Sex and dietary ALA and DHA effects on rat heart phospholipase A2 activity mediating fatty acid release and oxylipin formation have cardiovascular implications [0.03%]
性以及饮食中的α-亚麻酸和二十二碳六烯酸对大鼠心脏磷脂酶A2活性的影响，可能对心血管有影响：脂肪酸释放和氧化低密度脂蛋白形成的作用机制研究
Anne Manson,Tanja Winter,Harold M Aukema
Anne Manson
The ways in which diet and sex influence heart phospholipase A2 (PLA2) activities are underexplored, particularly with respect to effects on oxylipin formation. Therefore, male and female Sprague-Dawley rats were provided diets with 1.3 % ...
Dysfunction of COX-2/mPGES-1/PGE2 pathway and EP4 receptor in bronchi from COPD patients [0.03%]
慢性阻塞性肺疾病患者支气管COX-2/mPGES-1/PGE2通路和EP4受体功能障碍
Salma Mani,Zhipeng Li,Hichem Badji et al.
Salma Mani et al.
Progressive airflow obstruction and chronic lung inflammation are hallmarks of chronic obstructive pulmonary disease (COPD). Prostaglandin E2 (PGE2), synthesized by the cyclooxygenase-2 (COX-2) and microsomal prostaglandin E synthase-1 (mPG...
Impact of n-3 polyunsaturate fatty acids supplementation on visual health throughout the life cycle: A systematic review [0.03%]
n-3多不饱和脂肪酸补充剂对生命周期视觉健康的影响：系统性回顾
Claudia Tabilo,Valentina Squella,Paola Illesca et al.
Claudia Tabilo et al.
Introduction: N-3 polyunsaturated fatty acids (n-3 PUFA) are important for mammals and have relevant functions in the body. These fatty acids play an important role in brain development, in the protection of the retina, a...
Fatty acid tissue composition in mice fed diets containing varying levels of Omega-3 fatty acids [0.03%]
不同水平的欧米伽-3不饱和脂肪酸膳食对小鼠组织脂质组成的影响
Nahed Hussein,Irina Dahms,Norman Salem Jr
Nahed Hussein
This study compares varying levels of dietary α-linolenic acid (ALA) as well as eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) on the fatty acid composition of multiple tissues. Two-day pregnant, C57Bl6 mice were fed through g...
Linoleic acid promotes mammary tumor growth and metastasis to brain and lung in female Balb/cJ mice [0.03%]
油酸通过促进乳腺肿瘤生长和向肺、脑转移增加雌性Balb/cJ小鼠的死亡风险
Maria Sanchez-Juarez,Monica Vizcarra-Soto,Rocio Castillo-Sanchez et al.
Maria Sanchez-Juarez et al.
Breast cancer is the leading cause of mortality among women worldwide. The largest prevalence of breast cancer is present in high-income nations, but the incidence in low- to middle-income countries has risen in recent years, which is the c...
Early-life feeding of arachidonic acid and docosahexaenoic acid beneficially modulated ileum and splenocyte oxylipins to support oral tolerance development in allergy-prone BALB/c mice [0.03%]
花生四烯酸和二十碳六烯酸的早期喂养有益地调节了过敏易感BALB/c小鼠口服耐受发育中的回肠和脾细胞氧化脂质体
Ren Wang,Dhruvesh Patel,Susan Goruk et al.
Ren Wang et al.
Background: Early-life feeding of arachidonic acid (ARA)+docosahexaenoic acid (DHA) has been shown to promote immune changes associated with oral tolerance (OT). Oxylipins have been demonstrated to be modulated by diet an...
Association of birth outcomes with maternal and infant FADS1 rs174547 genotypes in Japanese participants [0.03%]
日本受试者中多不饱和脂肪酸代谢基因型与母体及新生儿相关出生结果之间的关联性研究
Reiko Nita,Terue Kawabata,Yasuo Kagawa et al.
Reiko Nita et al.
N-3 long-chain polyunsaturated fatty acids (n-3LCPUFAs) are crucial for child growth and development particularly for fetal growth in utero and brain development and function. This study examined the relationship between birth outcomes and ...
Dihomo-gamma-linolenic acid (DGLA) is inversely related to risk for cardiac death and cardiovascular events during 2 years follow-up after admission for an acute coronary syndrome [0.03%]
二十碳二烯酸（DGLA）与急性冠脉综合征患者两年随访期间心脏死亡和心血管事件的风险呈负相关关系
Dennis W T Nilsen,Hildegunn Aarsetoey,Volker Poenitz et al.
Dennis W T Nilsen et al.
Background/aim: Dihomo-gamma-linolenic acid (DGLA) is derived from linoleic acid. Its presence in red blood cell (RBC) membranes is mainly due to metabolism and not diet. RBC DGLA was negatively associated with all-cause ...
Fatty acid metabolism in the placentae of gestational diabetes mellitus [0.03%]
妊娠糖尿病胎盘脂肪酸代谢的影响及机制研究进展
Nikita Joshi,Sadhana Joshi
Nikita Joshi
The prevalence of gestational diabetes mellitus (GDM), a metabolic complication during pregnancy is increasing rapidly. It exerts various short and long term effects on the mother and the child. Nonetheless, the mechanisms underlying the pa...
HYPOTHESIS: Lipid-protecting disulfide bridges are the missing molecular link between ApoE4 and sporadic Alzheimer's disease in humans [0.03%]
假设：脂质保护性二硫键是ApoE4和人类散发性阿尔茨海默病之间缺失的分子联系
Christopher E Ramsden,Roy G Cutler,Xiufeng Li et al.
Christopher E Ramsden et al.
As the principal lipid transporter in the human brain, apolipoprotein E (ApoE) is tasked with transport and protection of highly vulnerable lipids that are required to support and remodel neuronal membranes, in a process that is dependent o...