An association between PPARα-L162V polymorphism and increased plasma LDL cholesterol levels after risperidone treatment [0.03%]
PPARα-L162V多态性与利培酮治疗后血浆LDL胆固醇水平升高有关联
Sergej Nadalin,Lena Zatković,Vjekoslav Peitl et al.
Sergej Nadalin et al.
Peroxisome proliferator-activated receptor alpha (PPARα) and antipsychotic medications both influence polyunsaturated fatty acids (PUFA) homeostasis, and thus PPARα polymorphism may be linked to antipsychotic treatment response. Here we i...
Subgroup analyses of a randomized trial of DHA supplementation for infants born preterm with assessments of cognitive development up to 7-years of age: What happens in infants born <29 weeks' gestation? [0.03%]
一项针对早产儿的DHA补充随机试验的认知发育评估亚组分析（从出生至7岁）：早产儿发生了什么？
J F Gould,J M Bednarz,T R Sullivan et al.
J F Gould et al.
A recent trial showed that high-dose docosahexaenoic acid (high-DHA) supplementation of infants born
Randomized Controlled Trial
Prostaglandins, leukotrienes, and essential fatty acids. 2023 Dec:198-199:102593. DOI:10.1016/j.plefa.2023.102593 2023
Response to Letter to Editor [0.03%]
致编辑的信的回应
K V Giriraja,S K Bhanagar,L Tomlinson et al.
K V Giriraja et al.
Phospholipase D1 activity is crucial for cytosolic phospholipase A2 -dependent prostaglandin E2 formation in murine osteoblastic MC3T3-E1 cells [0.03%]
磷脂酶D1活性对于小鼠成骨细胞样MC3T3-E1细胞中由胞质型磷脂酶A2依赖性产生的前列腺素E2是必不可少的
Hans Jörg Leis,Werner Windischhofer
Hans Jörg Leis
In bone, prostaglandin E2 (PGE2) is highly osteogenic and formed by osteoblasts, a key modulatory event in the regulation of bone cell activity. MC3T3-E1 cells are widely used as an in vitro model of osteoblast function. It is still not cle...
"Selection of statistical tests influences the interpretation of a study outcome" a comment on "Giriraja KV, Bhatnagar SK, Tomlinson L, Sancilio F. An open-label, multicenter, phase 2 study of a food enriched with docosahexaenoic acid in adults with sickle cell disease. Prostaglandins Leukot Essent Fatty Acids. 2023 Jun; 193:1 [0.03%]
“统计检验的选择会影响研究结果的解读” 对 “Giriraja KV, Bhatnagar SK, Tomlinson L, Sancilio F. 一项关于富含二十二碳六烯酸食物对成人镰状细胞病患者影响的开放标签、多中心2期临床试验。前列腺素白三烯及 essen脂肪酸。2023年6月；193:1-7。” 的评论
Ashwin P Patel
Ashwin P Patel
Parametric tests such as t-tests require a normal distribution of data. However, the determination of normal distribution may not be conclusive while dealing with a small sample size. Non-parametric tests such as Wilcoxon tests may be used ...
Decreased plasma levels of sphingolipids and total cholesterol in adult cystic fibrosis patients [0.03%]
囊性纤维化患者血浆鞘脂和总胆固醇水平降低
Dilara Bal Topcu,Berrin Er,Filiz Ozcan et al.
Dilara Bal Topcu et al.
Background: Sphingolipid species in the lung epithelium have a critical role for continuity of membrane structure, vesicular transport, and cell survival. Sphingolipid species were reported to have a role in the inflammat...
15-lipoxygenase and cyclooxygenase expression profile and their related modulators in COVID-19 infection [0.03%]
Covid-19感染中的15-LOX和COX表达谱及其相关调节剂
Sara Kianfar,Vahid Salimi,Alireza Jahangirifard et al.
Sara Kianfar et al.
Background: The role of the lipoxygenase (LOX) and cyclooxygenase (COX) enzymes in maintaining cellular homeostasis and regulating immune responses promoted us in this study to analyze the pattern of changes in 15-lipoxyg...
Effect of maternal fish oil supplementation during lactation on socioemotional wellbeing and physical activity in 13-year-old children: A randomized clinical trial [0.03%]
母体哺乳期补充鱼油对13岁儿童社交情绪健康和身体活动的影响：一项随机临床试验
Lotte Lauritzen,Emilie R Hegelund,Sara E Eriksen et al.
Lotte Lauritzen et al.
Early dietary long-chain n-3PUFA (n-3LCPUFA) may affect brain development. We investigated if fish oil supplementation of lactating mothers affected socioemotional wellbeing in adolescents in a potentially gender-specific manner. At age 13,...
Resolvin E1 heals injured cardiomyocytes: Therapeutic implications and H-FABP as a readout for cardiovascular disease & systemic inflammation [0.03%]
_resolution E1修复损伤的心肌细胞：治疗意义及H-FABP作为心血管疾病和全身性炎症的标志物_
A Zheng,N Huang,D Bean et al.
A Zheng et al.
The purpose of this study is to investigate heart-fatty acid binding protein (H-FABP) leakage from cardiomyocytes as a quantitative measure of cell membrane damage and to test healing by Resolvin E1 (RVE1) as a potential therapeutic for pat...
Tumor microenvironment-derived monoacylglycerol lipase provokes tumor-specific immune responses and lipid profiles [0.03%]
肿瘤微环境衍生的单酰基甘油脂酶引发肿瘤特异性免疫反应和脂质谱型
Eva Gruden,Melanie Kienzl,Carina Hasenoehrl et al.
Eva Gruden et al.
We recently described that monoacylglycerol lipase (MGL) is present in the tumor microenvironment (TME), increasing tumor growth. In this study we compare the implications of MGL deficiency in the TME in different tumor types. We show that ...