Test-bench experimental validation of pressure accuracy in a mechanical threshold device for inspiratory muscle training: The threshold IMT® case [0.03%]
机械阈值装置中吸气肌力训练的压力精度测试台实验验证：Threshold IMT示例
Manuele Foschiani,Edoardo Bortolotti,Alberto Chiavone et al.
Manuele Foschiani et al.
Inspiratory muscle training (IMT) is widely used in rehabilitation, yet the accuracy of mechanical threshold devices has been only partially characterised. The aim of this study was to evaluate the validity and stability of the pressure del...
Exhaled acetylcholine in breath condensate as a non-invasive biomarker of asthma control: Insights from patients treated with extrafine single-inhaler triple therapy [0.03%]
呼出气冷凝液中的乙酰胆碱作为评估单吸入器三联疗法治疗哮喘控制情况的无创生物标志物：来自患者的研究数据
Vitaliano Nicola Quaranta,Francesca Montagnolo,Giulia Amoroso et al.
Vitaliano Nicola Quaranta et al.
A substantial proportion of patients with asthma remain uncontrolled despite high-dose ICS/LABA therapy, often due to persistent small-airway dysfunction and heightened cholinergic activation. Acetylcholine (ACh) produced by neuronal and no...
Have pulmonary function testing rates recovered post-COVID-19 pandemic? A population-based study [0.03%]
新冠肺炎疫情后肺功能检查率恢复情况调查——基于人口的队列研究
Javier Silva-Valencia,Karen Tu,Krystle Amog et al.
Javier Silva-Valencia et al.
Background: Pulmonary Function Tests are critical in diagnosing and managing respiratory conditions such as chronic obstructive pulmonary disease and asthma. However, because they generate aerosols, they were restricted i...
Beta-blockers and mortality after myocardial infarction in patients with and without chronic obstructive pulmonary disease - A Danish nationwide cohort study of 96,567 patients [0.03%]
β受体阻滞剂在慢性阻塞性肺疾病患者和非慢性阻塞性肺疾病的急性心肌梗死患者中的疗效差异——一项基于丹麦96567例患者的全国性队列研究
Daniel B Rasmussen,Howraman Meteran,Morten Lamberts et al.
Daniel B Rasmussen et al.
Aims: To investigate the association of beta-blocker use after first-time myocardial infarction (MI) with all-cause mortality and cardiovascular mortality in patients with and without chronic obstructive pulmonary disease...
Changes in peripheral blood leukocyte profiles during elexacaftor/tezacaftor/ivacaftor therapy in cystic fibrosis according to baseline lung function [0.03%]
根据基线肺功能，在囊性纤维化中接受elexacaftor/tezacaftor/ivacaftor治疗期间外周血白细胞谱系的变化规律
Łukasz Pyzia,Tadeusz Francuz,Sylwia Pyzia et al.
Łukasz Pyzia et al.
Background: Cystic fibrosis (CF) is a chronic genetic disease characterised by impaired ion transport, persistent airway inflammation and recurrent respiratory infections. The introduction of CFTR modulators, including el...
Asthma at the crossroads: From anti-TNF-α setbacks to next-generation biologics targeting type 1 and type 2 inflammation [0.03%]
哮喘的十字路口：从抗TNF-α受挫转至下一代生物制剂针对1型和2型炎症
Vaibhavkumar Patel,Nikita Khera,Gurvir Singh et al.
Vaibhavkumar Patel et al.
Severe asthma remains a major unmet clinical challenge due to its marked immunological heterogeneity and the limited efficacy of current therapies in non-Type 2 inflammatory endotypes. Although biologics targeting IL-4, IL-5, and IL-13 have...
Pathological sources of hemoptysis in severe cavitary lung disease: A serial-section study of surgical and autopsy cases [0.03%]
空洞型严重肺疾病的咯血病理来源：外科和尸检病例的连续切片研究
Akira Hebisawa,Hideo Ishikawa,Takashi Nishihara et al.
Akira Hebisawa et al.
Background: The bleeding source in severe hemoptysis associated with cavitary lung disease is often inferred from imaging, but tissue-level evidence remains limited. We aimed to identify pathological bleeding sources and ...
The SAVOIR study: protocol for the development and validation of a PAH knowledge questionnaire [0.03%]
SAVOIR研究：PAH知识问卷的制定与验证方案
Ilma Nascimento,Gabriella Gomes Carvalho,Nathalia Zorze Rossetto et al.
Ilma Nascimento et al.
Background: Pulmonary arterial hypertension (PAH) is a chronic, progressive, and life-threatening disease that requires complex and sustained management. In addition to pharmacological treatment, effective disease control...
Economic analysis of using home mechanical ventilation for children with neuromuscular weakness: the case study from Thailand [0.03%]
泰国儿童神经肌肉无力家庭机械通气经济分析：案例研究
Nattanichcha Kulthanachairojana,Harutai Kamalaporn,Teeradej Kuptanon et al.
Nattanichcha Kulthanachairojana et al.
Neuromuscular Weakness (NMW) is a chronic condition often leading to respiratory failure and the need for long-term ventilatory support. While Home Mechanical Ventilation (HMV) is an alternative to hospital-based mechanical ventilation (MV)...
Respiratory muscle strength and exercise tolerance in older patients with heart failure and preserved or reduced lower-extremity function [0.03%]
射血分数保留或降低的下肢功能障碍老年心力衰竭患者呼吸肌力量和运动耐量的研究
Kanta Iida,Nobuaki Hamazaki,Kentaro Kamiya et al.
Kanta Iida et al.
Introduction: Aside from lower-extremity function, respiratory muscle function may provide complementary information on exercise tolerance in older patients with heart failure (HF). We aimed to clarify the association bet...