Conjunctival melanoma: comprehensive insights into clinical features, genetic alterations, and modern treatment approaches [0.03%]
结膜黑色素瘤：临床特征、基因改变及现代治疗手段的全面见解
Snježana Kaštelan,Danijela Mrazovac Zimak,Luka Ivić et al.
Snježana Kaštelan et al.
Conjunctival melanoma (CoM) is a rare and aggressive ocular surface malignancy, characterised by increasing incidence, clinical complexity, and substantial challenges in diagnosis and treatment. This review consolidates current knowledge on...
Application of TRPS1 in ER-negative or low expression distant metastatic breast carcinoma [0.03%]
TRPS1在雌激素受体阴性或低表达的乳腺癌远处转移中的应用研究
Runze Zhang,Jing Liu,Lei Jiang et al.
Runze Zhang et al.
Purpose: Traditional markers have various limitations in recognizing the breast origin of distant metastatic breast carcinoma (DMBC), especially in ER-negative or low expression cases. In recent years, TRPS1 has been repo...
Gabriella Gálffy,Réka Hécz,Réka Bujdosó et al.
Gabriella Gálffy et al.
This study provides a comprehensive analysis of early-stage resectable non-small cell lung cancer (NSCLC) in Hungary, investigating incidence rates, demographic trends, treatment patterns and survival outcomes. We used data from the Nationa...
MtDNA copy number enrichment is associated with poor prognosis and eosinophilic morphology in clear cell renal cell carcinoma [0.03%]
细胞丰度与透明细胞肾细胞癌不良预后及嗜酸性形态有关
Sarah Bellal,Cyrielle Rolley,Jeremy Richard et al.
Sarah Bellal et al.
Clear cell renal cell carcinoma (ccRCC) is the most common renal malignancy. However, the combined clinical and biological scores commonly used to predict the clinical outcome are imperfect and need improvement. The main goal of our study w...
Diagnostic challenges of rarely well-differentiated adenocarcinoma of the stomach [0.03%]
胃分化良好腺癌的诊断挑战
Tian Qin,Yong Wang,Zebin Xiao et al.
Tian Qin et al.
Background: Fundic gland tumors are a rare subtype of gastric tumors with fundic gland differentiation. This group of tumors has a low incidence rate and shows indistinctive cellular atypia, obvious structural atypia, spe...
Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition - the potential cause of occupational Bisphenol-A exposition [0.03%]
病例报告：有毒的肾小管间质性肾病伴脂褐素沉积-职业型双酚A暴露的潜在原因
László Bidiga,Tamás Csonka,Gábor Méhes et al.
László Bidiga et al.
This case study delves into the link, between exposure to Bisphenol A (BPA) and kidney issues filling a gap in human focused research found in studies. The individual, a 72-year man with a history of BPA exposure in a plastics manufacturing...
The implications of abnormal signal patterns of break-apart FISH probes used in the diagnosis of bone and soft tissue tumours [0.03%]
断信号的断裂型FISH探针在骨和软组织肿瘤诊断中的意义
Hongtao Ye,Fitim Berisha,Evie Rowles et al.
Hongtao Ye et al.
Many subtypes of bone and soft tissue tumours harbour specific chromosome translocations leading to chimeric fusion genes. The identification of these specific fusion genes is the basis of molecular diagnoses in such tumours. Break-apart FI...
Novel FRMD6::PTH chimera in tumorous bone lesion carrying a t(4;11;14;12)(q35;p15;q22;q13) [0.03%]
携带染色体易位t(4;11;14;12)(q35;p15;q22;q13)的肿瘤性骨病变中的新型FRMD6::PTH嵌合蛋白
Ioannis Panagopoulos,Kristin Andersen,Isabel Lloret et al.
Ioannis Panagopoulos et al.
Background: Benign fibro-osseous lesions are characterized by the replacement of normal bone with cellular fibrous connective tissue with new bone formation. The published cytogenetic information on these tumors is limite...
Low-grade oncocytic tumor of the kidney-a clinical, pathological, and next generation sequencing-based study of 20 tumors [0.03%]
肾脏低级别乳头样肾细胞癌的临床、病理及基于下一代测序的研究(20例报告)
Alex Jenei,Boglárka Pósfai,Borbála Dénes et al.
Alex Jenei et al.
Low-grade oncocytic tumor (LOT) of the kidney is a recently recognized renal neoplasm with distinctive morphologic, immunophenotypic, and molecular features that distinguish it from other eosinophilic tumors such as oncocytoma and chromopho...
Comparison of intraoperative frozen section consultation and hysterectomy characteristics in patients diagnosed with EIN in endometrial biopsies [0.03%]
子宫内膜不典型增生患者的术中快速病理检查与子宫切除病理特征的对比分析
Hasan Volkan Ege,Bilal Esat Temiz,Alp Usubutun et al.
Hasan Volkan Ege et al.
Objective: This study aimed to assess the likelihood of detecting cancer in final pathology and evaluate the accuracy of intraoperative frozen-section assessment in cases of endometrioid intraepithelial neoplasia (EIN). ...