Cyp19a1-Cre-EGFP: A placenta-specific Cre transgenic mouse model for targeted gene recombination in trophoblast cells [0.03%]
Cyp19a1-Cre-EGFP：一种胎盘特异性Cre转基因小鼠模型，用于滋养层细胞中目标基因的重组
Shu-Min Pan,Nian-Kun Chen,Xue-Yuan Li et al.
Shu-Min Pan et al.
Objective: The placenta plays a critical role in fetal development, yet placenta-specific gene manipulation remains a challenge due to widespread gene expression across maternal and embryonic tissues. Here, we describe th...
Adaptive changes in placenta of obese pregnant women - the expression of Bcl-2 and Pim-1 [0.03%]
肥胖孕妇胎盘的适应性变化-Bcl-2和Pim-1的表达
Magdalena Danuta Opinc,Michał Golberg,Józef Kobos et al.
Magdalena Danuta Opinc et al.
Introduction: An intensification of inflammatory processes and apoptosis has been observed in pregnant women with abnormally high Body Mass Index (BMI) values. This study aimed to evaluate the expression of the anti-apopt...
Effect of hydroxychloroquine on trophoblastic invasion in relation to autophagy mediated by ET-1 and ERK [0.03%]
羟氯喹通过抑制自噬影响ET-1和ERK介导的滋养细胞侵袭能力的作用研究
Ji-Hee Sung,Suk-Joo Choi,Cheong-Rae Roh et al.
Ji-Hee Sung et al.
Introduction: Hydroxychloroquine (HCQ), which has multiple effects, including autophagy inhibition, is used to prevent obstetric complications. However, the exact mechanism through which HCQ affects placentation remains u...
Effects of prenatal azithromycin exposure at different stages, doses, and treatment durations on placental development and function in mice [0.03%]
小鼠不同妊娠时期、剂量和疗程的红霉素暴露对胎盘发育和功能的影响
Wen Zhong,Yuting Chen,Xiaomeng Zha et al.
Wen Zhong et al.
Introduction: Azithromycin, a commonly prescribed antibiotic during pregnancy, has raised significant concerns about fetal toxicity. The placenta is essential for fetal growth and development. However, the effects of pren...
Inhalation of titanium dioxide nanoparticles during gestation alters placental bioenergetics in a sex-related manner in rats [0.03%]
妊娠期间吸入二氧化钛纳米粒子以性别相关的方式改变大鼠胎盘生物能量代谢
Talia Seymore,Changjiang Guo,Alyssa Bellomo et al.
Talia Seymore et al.
Introduction: Epidemiological and experimental studies support an association between exposure to particulate matter during pregnancy and the development of fetal growth restriction (FGR). The etiology of FGR is often att...
Placental pathological findings in triplet pregnancies conceived through assisted reproductive technology: a study of 98 cases [0.03%]
辅助生殖技术三胎妊娠胎盘病理改变的临床分析（98例报告）
Eva Manuela Pena-Burgos,María De La Calle,Jose Juan Pozo-Kreilinger et al.
Eva Manuela Pena-Burgos et al.
Introduction: The aim of this study was to determine whether triplet placentas conceived via assisted reproductive technology (ART) present more abnormalities than those conceived in vivo. ...
Comparison of human transplacental transfer of escitalopram, sertraline and paroxetine: an ex vivo cotyledon perfusion study [0.03%]
外源性胎盘绒毛叶灌注研究人乳酸左舍曲林、舍曲林和帕罗西汀的透过性比较研究
Laure-Hélène Préta,Naïm Bouazza,Frantz Foissac et al.
Laure-Hélène Préta et al.
Introduction: Depression is common in pregnant women and the decision to treat must consider potential risk to the fetus. Since data on the transplacental transfer of serotonin reuptake inhibitors (SSRIs) remain sparse, w...
A method for ex vivo human placental Listeria monocytogenes infections [0.03%]
人胎盘外 listeira 核细胞增生症感染的方法
Petra A McLeod,Jagdeep S Ubhi,A Wayne Vogl et al.
Petra A McLeod et al.
Listeriosis is a potentially fatal disease caused by the food-borne pathogen, Listeria monocytogenes. L. monocytogenes has a unique ability to cross epithelial, blood-brain and placental barriers. The specific tropism of L. monocytogenes co...
Patterns of trophoblast migration in deep uterine arteries in accreta placentation [0.03%]
植入性胎盘种植在子宫深部动脉上的滋养层迁移模式
Anna Allen,Carolyn J P Jones,Eric Jauniaux et al.
Anna Allen et al.
Introduction: During normal placentation, extravillous trophoblast (EVT) colonises and, in synergy with maternal leukocytes, transforms the walls of uterine spiral arteries in the decidua and inner myometrium. In placenta...
Achieving multifunctionality in a single, tissue-sized syncytiotrophoblast cell in humans [0.03%]
人类实现单个组织大小的合胞体滋养层细胞多功能性
Madeline M Keenen,Ameya Jalihal,Amy S Gladfelter
Madeline M Keenen
The syncytiotrophoblast (STB) is a tissue-sized multinucleate cell in the human placenta that performs essential functions including molecular transport, metabolism, and hormone production-roles typically distributed across many cell types ...