The role of cyclooxygenase-mediated eicosanoids in alcohol-associated liver disease [0.03%]
环氧化酶介导的二十烷酸在酒精相关性肝病中的作用
Weilun Ai,Viswanathan Saraswathi
Weilun Ai
Alcohol-associated liver disease (ALD) is a main health issue worldwide, which is reported as the second leading cause for liver transplantation. Chronic or heavy alcohol use exerts adverse effects on the liver, leading to dysregulated lipi...
Specialized pro-resolving mediators in obesity and overweight conditions: A systematic review of human and animal evidence on comparative differences and associations [0.03%]
肥胖和超重状态下特异的前列腺素 resolves 调解物：系统性回顾人类和动物证据上的差异及关联
Shabnam Shahabi Nejad,Ali Nikparast,Samira Rastgoo et al.
Shabnam Shahabi Nejad et al.
Obesity and overweight are characterized by persistent low-grade inflammation. Specialized pro-resolving mediators (SPMs), polyunsaturated fatty acid-derived metabolites, actively promote inflammatory resolution, and their dysregulation has...
Omega-3 fatty acids and Alzheimer's disease-related brain biomarkers in older adults enriched for preclinical Alzheimer's disease [0.03%]
ω-3脂肪酸和阿尔茨海默病相关脑生物标志物在富含阿尔茨海默病前期的老年人群中的关系
Danielle N Christifano,Emma Kelly,Scott A Sands et al.
Danielle N Christifano et al.
Background: Preclinical and limited human data suggest long-chain omega-3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), may be protective of brain volume and amyloid-beta (Aβ) accumulation, hal...
Vegan multinutrient supplementation significantly increases Omega-3 index and 25-OH-vitamin D status: a randomized, double-blind, placebo-controlled trial in healthy young vegans [0.03%]
一项在健康年轻素食者中关于补充多种营养素显著增加欧米茄-3指数和25-羟基维生素D水平的随机双盲安慰剂对照试验
Tim Zerback,Christian Koeder,Stine Weder et al.
Tim Zerback et al.
In this randomized, double-blind, placebo-controlled trial, 72 healthy vegan adults (aged 19-57 years) received a multinutrient supplement consisting of a vitamin and mineral supplement (providing 26 µg vitamin D) and an omega-3 supplement...
Nina Kahle,Sebastian Kunkel,Selina Böttcher et al.
Nina Kahle et al.
Objective: Intermittent fasting (IF) has emerged as a dietary intervention with potential effects on metabolic health and inflammatory processes. However, clinical evidence for its benefits remains inconsistent, despite n...
Placental abundance of arachidonic acid metabolites is reduced in preterm placentas but is not altered in fetal growth restriction [0.03%]
早产胎盘花生四烯酸代谢物的丰度降低，但胎儿生长受限时没有改变
Stephanie S Chassen,Isabel F Snodgrass,Mairead Dillon et al.
Stephanie S Chassen et al.
Arachidonic acid is a long chain polyunsaturated fatty acid and precursor to bioactive lipid molecules contributing to inflammation and vasoregulation. Placental arachidonic acid metabolites (including oxylipins) are involved in maternal ad...
Cardiovascular safety profile of prostaglandin E and prostacyclin analogues: Clinical reports and ex vivo studies on human coronary arteries [0.03%]
前列腺素E和前列环素类似物的心血管安全性特征：临床报告及人冠状动脉的体外研究
Gaelle Merheb,Heba Abdelazeem,Amira Senbel et al.
Gaelle Merheb et al.
Prostaglandin E1 (PGE1), prostaglandin E2 (PGE2), prostacyclin and their analogues are widely used in clinical practice for their potent biological effects. PGE1/PGE2 analogues, including misoprostol and sulprostone, are primarily used in o...
Specialized pro-resolving mediator (SPM)-enriched supplementation modulates inflammatory biomarkers in patients with symptomatic knee osteoarthritis: Blood plasma analysis from the GAUDI study [0.03%]
来源于GAUDI研究的血浆分析：富含特异性促解决介质（SPM）的补充调节膝骨关节炎患者的炎症生物标志物
Ingrid Möller,Gil Rodas,Jose María Villalón et al.
Ingrid Möller et al.
Background: Osteoarthritis (OA) is a leading cause of chronic pain and functional impairment, associated with persistent inflammation, potentially due to impaired resolution. Specialized pro-resolving lipid mediators (SPM...
Serum fatty acid distributions and prevalence of low omega-3 status in early pregnancy: A cross-sectional analysis of 26,389 samples from an omega-3 test-and-treat program [0.03%]
妊娠早期血清脂肪酸分布和低欧米茄-3状态的流行率：来自一项欧米茄-3检测和治疗项目中26,389份样本的横断面分析
Karen P Best,Robert Gibson,Michael Mugford et al.
Karen P Best et al.
Background: Despite evidence that omega-3 supplementation reduces early preterm birth, population-level data on the distribution of fatty acids in pregnancy are limited. Statewide early-pregnancy screening data were used ...
Association of fish intake with systemic immune-inflammation index: Potential mediating role of n-3 polyunsaturated fatty acids [0.03%]
鱼摄入与全身性免疫炎症指数的关系：n-3多不饱和脂肪酸的潜在中介作用
Shigemasa Tani,Yasuyuki Suzuki,Tsukasa Yagi et al.
Shigemasa Tani et al.
Objective: Low inflammation associated with fish intake may reflect not only the amount of fish consumed but also its nutrient composition and related lifestyle factors. This study investigated the relationship between fi...