Plasma oxylipins in children with sickle cell disease: Associations with biomarkers of inflammation and endothelial activation [0.03%]
患有镰状细胞疾病的儿童的血浆氧脂类：与炎症和内皮激活生物标志物的关联
Bn Yamaja Setty,Krishna Rao Maddipati,Scott W Keith et al.
Bn Yamaja Setty et al.
Oxylipins are polyunsaturated fatty acid (PUFA)-derived inflammatory mediators, and include both pro-inflammatory (prostaglandins, thromboxane, leukotrienes), and pro-resolving (lipoxins, E-resolvins, D-resolvins, protectins, maresins) mole...
Trans 10, cis 12-conjugated linoleic acid alleviates vascular fibrosis in obese mice [0.03%]
全反10，顺12共轭亚油酸减轻肥胖小鼠的血管纤维化
Shuai Yu,Yu Rao,Jiaqi Lu et al.
Shuai Yu et al.
Controlling food intake and improving fat distribution are crucial for preventing and treating cardiovascular disease. Trans-10, cis-12 conjugated linoleic acid (t10c12-CLA) can inhibit fat deposition and facilitate bodyweight reduction, su...
Plasma saturated fatty acids are inversely associated with lean mass and strength in adults: NHANES 2011-2012 [0.03%]
血浆饱和脂肪酸与成年人瘦体质量和力量呈负相关：NHANES 2011-2012 数据集证据
Heitor O Santos,Rafaela Nehme,Larissa S Limirio et al.
Heitor O Santos et al.
Background & aims: Several studies have suggested that increased intake of saturated fatty acids (SFAs) may have a pro-inflammatory effect, potentially impacting muscle mass and strength. However, the relationship of plas...
Effects of seal oil supplementation on lipid profile biomarkers: A systematic review and meta-analysis of randomized controlled trials [0.03%]
海豹油补充对血脂谱生物标志物的影响：随机对照试验的系统评价和荟萃分析
Mariano Gallo Ruelas,Ivo Queiroz,Túlio Pimentel et al.
Mariano Gallo Ruelas et al.
Background: Seal oil (SO) supplementation has been purported to have cardiovascular health benefits due to its content of omega-3 fatty acids; however, the clinical evidence base for this intervention has yet to be compre...
Association between the COX-2 rs689466 polymorphism and antipsychotic treatment: Impact on HDL cholesterol changes in clozapine-treated psychosis patients [0.03%]
COX-2基因多态性与抗精神病治疗的关系：氯氮平治疗精神分裂症患者HDL胆固醇变化的影响
Sergej Nadalin,Ivan Ljoka,Aleksandar Savić et al.
Sergej Nadalin et al.
Several studies have shown antipsychotic effects of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib as an add-on treatment to antipsychotic treatment. The functional rs689466 (A/G) polymorphism in the gene encoding COX-2 (also kn...
Depression and anxiety in the pregnant Omani population in relation to their fatty acid intake and levels [0.03%]
阿曼孕妇抑郁和焦虑与脂肪酸摄入量及水平的关系
Mohammed Al Sinani,Mark Johnson,Michael Crawford et al.
Mohammed Al Sinani et al.
Introduction: Maternal depression during and after pregnancy is a worldwide public concern. Low omega-3 FAs levels and intake in women during pregnancy were associated with a high rate of maternal depression and poor preg...
Long-chain omega-3 polyunsaturated fatty acids are associated with brain connectivity and mood in young adults with subthreshold depression: A preliminary study [0.03%]
长链ω-3多不饱和脂肪酸与轻度抑郁青年大脑连接和情绪的关系：一项初步研究
Paul Faulkner,E Leigh Gibson,Simon C Dyall
Paul Faulkner
Background: The long-chain omega-3 polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have beneficial effects in depression, and these effects may be mediated via changes in fun...
The effect of long-chain n-3 PUFA on liver transcriptome in human obesity [0.03%]
长链n-3多不饱和脂肪酸对人类肥胖肝转录组的影响
Rebeka Joerg,Bianca K Itariu,Melina Amor et al.
Rebeka Joerg et al.
Background and aims: Obesity is associated with a higher risk of severe diseases such as atherosclerotic cardiovascular disease, type 2 diabetes mellitus (T2DM), and metabolic dysfunction-associated steatotic liver diseas...
Brain region and sex-dependent heterogeneity of PUFA/oxylipin profile, microglia morphology and their relationship [0.03%]
大脑区域和性别依赖性的PUFA /氧化脂质异质性、小胶质细胞形态及它们之间的关系
J Geertsema,M A Franßen,F Barban et al.
J Geertsema et al.
Lipid dyshomeostasis and neuroinflammation are key hallmarks of neuropsychiatric and neurodegenerative disorders, including major depressive disorder and Alzheimer's disease. In particular, polyunsaturated fatty acids (PUFAs) and their deri...
Providing lysophosphatidylcholine-bound omega-3 fatty acids increased eicosapentaenoic acid, but not docosahexaenoic acid, in the cortex of mice with the apolipoprotein E3 or E4 allele [0.03%]
提供溶血磷脂酰胆碱结合型欧米伽-3脂肪酸可增加携带载脂蛋白E3或E4等位基因的小鼠皮质中二十碳五烯酸而非二十二碳六烯酸的含量
Bijou Andriambelo,Annick Vachon,Marc-André Dansereau et al.
Bijou Andriambelo et al.
Background: Several mechanisms have been proposed for the brain uptake of omega-3 fatty acids (n-3), including passive diffusion of the unesterified form and the use of Mfsd2a transporter for the lysophosphatidylcholine (...