Exhaled acetylcholine in breath condensate as a non-invasive biomarker of asthma control: Insights from patients treated with extrafine single-inhaler triple therapy
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A substantial proportion of patients with asthma remain uncontrolled despite high-dose ICS/LABA therapy, often due to persistent small-airway dysfunction and heightened cholinergic activation. Acetylcholine (ACh) produced by neuronal and non-neuronal airway ce... ...