The Role of Hemispheric Sensory Shifts: Impacts on Stretch Reflex and Motor Plasticity Post-Stroke [0.03%]
半球感觉转移在脑卒中后牵张反射和运动塑性中的作用
Mahmood Rajabtabar Darvish,Joohwan Sung,Jordan N Williamson et al.
Mahmood Rajabtabar Darvish et al.
Previous studies have found that post-stroke motor impairments are associated with damage to the lesioned corticospinal tract and the hyperexcitability of the cortico-reticulospinal tract at the hemisphere opposite to the lesion side, i.e.,...
Neuron-Targeted Exosome Therapy: A Novel Approach for Treating Cardiogenic Dementia via RyR2 Inhibition [0.03%]
神经靶向外泌体治疗：通过 RyR2 抑制治疗心源性痴呆的新方法
Richa Saxena,Yaoliang Tang
Richa Saxena
Cardiogenic dementia (CD), recognized since the late 1970s, manifests as altered consciousness and cognition due to heart conditions. Its elusive molecular mechanisms present diagnostic and management challenges. Emerging research implicate...
How the Somatosensory System Adapts to the Motor Change in Stroke: A Hemispheric Shift? [0.03%]
缺血性卒中后躯体感觉系统向对侧半球的转换吗？
Jordan N Williamson,Beni Mulyana,Rita Huan-Ting Peng et al.
Jordan N Williamson et al.
Previous studies found that post-stroke motor impairments are associated with damage to the lesioned corticospinal tract and a maladaptive increase in indirect contralesional motor pathways. How the somatosensory system adapts to the change...
J F Meschia,B K Lal,R M Lazar et al.
J F Meschia et al.
While many risk factors are modifiable, there remains a compelling need for novel approaches to prevent cognitive impairment. We propose that unstable carotid plaque causes microemboli that, in turn, cause microinfarcts and other adverse pa...
Is Epstein Barr virus latency protective against type 1 diabetes? [0.03%]
Epstein-Barr病毒潜伏期对1型糖尿病有保护作用吗？
Magdalena Zoledziewska
Magdalena Zoledziewska
Elevated Circulating Procathepsin L as a Potential Biomarker of Inflamm-aging [0.03%]
高循环前猫尿肽L作为炎症衰老的潜在生物标志物
Cassie Shu Zhu,Weiqiang Chen,Xiaoling Qiang et al.
Cassie Shu Zhu et al.
Inflamm-aging is a condition of low-grade and chronic systemic inflammation characterized by a systemic increase in multiple inflammatory biomarkers such as tumor necrosis factor (TNF), interleukin 6 (IL-6), C-reactive protein (CRP), and CX...
Potential Therapeutic Targets for Hypotension in Duchenne Muscular Dystrophy [0.03%]
杜氏肌营养不良症低血压的潜在治疗靶点
Harshi Saxena,Neal L Weintraub,Yaoliang Tang
Harshi Saxena
Duchenne Muscular Dystrophy (DMD) is marked by genetic mutations occurring in the DMD gene, which is widely expressed in the cardiovascular system. In addition to developing cardiomyopathy, patients with DMD have been reported to be suscept...
Reprogramming endothelial and vascular smooth muscle cells to prevent and treat hypertension [0.03%]
内皮细胞和血管平滑肌细胞重编程防治高血压的研究
Laena Pernomian,Wenbin Tan,Cameron McCarthy et al.
Laena Pernomian et al.
The major pathophysiological characteristic of hypertension is the occurrence of small artery remodeling and endothelial dysfunction. There is also solid evidence showing that microcirculation abnormalities occur prior to the onset of hyper...
Cje Metcalf,S L Klein,J M Read et al.
Cje Metcalf et al.
Antibodies are a core element of the immune system's defense against infectious diseases. We hypothesize that antibody titres might therefore be an important predictor of survival in older individuals. This is important because biomarkers t...
Will the increased use of ring lights during the coronavirus pandemic lead to a growing burden of macular degeneration? [0.03%]
新型冠状病毒肺炎疫情期间环形灯的使用增加会导致年龄相关性黄斑变性的发病率升高吗？
Jessica Stanhope,Philip Weinstein
Jessica Stanhope
The pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), has brought with it many changes in the way with live, work, and socialise. One such change is an i...