The Histone Acetylation Modifications of Breast Cancer and their Therapeutic Implications [0.03%]
乳腺癌组蛋白乙酰化修饰及治疗意义研究进展
Pingping Guo,Wenqi Chen,Huiyu Li et al.
Pingping Guo et al.
The histone acetylation modifications (HAMs) influence a large number of cellular functions. They are mediated through histone acetyltransferase (HAT) and histone deacetylase (HDAC). Nowadays, people have realized that HAMs are crucial for ...
IL-2 And IL-15 Induced NKG2D, CD158a and CD158b Expression on T, NKT- like and NK Cell Lymphocyte Subsets from Regional Lymph Nodes of Melanoma Patients [0.03%]
细胞因子IL-2和IL-15对肿瘤引流淋巴结中T、类NK-T和NK细胞上NKG2D、CD158a和CD158b表达的诱导作用
Ana Vuletić,Irena Jovanić,Vladimir Jurišić et al.
Ana Vuletić et al.
Regional lymph nodes (LN)s represent important immunological barriers in spreading of malignant tumors. However, they are the most frequent early metastatic site in melanoma. Immunomodulatory agents including cytokines have been included in...
High-level Sp1 is Associated with Proliferation, Invasion, and Poor Prognosis in Astrocytoma [0.03%]
高Sp1与 astrocytoma 的增殖、侵袭和不良预后有关
Yi-Ting Chen,Hung-Pei Tsai,Chun-Chieh Wu et al.
Yi-Ting Chen et al.
Astrocytoma is the most common and the most lethal primary brain tumor in adults. Grade IV glioblastoma is usually refractory to currently available surgical, chemotherapeutic, and radiotherapeutic treatments. The Specificity protein 1 (Sp1...
Recent advances of Blood telomere length (BTL) shortening: A potential biomarker for development of cancer [0.03%]
近期血液端粒缩短的最新研究进展：癌症发展的潜在生物标志物
Paramita Mandal
Paramita Mandal
Telomeres, the specific DNA-protein structures remains at both ends of each chromosome and are crucial in the maintenance of chromosome integrity and genomic stability with protection of the chromosome from damage and degradation.. Increasi...
Transforming Growth Factor Beta 2 Inhibits Growth and Proliferation Potential of Smad4 and p53 Mutated Human Colon Adenocarcinoma Cells [0.03%]
转化生长因子β2通过Smad4和p53突变抑制人结肠腺癌细胞的生长和增值潜能
Ramamoorthi Ganesan,Nageswaran Sivalingam
Ramamoorthi Ganesan
Toshiyuki Ishiwata,Yoko Matsuda,Hisashi Yoshimura et al.
Toshiyuki Ishiwata et al.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high incidence of distant metastasis and recurrence. Cancer stem cells (CSCs), which are pluripotent, self-renewable, and capable of forming tumors, contribute to PD...
Correction to: Comparison of the Amplification Refractory Mutation System, Super Amplification Refractory Mutation System, and Droplet Digital PCR for T790 M Mutation Detection in Non-small Cell Lung Cancer after Failure of Tyrosine Kinase Inhibitor Treatment [0.03%]
纠正：酪氨酸激酶抑制剂治疗失败后的非小细胞肺癌T790 M突变检测中扩增抗拒型基因突变系统、超级扩增抗拒型基因突变系统和液滴数字pcr的比较纠正：酪氨酸激酶抑制剂治疗失败后的非小细胞肺癌T790 M突变检测中扩增抗拒型基因突变系统、超级扩增抗拒型基因突变系统和液滴数字PCR的比较
Lucheng Zhu,Shirong Zhang,Yanping Xun et al.
Lucheng Zhu et al.
The affiliation of first author (Lucheng Zhu) should be Department of Oncology, Hangzhou Cancer Hospital and Department of Oncology, Hangzhou First People's Hospital, Nanjing Medical University.
Published Erratum
Pathology oncology research : POR. 2018 Oct;24(4):951. DOI:10.1007/s12253-018-0421-9 2018
Identification of miR-146a is Associated with the Aggressiveness and Suppresses Proliferation via Targeting CDKN2A in Breast Cancer [0.03%]
miR-146a的鉴定与侵袭性相关并通过靶向CDKN2A抑制乳腺癌增殖
Yanping Zhang,Shi Ding,Jie Yang et al.
Yanping Zhang et al.
There is emerging evidence that some microRNAs can promote or suppress several human cancer development and progression. However, the profile and molecular mechanism of microRNAs for human breast cancer is poorly unknown. We used bioinforma...
Prone Positioning on a Belly Board Decreases Rectal and Bowel Doses in Pelvic Intensity-Modulated Radiation Therapy (IMRT) for Prostate Cancer [0.03%]
俯卧位放疗可降低前列腺癌盆腔调强放疗(IMRT)的直肠和小肠受量
Renáta Kószó,Linda Varga,Emese Fodor et al.
Renáta Kószó et al.
The presence of normal tissues in the irradiated volume limits dose escalation during pelvic radiotherapy (RT) for prostate cancer. Supine and prone positions on a belly board were compared by analyzing the exposure of organs at risk (OARs)...
The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells [0.03%]
不同mTOR抑制剂对EGFR抑制剂耐药的结直肠癌细胞的影响
Tamás Sticz,Anna Molnár,Titanilla Dankó et al.
Tamás Sticz et al.
Several monoclonal antibodies and inhibitors targeting signalling pathways are being used in personalised medicine. Anti-EGFR antibodies seem to be effective, however, therapy resistance often occurs in colon carcinoma cases. mTOR inhibitor...