Higher Nodal expression is often associated with poorer survival in patients diagnosed with melanoma and treated with anti-PD1 therapy [0.03%]
Nodal表达较高往往与接受抗PD1治疗的黑色素瘤患者的预后较差相关
Philippe D Gascard,Xianhong Wang,Mehdi Nosrati et al.
Philippe D Gascard et al.
Advanced melanoma is considered the most aggressive and deadly form of skin cancer whose incidence has been rising over the past three decades. In the absence of treatment, the median overall survival for advanced-stage metastatic disease i...
Feasibility of indocyanine green (ICG) fluorescence in ex vivo pathological dissection of colorectal lymph nodes-a pilot study [0.03%]
吲哚菁绿(ICG)荧光在外科病理中用于结直肠淋巴结分离的可行性-一项初步研究
Lorand Lakatos,Ildiko Illyes,Andras Budai et al.
Lorand Lakatos et al.
Accurate lymph node (LN) retrieval during colorectal carcinoma resection is pivotal for precise N-staging and the determination of adjuvant therapy. Current guidelines recommend the examination of at least 12 mesocolic or mesorectal lymph n...
Semi-automated analysis of HER2 immunohistochemistry in invasive breast carcinoma using whole slide images: utility for interpretation in clinical practice [0.03%]
使用整个载玻片图像对侵袭性乳腺癌HER2免疫组化进行半自动分析:在临床实践中的应用价值
Chiu-Hsiang Connie Liao,Nilay Bakoglu,Emine Cesmecioglu et al.
Chiu-Hsiang Connie Liao et al.
Human epidermal growth factor receptor 2 (HER2) gene amplification and subsequent protein overexpression is a strong prognostic and predictive biomarker in invasive breast carcinoma (IBC). ASCO/CAP recommended tests for HER2 assessment incl...
Diagnostic challenges in patients with Castleman disease, a single center experience from Hungary [0.03%]
匈牙利一家医疗中心Castleman病诊断挑战的单中心经验
Boglárka Brúgós,Zsófia Simon,Gábor Méhes et al.
Boglárka Brúgós et al.
Castleman disease is a rare and atypical lymphoproliferative disorder characterized by diverse clinical manifestations. It has both unicentric and multicentric forms, the latter with further subdivisions, i.e., human herpesvirus 8-associate...
G protein-coupled estrogen receptor 1 and collagen XVII endodomain expression in human cutaneous melanomas: can they serve as prognostic factors? [0.03%]
人皮肤黑色素瘤中的G蛋白偶联雌激素受体1和胶原XVII内域表达:它们能否作为预后因素?
Uğur Çakır,Petra Balogh,Anikó Ferenczik et al.
Uğur Çakır et al.
Melanoma incidence is increasing globally. Although novel therapies have improved the survival of primary melanoma patients over the past decade, the overall survival rate for metastatic melanoma remains low. In addition to traditional prog...
Molecular classification of endometrial cancer: preliminary experience from a single Portuguese academic center [0.03%]
子宫内膜癌的分子分型:葡萄牙单中心初步经验
João Casanova,Ana G da Costa,Ana Pestana Lopes et al.
João Casanova et al.
Background: Since the seminal publication of the TCGA consortium in 2013, the molecular classification of endometrial cancer has been widely accepted as a new and powerful tool to better understand the natural history of ...
Case report: A mesenchymal chondrosarcoma with alternative HEY1::NCOA2 fusions in the sella turcica [0.03%]
个例报告:蝶鞍区发生HEY1::NCOA2变异的软骨肉瘤一例
Satsuki Kishikawa,Akihide Kondo,Takashi Yao et al.
Satsuki Kishikawa et al.
Introduction: Mesenchymal chondrosarcoma (MCS) is a rare subtype of chondrosarcoma that occurs at widespread anatomical locations, such as bone, soft tissue, and intracranial sites. The central nervous system (CNS) is one...
Intraoperative pyloric drainage is unnecessary during esophagectomies: a meta-analysis and systematic review of randomized controlled trials [0.03%]
食管切除术中幽门引流的系统评价和meta分析研究
Armand Csontos,Dávid Németh,Lajos Szakó et al.
Armand Csontos et al.
Objective: The topic of this meta-analysis is the comparison of gastric conduit esophageal reconstructions with or without pyloroplasty. Background: Surgical procedures, especially minimal invasive esophagectomy (MIE) can be a curative trea...
Molecular genetic investigation of hereditary breast and ovarian cancer patients in the Southern Transdanubian region: widening the mutation spectrum and searching for new pathogenic variants using next-generation methods [0.03%]
匈牙利南部-transdanube地区遗传性乳腺癌和卵巢癌患者的分子基因研究:使用下一代方法扩大突变谱并寻找新的致病变异
László Baráti,Anita Maász,Alexandra Mikó et al.
László Baráti et al.
Hereditary breast and ovarian cancer is a well-known genetic condition, inherited mainly in an autosomal dominant way, which elevates the risk of developing malignancies at a young age in heterozygous carriers. Advances in new generation se...
The efficacy and safety of second salvage autologous transplantation in myeloma patients [0.03%]
复发性多发性骨髓瘤患者自体造血干细胞第二次挽救移植的疗效及安全性分析
Reka Rahel Bicsko,Renata Nyilas,Robert Szasz et al.
Reka Rahel Bicsko et al.
Despite the availability of many novel therapies for multiple myeloma, it remains an incurable disease with relapse fated in almost all patients. In the era of modern agents, second autologous stem cell transplantation still holds its role ...