Adipokine visfatin as a response of an efficient placenta to key pregnancy risk factors [0.03%]
妊娠危险因素的有效胎盘反应标志物——脂肪细胞因子visfatin
Aleksandra Stangret,Anna Wnuk,Zbigniew Lewandowski et al.
Aleksandra Stangret et al.
Introduction: Visfatin is a multifunctional adipokine, primarily produced by visceral fat but also expressed in the placenta, where it may contribute to pregnancy regulation. Obesity, advanced maternal age are associated ...
Adenosine promotes trophoblast proliferation without inducing differentiation or apoptosis [0.03%]
腺苷促进滋养细胞增殖而不诱导分化或凋亡
Mohammed N H Ali,Mariia Adler,Magdalena Novotna et al.
Mohammed N H Ali et al.
Objective: Adenosine and other nucleosides are essential regulators of cellular processes, but their specific roles in trophoblast growth and regulation remain incompletely defined. This study investigated the effects of ...
Placental dysfunction and neonatal mortality induced by Salmonella Abortusequi in a murine model of pregestational infection [0.03%]
宋内志贺菌诱发的妊娠前感染小鼠模型胎盘功能障碍及新生儿死亡率研究
Diana M Betancourt,Mariángeles Noto Llana,Ailín N Garófalo et al.
Diana M Betancourt et al.
Introduction: Salmonella Abortusequi is a host-restricted equine pathogen and a major cause of abortion in mares, threatening reproductive health and industry sustainability. This study was aimed to identify factors that ...
Determination of residue aspirin and its bioactive metabolites in human placenta: Application to high-risk to preeclampsia women received prophylactic low-dose aspirin [0.03%]
人胎盘中残留的阿司匹林及其生物活性代谢物的测定：在高风险子痫前期患者预防性低剂量使用阿司匹林中的应用
Kenean Getaneh Tlaye,So Pui Kin,Gashaw Garedew Woldeamanuel et al.
Kenean Getaneh Tlaye et al.
Introduction: The human placenta plays central role in preeclampsia (PE) pathogenesis and may modulate the effectiveness of prophylactic low-dose aspirin (LDA). In this study, we optimized and validated LC-MS/MS method to...
Histopathologic placental findings in severe acute respiratory syndrome coronavirus 2 exposed gravida compared to unexposed controls: a single center retrospective cohort study [0.03%]
新冠病毒暴露与未暴露的妊娠胎盘病理改变：一项单中心回顾性队列研究中的发现差异
Burk Schaible,Jefferey Shenberger,Ingrid Tablazon et al.
Burk Schaible et al.
Background: Little is known about the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the placenta. Existing studies have study design limitations but suggest a relationship between SARS-CoV-2 an...
Association between MRI-derived early second trimester placental physiology and birth weight percentiles in pregnancies without ischemic placenta disease (IPD) [0.03%]
无缺血性胎盘病的妊娠在早期第二孕期取MRI获得的胎盘生理学特征与新生儿体重百分位数的关系
Raymi O Ramirez,Jennifer J Kim,Precious Ann Fortes et al.
Raymi O Ramirez et al.
Introduction: This study investigated whether placental structure and function, measured using multiparametric MRI (mpMRI) in early second trimester, are associated with birth weight percentiles. We focused on pregnancies...
Metformin mitigates placental dysfunction by modulating gene expressions in a high-fat diet-induced rat model [0.03%]
二甲双胍通过调节基因表达改善高脂饮食诱导的大鼠妊娠期胎盘功能异常
Yu-Ju Lin,Yin-Hua Cheng,Ni-Chin Tsai et al.
Yu-Ju Lin et al.
Background: Maternal obesity impairs placental development and function, contributing to adverse fetal outcomes through disrupted gene regulation and metabolic homeostasis. Metformin, an insulin-sensitizing agent, may mit...
Discovery of placental microRNAs associated with maternal insulin sensitivity during pregnancy [0.03%]
与妊娠期母体胰岛素敏感性相关的胎盘microRNA的发现
Sana Majid,Imad Soukar,Frédérique White et al.
Sana Majid et al.
Context: During pregnancy, maternal insulin sensitivity decreases, supporting transfer of nutrients to the fetus; when excessive, this can lead to gestational diabetes mellitus. The physiological decline in insulin sensit...
The relationship between preeclampsia subtypes and birth weight to placental weight ratio: Insights from a study of 17,709 pregnant Japanese women [0.03%]
子痫前期亚型与出生体重至胎盘重量比率的关系——基于日本17709名孕妇的研究启示
Hisashi Ohseto,Mami Ishikuro,Genki Shinoda et al.
Hisashi Ohseto et al.
The placenta plays a crucial role in preeclampsia (PE) pathogenesis, with early onset (EOPE) and late onset (LOPE) presenting with unique manifestations. In this prospective study of 17,709 pregnant Japanese women, the relationship between ...
The monster villus: A rare, but characteristic, feature of human placentas in diabetes mellitus [0.03%]
糖尿病患者胎盘的罕见但特征性表现-怪兽绒毛增多症
Berthold Huppertz,Marina Ivanisevic,Gernot Desoye
Berthold Huppertz
Context: Villous tree development of the human placenta is mostly driven by spatial organization of vessels. Diabetes in pregnancy is associated with structural alterations of the placenta, including hypervascularization ...