Urmi Ghone,Gargi S Sarode,Namrata Sengupta et al.
Urmi Ghone et al.
Soft substrate stiffness modifies corneal epithelial stem cell phenotype through hippo-YAP/notch pathway crosstalk [0.03%]
软基底刚性通过hippo-YAP/notch通路串扰改变角膜上皮干细胞表型
Qi Pu,Qian Ma,Jing Li et al.
Qi Pu et al.
Corneal disease remains to be one of the leading causes of blindness in the world and limbal stem cell (LSC) therapy is a promising therapy for LSC deficiency, which is associated with the diseased corneal epithelium repair. Soft substrate ...
Rise and exacerbation of oral lichen planus in the background of SARS-CoV-2 infection [0.03%]
SARS-CoV-2感染背景下口腔扁平苔藓的发作与恶化
Anubhuti Sood,Sreevatsan Raghavan,Puneet Batra et al.
Anubhuti Sood et al.
Oral Lichen Planus (OLP) is a chronic inflammatory disorder whose exact etiology remains unknown. Inflammatory mediators, cytotoxic CD8+ T cells and mast cells have been hypothesized to mediate the pathogenesis of OLP. COVID-19 pandemic cau...
Systemic cytology. A novel diagnostic approach for assessment of early systemic disease [0.03%]
系统细胞学。评估早期全身性疾病的新诊断方法
Stefan Schreier,Wannapong Triampo
Stefan Schreier
Recognition of low grade or asymptomatic systemic diseases suggests prevention of the worst, yet has been proven challenging ever since. Biomarker-based liquid biopsy has emerged in recent years as a practical platform for the assessment of...
Transient Receptor Potential Vanilloid 1 (TRPV1) as a plausible novel therapeutic target for treating neurological complications in ZikaVirus [0.03%]
瞬时受体电位香草酸亚型1(TRPV1)作为治疗寨卡病毒神经并发症的新型潜在治疗靶点
Ranjana Bhandari,Reetrakshi Gupta,Anushka Vashishth et al.
Ranjana Bhandari et al.
Zika virus was declared a national emergency by WHO (World Health Organization) in 2016 when its widespread outbreaks and life-threatening complications were reported, especially in newborns and adults. Numerous studies reported that neuroi...
Mucus targeting as a plausible approach to improve lung function in COVID-19 patients [0.03%]
粘液定位可能是改善COVID-19患者肺功能的合理方法
Sarath S Kumar,Aiswarya Binu,Aswathy R Devan et al.
Sarath S Kumar et al.
COVID-19 (SARS-CoV-2) has emerged as one of the worst pandemics that have tormented the globe due to its highly contagious nature. Even if the disease manifests fever-like symptoms mostly, the disease may progress to the pulmonary-hyper inf...
Is digital necrosis in COVID-19 caused by neutrophil extracellular traps: Potential therapeutic strategies [0.03%]
COVID-19中的数字坏死是否由中性粒细胞外陷阱引起:可能的治疗策略
Marian Simka
Marian Simka
Some of the COVID-19 patients present with ischemic lesions of their finger and toes. Standard anticoagulant therapy is usually unsuccessful for the treatment of this unique presentation of COVID-19. In this review current evidence is prese...
Receptor based virtual screening of potential novel inhibitors of tigar [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator [0.03%]
基于受体的虚拟筛选潜在新型抑制剂的tigar [TP53(肿瘤蛋白53)诱导的糖酵解和凋亡调节因子]
Jagadeesha Poyya,D Jagadeesha Kumar,H G Nagendra et al.
Jagadeesha Poyya et al.
TP53 (tumor protein 53)-induced glycolysis and apoptosis regulator (TIGAR) belongs to the phosphatases family of proteins that modulates the level of reactive oxygen species in tumor cells. This protein plays a vital role as a negative regu...
Lin Shen,Dongqiang Liu,Yan Huang
Lin Shen
Schizophrenia is a severe mental disease involving both neurological and psychiatric abnormalities. Previous studies mainly focus on damage to high-order cognitive dysfunction, which is related to high-level cortical regions such as the pre...
Estimate of benefit attributable to wearing masks in Chicago during the early days of the pandemic [0.03%]
疫情期间早期在芝加哥戴口罩获益的估算
Damien G Retzinger,Andrew C Retzinger,Gregory S Retzinger
Damien G Retzinger