Dose-dependency of a combined EPA:DHA mixture on incorporation, washout, and protein synthesis in C2C12 myotubes [0.03%]
EPA和DHA组合剂量对C2C12肌管摄取、清除和蛋白质合成的影响
M Banic,M van Dijk,F J Dijk et al.
M Banic et al.
We demonstrate divergent incorporation and washout patterns for EPA and DHA following high and low-dose EPA+DHA incubation in C2C12 myotubes, with higher concentrations favoring n-3 PUFA incorporation. Lower n-3 PUFA concentrations increase...
Cross-sectional analysis of plasma n-3 fatty acid levels and self-reported hearing difficulty in the UK Biobank Cohort [0.03%]
英国生物样本库队列中血浆n-3脂肪酸水平与自我报告听力障碍的横断面分析
Michael I McBurney,Nathan L Tintle,Jason Westra et al.
Michael I McBurney et al.
Background: Disabling hearing loss affects ∼430 million people globally. Fish consumption and long-chain n-3 polyunsaturated fatty acid (PUFA) intake were inversely associated with risk of hearing loss, but the associati...
Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation [0.03%]
低级别慢性炎症老年人ω-3脂肪酸衍生脂质介质的性别差异
Jisun So,Jonathan H Yao,Rozana Magadmi et al.
Jisun So et al.
The rate of cardiovascular disease (CVD) death is higher in men than women before age 50 y, but the gap between sexes significantly narrows after menopause. Lipid mediators derived from EPA, DHA and AA play a role in inflammation and CVD. T...
Randomized Controlled Trial
Prostaglandins, leukotrienes, and essential fatty acids. 2024 Apr:203:102655. DOI:10.1016/j.plefa.2024.102655 2024
Impact of polyunsaturated fatty acids during and pregnancy and lactation: A comprehensive review [0.03%]
多不饱和脂肪酸对妊娠和哺乳的影响：全面综述
Yasna Muñoz,Lorena Mercado,Camila Farias et al.
Yasna Muñoz et al.
Background: Docosahexaenoic acid (DHA) and arachidonic acid (ARA) are relevant polyunsaturated fatty acids (PUFA) derived from alpha-linolenic acid (ALA) and linoleic acid (LA), respectively. These are important in pregna...
Blood EPA and DHA status among people living in the United States from 2000 to 2023 [0.03%]
2000—2023年美国居民血液EPA和DHA水平状况
Lea Gründler,Philine Beinhorn,Andreas Hahn et al.
Lea Gründler et al.
Long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs), specifically eicosapentaenoic acid (EPA, C20:5n-3) and docosahexaenoic acid (DHA, C22:6n-3), are well-known for their various health benefits, including cardiovascular and cognitiv...
Resolvin D4 mitigates lipopolysaccharide-induced lung injury in mice [0.03%]
树脂化合物D4通过减轻脂多糖诱导的小鼠肺损伤降低呼吸系统炎症反应研究
Rika Inomata,Hironobu Tsubouchi,Toshifumi Takao et al.
Rika Inomata et al.
Acute respiratory distress syndrome (ARDS) is a life-threatening condition involving severe lung inflammation. The excessive oxidative stress and persistent inflammation that occur in ARDS lead to decreased epithelial integrity and hypoxemi...
The disparate effects of omega-3 PUFAs on intestinal microbial homeostasis in experimental rodents under physiological condition [0.03%]
ω-3多不饱和脂肪酸对生理条件下实验啮齿类动物肠道微生物稳态的异质性影响
Zhenglong Chai,Hui Zhang,Xinyue Ji et al.
Zhenglong Chai et al.
The health benefits of omega-3 polyunsaturated fatty acids (omega-3 PUFAs), primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are linked to their regulatory effects on the composition of the gut microbiota. However, ther...
Omega-3 fatty acids mitigate skin damage caused by ultraviolet-B radiation [0.03%]
欧米加-3脂肪酸可减轻紫外线引起的皮肤损伤
Akiko Harauma,Yui Enomoto,Sayaka Endo et al.
Akiko Harauma et al.
Mice fed a diet containing an adequate amount of ω-3 fatty acids (ω-3 Adq) or a deficient diet (ω-3 Def) were irradiated with ultraviolet-B (UV-B) and were measured daily changes in transepidermal water loss (TEWL). TEWL was significantl...
Gallein but not fluorescein enhances the PGD2-stimulated synthesis of osteoprotegerin and interleukin-6 in osteoblasts: Amplification of osteoprotegerin/interleukin-6 by gallein [0.03%]
棓荧光素而不是萤光素增强PGD2刺激的成骨细胞中osteoprotegerin和白介素-6的合成：棓荧光素放大osteoprotegerin/白介素-6
Tomoyuki Hioki,Gen Kuroyanagi,Rie Matsushima-Nishiwaki et al.
Tomoyuki Hioki et al.
Gallein, a small molecule related to fluorescein, is established as an inhibitor of Gβγ subunits to inhibit G protein (Gs) signaling. This agent is providing a potential therapeutic strategy to ameliorate organ dysfunctions especially inv...