hall et al.
Jordina Aviles Verdera et al.
Introduction: Uterine contractile activity, essential for vaginal birth, begins early in gestation, but quantitative assessment remains limited. T2∗ relaxometry detects placental oxygenation changes during contractions, ...
Gardnerella vaginalis impairs extravillous trophoblast invasion via extracellular matrix-mediated MMP2 downregulation [0.03%]
加德纳菌通过细胞外基质介导的MMP2下调抑制蜕膜血管内皮细胞侵袭能力
Yoshinori Takeda,Kazuhide Takada,Takahiro Namiki et al.
Yoshinori Takeda et al.
Introduction: Proper placental development is crucial during pregnancy, and extravillous trophoblasts (EVTs) play a key role in this process. Disturbances in EVT invasion are associated with complications, such as inferti...
Preeclampsia: The silent catalyst for autism spectrum disorder in offspring [0.03%]
子痫前期：儿童自闭症的隐性催化剂
Zilin Mei,Sha Yang,Linjun Li et al.
Zilin Mei et al.
Preeclampsia, a pregnancy-specific disorder characterized by hypertension and proteinuria, has been hypothesized to be associated with the development of autism spectrum disorder (ASD) in offspring. This review synthesizes epidemiological e...
Yuan Zhang,Ruiping Lu,Yulan Ma et al.
Yuan Zhang et al.
Objective: Hyperhomocysteinemia (HHcy), characterized by elevated homocysteine levels, is associated with adverse pregnancy outcomes, though its mechanistic link to placental dysfunction remains unclear. This study aimed ...
Gross patterns of umbilical cord coiling in pregnancies with and without gestational diabetes mellitus [0.03%]
糖尿病妊娠和非糖尿病妊娠脐带缠绕模式的形态学研究
Napaporn Puripat,Chutima Chavanisakun,Petcharat Jenkumwong et al.
Napaporn Puripat et al.
Introduction: Gestational diabetes mellitus (GDM) may influence the umbilical cord coiling index, but its effect on gross coiling patterns remains unclear. This study compared umbilical cord coiling patterns in pregnancie...
Functional androgen signaling pathway potentiates maternal-fetal interactions------ implantation, placentation and early pregnancy maintenance [0.03%]
功能性雄激素信号通路促进母胎相互作用——着床、胎盘形成及早孕维持
Yang Zhao,Jiawen Xu,Caixia Liu et al.
Yang Zhao et al.
A growing body of evidence demonstrates that androgens play crucial roles in female reproductive physiology. Androgen receptor (AR) expression appears at all levels of the hypothalamic-pituitary-gonadal axis and other female reproductive or...
The effects of natural versus programmed frozen embryo transfer cycles on placental histopathology [0.03%]
自然受孕与刺激周期对胎盘病理生理的影响
Alexandre Machado-Gédéon,Hadas Ganer Herman,Alexander Volodarsky-Perel et al.
Alexandre Machado-Gédéon et al.
Objective: Determine if type of endometrial preparation protocol for frozen embryo transfer (FET), whether natural cycle (NC) or programmed with hormone replacement therapy (HRT), affects placental histopathology. ...