Growth differentiation factor-8 promotes human extravillous trophoblast cell invasion by increasing ANGPTL4 expression [0.03%]
生长分化因子8通过增加ANGPTL4表达促进人绒毛外滋养细胞侵袭能力
Shenghui Zhou,Beibei Bi,Ze Wu et al.
Shenghui Zhou et al.
Introduction: Proper regulation of extravillous trophoblast (EVT) cell invasion is critical for normal placental development and function. Angiopoietin-like 4 (ANGPTL4), a multifunctional protein, has previously been impl...
DEHP exposure alters carcinoembryonic antigen family member transcript levels and modulates responses to activin A in the murine placenta [0.03%]
DEHP暴露可改变小鼠胎盘癌胚抗原家族成员转录水平并调节其对活化素A的反应
Lacey Klompmaker,Sarah C Moody,Junlan Iris Ma et al.
Lacey Klompmaker et al.
Introduction: Activin A affects placental decidualisation and trophoblast growth and invasion. Levels increase during pregnancy, peaking at parturition, while premature elevation is a hallmark of several pregnancy disorde...
Liza Konnikova
Liza Konnikova
Preterm birth (PTB), defined as delivery before 37 weeks of gestation, is a leading cause of infant mortality worldwide, with nearly 10 % of births in the U.S. being preterm. PTB leads to various complications, including respiratory, neurol...
Inflammation-induced TET3/mir-3942 axis impedes the proliferation and invasion ability of trophoblast cells through destabilization of SERPINE1 in preeclampsia [0.03%]
炎症诱导的TET3/mir-3942轴通过降低SERPINE1的稳定性抑制子痫前期滋养细胞的增殖和侵袭能力
Xiaokang Deng,Qing Zuo,Yi Liu et al.
Xiaokang Deng et al.
Introduction: Abnormal expression of TET3 has been established to be associated with aberrant function of trophoblasts and lead to the progression of Preeclampsia (PE). Yet, the underlying mechanism of PE mediated by TET3...
Endoplasmic reticulum stress induces trophoblast pyroptosis via regulating CYLD during labor initiation [0.03%]
胎盘屏障功能形成及维持的免疫机制研究进展
Xiaolei Zhang,Meitao Yang,Dan Lv et al.
Xiaolei Zhang et al.
Introduction: Preterm birth (PTB) presents significant risks to neonatal health, highlighting a deeper understanding of the mechanisms underlying labor initiation. Maternal-fetal interface inflammation and heightened endo...
Correlation between first trimester placental growth factor levels and skin microvascular reactivity assessed by laser speckle contrast imaging - a cross-sectional study [0.03%]
妊娠早期胎盘生长因子与皮肤微血管反应性激光散斑对比成像横断面研究关系分析
Mor Huri,Isabella Abati,Chiara Bartolini et al.
Mor Huri et al.
Objectives: To investigate the association between first-trimester placental growth factor (PlGF) levels and maternal skin microvascular reactivity, as assessed by laser speckle contrast imaging (LSCI) combined with post-...
Presepsin in the amniotic fluid is a useful clinical inflammatory biomarker for the prenatal predictive diagnosis of histologic chorioamnionitis: a retrospective preliminary study [0.03%]
羊水中的髓过氧化物酶是产前预测诊断胎盘慢性炎症的临床炎性标志物：一项回顾性初步研究
Masamitsu Kurakazu,Daichi Urushiyama,Toyofumi Hirakawa et al.
Masamitsu Kurakazu et al.
Introduction: This study investigated whether presepsin in the amniotic fluid is a useful inflammatory biomarker for the prenatal predictive diagnose of histologic chorioamnionitis (HC). ...
Cytotoxicity and induction of proinflammatory cytokines in placental explant cells following azathioprine exposure [0.03%]
氮芥暴露后胎盘组织块细胞的细胞毒性与促炎症细胞因子的诱导作用
Franciele Rodrigues Araújo,Adriana Lopes da Silva,Leandro de Oliveira et al.
Franciele Rodrigues Araújo et al.
Immunosuppressive drugs offer hope for the survival and motherhood of women with various disorders. Although the systemic side effects of these drugs on mothers have been studied, their impact on the placenta remains poorly understood, whic...
AHR activated placental adrenomedullin: A plausible factor in smoke-induced preeclampsia protection [0.03%]
激活胎盘肾上腺髓质素：吸烟诱导子痫前期保护的可能因素
Margeaux W Marbrey,Bryan Kistner,Elizabeth S Douglas et al.
Margeaux W Marbrey et al.
Introduction: The placenta develops as trophectoderm cells invade and secrete peptides to remodel the maternal vasculature. Impaired invasion can lead to preeclampsia. Maternal smoking during pregnancy can cause miscarria...
Maternal serum heparan sulfate in preeclampsia pathophysiology: Insights from a systematic review and meta-analysis [0.03%]
子痫前期病理生理学中的母体血清硫酸肝素：系统回顾和meta分析的新见解
Alejandra María Gómez-Gutiérrez,Angela María Alvarez-Gómez,Juan Carlos Quintana-Castillo et al.
Alejandra María Gómez-Gutiérrez et al.
Preeclampsia (PE) is a hypertensive disorder that generally occurs after the first half of pregnancy, at delivery or even postpartum; it is associated with maternal organ dysfunction and significantly increases maternal, fetal, and newborn ...