Integrated placental and neonatal urinary detection of Ureaplasma urealyticum: A translational approach to predicting adverse neonatal outcomes [0.03%]
尿解脲支原体的联合胎盘和新生儿尿检：预测不良新生儿结局的转化方法
Yanxue Yin,Huayan Ren,Juan Li et al.
Yanxue Yin et al.
Introduction: Ureaplasma urealyticum (U. urealyticum) commonly colonizes the maternal genital tract and contributes to intrauterine infection. However, the clinical relevance of U. urealyticum detection in neonatal urine,...
Jiancai Yin,Ziyan Zhao,Weilong Lin et al.
Jiancai Yin et al.
Objective: Preeclampsia, a placenta disorder characterized by angiogenic imbalance, remains etiologically undefined. This research investigated the role of angiopoietin-2 (ANGPT2) dysregulation in preeclampsia-associated ...
Exosomal miR-152-5p promotes trophoblast apoptosis by inhibiting the PI3K/AKT/FOXO3a signaling pathway via targeting VAMP3 in gestational diabetes mellitus [0.03%]
外泌体miR-152-5p通过靶向VAMP3抑制PI3K/AKT/FOXO3a信号通路促进妊娠糖尿病胎盘绒毛膜滋养细胞凋亡
Yuan Zhang,Jiabin Ren,Tiantian Yu et al.
Yuan Zhang et al.
Introduction: Trophoblast apoptosis is a major cause of adverse pregnancy outcomes in patients with gestational diabetes mellitus (GDM). The aim of this study was to investigate the mechanism of action of exosomal microRN...
Chronic mild maternal stress modulates the immune response at the maternal-fetal interface and affects the growth and mortality of the offspring [0.03%]
慢性轻度母体压力调节母胎界面免疫反应并影响子代的生长和存活率
F L De la Cruz Borthiry,J S Beltrame,V A Cañumil et al.
F L De la Cruz Borthiry et al.
Maternal lifestyle influences the health of both the mother and fetus. Acute stress is detrimental to health and increases the risk of obstetric complications. However, the consequences of chronic mild stress are less understood. We investi...
Possible involvement of a ZC3H4 gene splicing defect in the etiology of pre-eclampsia [0.03%]
ZC3H4基因剪接异常可能与子痫前期发病机制有关
Hikari Yoshizawa,Hidehito Inagaki,Rei Yoshimoto et al.
Hikari Yoshizawa et al.
Introduction: Alternative RNA splicing adds diverse variations to gene function, and its abnormalities are occasionally associated with the etiology of disease. We examined this possibility in pre-eclampsia. ...
Maternal organophosphate pesticide exposure in relation to birthweight: Modification by placenta transporter genotype [0.03%]
母亲有机磷农药暴露与新生儿体重的关系：关于胎盘转运蛋白基因型的调节作用
Duong Q Nguyen,Sara Hyman,Eleanor Medley et al.
Duong Q Nguyen et al.
Exposure to organophosphate pesticides (OPPs) has been linked to adverse birth outcomes, including low birthweight. Maternal biomarkers are commonly used as proxies for fetal exposure, but fetal exposure also depends on placental transport ...
Human placental impact from exposure to non-smoked tobacco and nicotine products: A scoping review [0.03%]
烟草和尼古丁制品暴露对人胎盘影响的范畴综述
Mascha Bosnjak,Elizabeth A Burmeister,Angela Ratsch
Mascha Bosnjak
Globally, non-smoked tobacco and nicotine containing products (NST&N) including nicotine replacement therapy are now widely used during pregnancy, yet evidence on human placental development and function which isolates the effects of nicoti...
Exogenous hydrogen sulfide ameliorates hypoxia-induced trophoblast dysfunction by modulating cellular energy metabolism: A role in preeclampsia [0.03%]
外源性氢硫化物通过调节细胞能量代谢改善胎盘滋养细胞低氧损伤的机制研究在子痫前期发病中的作用探讨
Jiahui Chen,Jing Huai,Ruilin Guo et al.
Jiahui Chen et al.
Introduction: Preeclampsia (PE) is characterized by abnormal trophoblast energy metabolism. Hydrogen sulfide (H2S), a key signaling molecule, modulates cellular energy, but its role in PE is unclear. This study investigat...
Placental mosaicism for structural chromosomal variants: follow-up of 251 Danish cases (1983-2021) [0.03%]
胎盘嵌合体的结构染色体重排变异的随访研究（1983-2021年，丹麦）
Simon Horsholt Thomsen,Ida Charlotte Bay Lund,Iben Bache et al.
Simon Horsholt Thomsen et al.
Introduction: Mosaicism, the presence of two or more chromosomally different cell lines in the same tissue, is detected in 2-4 % of chorionic villus samples (CVS). Its detection presents clinical challenges, as follow-up ...
Viscoelasticity quantification by ultrasound for placental assessment in healthy versus gestational diabetes mellitus pregnancies [0.03%]
超声波量化胎盘粘弹性能以评估健康与妊娠糖尿病孕妇的区别
Jing Zhang,Jiahao Han,Lu Chen et al.
Jing Zhang et al.
Introduction: Viscosity is a novel parameter, recently introduced in the use of elastographic techniques. Ultrasound viscoelastic imaging quantifies tissue stiffness and viscosity. This study investigated its application ...