Polystyrene microplastics internalization by term placental chorionic villi explants [0.03%]
胎盘终末绒毛外植体摄取聚苯乙烯微塑料及其对屏障功能的影响研究
Aldilane Lays Marques,Rodrigo Weingrill,Stephanie Ospina-Prieto et al.
Aldilane Lays Marques et al.
Introduction: Microplastics (MPs) are pervasive environmental contaminants increasingly found within human tissues, including the placenta. This study explores the potential of polystyrene (PS)-MPs to cross the placental ...
A human cytotrophoblast-villous endothelium-fetal organ multi-cell model and the impact on gene and protein expression in placenta cytotrophoblast, fetal hepatocytes and fetal kidney epithelial cells [0.03%]
人类合胞体-绒毛内皮-胎儿器官多细胞模型及其对胎盘合胞体、胎儿肝细胞和胎儿肾上皮细胞基因表达与蛋白质表达的影响
Helen N Jones,Alyssa Williams,Rebecca L Wilson
Helen N Jones
Introduction: Appropriate fetal growth requires multi-directional, coordinated communication between maternal, placental, and fetal systems. Disruptions in these signaling arms can have deleterious consequences for fetal ...
Molecular regulation and functional benefits of trophoblast syncytialization in optimizing maternal-fetal nutrient allocation [0.03%]
细胞同步带化分子调控及优化母胎营养分配的功能益处
Qianqian Li,Yuelin Zhu,Xin Yu et al.
Qianqian Li et al.
The placenta governs maternal-fetal nutrient allocation during pregnancy, primarily mediated by placental villi composed of multinucleated syncytiotrophoblasts (STBs) and mononucleated cytotrophoblasts (CTBs) in humans. STBs are formed thro...
Hystero-embryoscopy as a tool for RPL immunological research at the maternal-fetal interface [0.03%]
宫腔镜在复发性流产免疫机制研究中的应用价值探讨
Valentina Bruno,Brunella Zizolfi,Margherita Ferretti et al.
Valentina Bruno et al.
Introduction: An abnormal immune response at the fetal-maternal interface is expected in 50-60 % of unexplained Recurrent Pregnancy Loss (uRPL) cases. Detected immunophenotypes in uRPL could help in risk assessment, progn...
Plasma proteome profiling of massive perivillous fibrin deposition (MPFD) in women with recurrent Miscarriages: Pathophysiological insights and biomarker discovery [0.03%]
与复发性流产相关的胎盘血管异常患者的血浆蛋白质组特征研究及病理生理学意义和生物标志物发现
Eun Na Kim,Jiyoung Yu,Eun Hye Yoon et al.
Eun Na Kim et al.
Introduction: Massive perivillous fibrin deposition (MPFD) leads to fetal growth restriction and intrauterine demise. As MPFD is typically diagnosed following an adverse event, there is a need for serum biomarkers for ear...
Interaction of decidual macrophages and other maternal-fetal interface cells in recurrent pregnancy loss [0.03%]
复发性妊娠丢失与蜕膜巨噬细胞及其他母胎界面免疫细胞的相互作用
Wenjing Ma,Chenyu Sun,Sisi Mao et al.
Wenjing Ma et al.
Recurrent Pregnancy Loss (1) is a common pregnancy complication that can have a negative impact on both the physical and mental health of pregnant women. Despite various associations, the precise etiology of RPL remains unclear, necessitati...
Placental growth factor enhances inflammatory toll-like receptor responses in syncytiotrophoblasts [0.03%]
胎盘生长因子可增强合体滋养层的炎症 Toll 样受体反应
Laura F Newell,Shernan G Holtan,Leena Kadam et al.
Laura F Newell et al.
Introduction: Pregnancy requires that the development of immune tolerance to avoid fetal rejection is balanced with functional immune surveillance mechanisms against infectious pathogens. Trophoblast cells play a unique r...
Placental hexokinase activity is related to fetal blood flow distribution in a cross-sectional study of healthy human pregnancies at term [0.03%]
胎盘己糖激酶活性与健康人类妊娠胎儿血液循环分布相关性的一项横断面研究
Muhammad Umar Sajjad,Tore Henriksen,Guttorm Haugen et al.
Muhammad Umar Sajjad et al.
Objective: Given that placental hexokinase is a key enzyme in glucose metabolism, we hypothesized that placental hexokinase activity is related to fetal blood flow distribution in healthy pregnancies with scheduled cesare...
Genetic background influences susceptibility to exencephaly in Scavenger receptor Class B type 1-deficient mouse embryos [0.03%]
遗传背景影响清道夫受体BⅠ型敲除小鼠胚胎无脑畸形的易感性
Camila Romero-Muñoz,Patricia Romo-Toledo,Gabriela Belledonne et al.
Camila Romero-Muñoz et al.
Introduction: Neural tube defects (NTD) are congenital malformations influenced by genetic and environmental factors. Mouse embryos deficient in Scavenger Receptor Class B Type 1 (SR-B1) exhibit female-skewed cranial NTD ...
Increased protein O-GlcNAcYLATION in human placentas from hypertensive pregnancies [0.03%]
子痫前期患者胎盘中蛋白质O-GlcNAc酰化的增加
Marta de Lima Castro,Rinaldo Rodrigues Dos Passos Jr,Thiago Lopes Rocha et al.
Marta de Lima Castro et al.
Introduction: Key proteins involved in placentation are susceptible to O-linked β-N-acetylglucosamine modification (O-GlcNAcylation). Anomalies in protein O-GlcNAcylation have been associated with pathological conditions...