Synergistic changes in bystander CD8 and conventional CD4 T cells during neoadjuvant chemoimmunotherapy for non-small cell lung cancer reveal treatment response [0.03%]
新辅助化疗免疫治疗期间旁观者CD8和传统CD4T细胞的协同变化揭示了治疗反应
Li Wu,Liying Yang,Jian Sun et al.
Li Wu et al.
Objective: We analyzed changes in intratumoral CD8+ and CD4+ T-cell subpopulations following neoadjuvant chemoimmunotherapy in non-small cell lung cancer. We then assessed whether these alterations favored better outcomes...
Case Report: From teratoma to adenocarcinoma: molecular insights into somatic-type malignancy in testicular germ cell tumors - two case reports and review of the literature [0.03%]
病例报告：从畸胎瘤到腺癌：对睾丸生殖细胞肿瘤中体细胞类型恶性肿瘤的分子见解-两例报道及文献综述
Tímea Rozsvai,Boglárka Pósfai,László Torday et al.
Tímea Rozsvai et al.
Testicular germ cell tumors (TGCTs), though typically responsive to therapy, may rarely develop somatic-type malignancy (STM), a transformation associated with poor prognosis and chemoresistance. This study presents two cases of postpuberta...
Circulating tumor cells: indicators of cancer progression, plasticity and utility for therapies [0.03%]
循环肿瘤细胞：提示癌症进展、可塑性和治疗用途的指标
Tamás Richárd Linkner,Zsófia Brigitta Nagy,Alexandra Kalmár et al.
Tamás Richárd Linkner et al.
Cancer is a deadly disease affecting millions of people worldwide. Circulating tumor cells (CTCs) represent a critical link between primary malignancies and metastasis, acting as key players in cancer dissemination, progression, and recurre...
Two B or not two B; the question of bendamustine dosing in low grade lymphoma [0.03%]
来那度胺与利妥昔单抗联合治疗复发/难治滤泡性淋巴瘤患者：II 期研究结果
Eszter Földi,Ádám Wiedemann,Szabolcs Svorenj et al.
Eszter Földi et al.
Background: Follicular lymphoma (FL) is an indolent yet incurable B-cell lymphoma subtype commonly treated with a combination of bendamustine and anti-CD20 antibodies such as rituximab. While the standard administration i...
Modelling metastasis in a dish: in vitro approaches for studying breast cancer progression [0.03%]
体外模型在乳腺癌转移中的应用及进展研究
Irem Duman,Verena Pichler
Irem Duman
Cancer metastasis, driven by cell migration, remains the leading cause of cancer-related deaths. In breast cancer, its high metastatic potential underscores the need for better preclinical models to bridge the gap between laboratory finding...
The prognostic potential of circulating biomarkers for sarcoma patients with pleural dissemination [0.03%]
循环生物标志物对肉瘤患者胸膜转移的预后价值
Hannah Schwab,Stéphane Collaud,Sebastian Bauer et al.
Hannah Schwab et al.
Sarcomas are a heterogeneous group of rare and aggressive malignancies and have a propensity to metastasize to the thoracic cavity. While sarcoma lung metastasectomy is an established modality, only scarce information is available about pot...
Ali Al Khader,Christian Seghetti,Fatine Oumlil et al.
Ali Al Khader et al.
Recognition of unusual histological features can augment and hasten a diagnosis but also stimulate ideas about physiological and pathological cellular interactions. Osteoclasts resorb mineralised tissue and therefore can be found at sites o...
Relationship between qualitative and quantitative parameters of three-dimensional computed tomography, EGFR gene mutation, and ALK gene rearrangement in GGO-associated lung adenocarcinoma and their prognostic value [0.03%]
肺腺癌磨玻璃成分定性及定量参数与EGFR基因突变和ALK重排的关系及其预后价值
Xinyan Liu,Yi Ren,Zihang Fei et al.
Xinyan Liu et al.
Objective: We aimed to analyze the relationship between the quantitative and qualitative parameters of three-dimensional computed tomography (CT), epidermal growth factor receptor (EGFR), and anaplastic lymphoma kinase (A...
Case Report: Genomic profiling in an invasive solid papillary carcinoma patient with liver metastasis and a history of invasive lobular carcinoma [0.03%]
病例报告：肝转移实性乳头状癌患者的基因组谱分析及浸润性小叶癌病史
Xuan Wang,Feng Zhu,Hui Wang et al.
Xuan Wang et al.
Introduction: Solid papillary carcinoma (SPC) is a rare type of breast cancer that accounts for approximately 1% of all breast cancers. Although SPC is considered an indolent tumor, metastasis occurs in a few cases. The b...
B7-H3: a consistent marker in metastatic colorectal cancer with potential for targeted treatment [0.03%]
B7-H3在转移性结直肠癌中的一致性标志及其潜在治疗靶点作用
Julia M Ott,Verena Gassenmaier,Michael Bitzer et al.
Julia M Ott et al.
Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide. Despite advances in various treatment approaches, outcomes for patients with metastatic CRC (mCRC) remain poor, and treatment-associated si...