Tyler Alexander Cookson
Tyler Alexander Cookson
As bacteriophage therapy is being investigated more as an alternative to antibiotics, laboratories are isolating and characterizing the functions of bacteriophages. Additionally, with large variations between gut microbiome studies and inco...
The oncoprotective fever hypothesis: Have antibiotics, antimalarials and antipyrectics contributed to the global rise in cancer over the past century? [0.03%]
抗癌保护性发热假说：在过去的一个世纪里，抗生素，抗疟疾药和退烧药促使了全球癌症发病率的上升吗？
S Braude,J Varghese
S Braude
The adaptive and therapeutic nature of fever has been recognized for centuries and both local and systemic thermotherapy are now used to enhance the effectiveness of both chemotherapy and radiation therapy for cancer. We propose that the su...
Deficient synthesis of melatonin in COVID-19 can impair the resistance of coronavirus patients to mucormycosis [0.03%]
COVID-19中褪黑激素合成不足会削弱冠状病毒患者对毛霉菌病的抵抗力
Amarnath Sen
Amarnath Sen
In addition to uncontrolled diabetes and the excess use of corticosteroids, it is believed that other factors may be responsible for the recent spurt of COVID-19 associated mucormycosis (CAM). In the present paper it is argued that COVID-19...
Histone deacetylase inhibition improves metabolism and mitochondrial dynamics: A potential novel therapeutic strategy for sarcopenia coexisting with diabetes mellitus [0.03%]
组蛋白去乙酰化酶抑制剂改善代谢和线粒体动力学：可能是糖尿病共存肌少症的一种潜在新型治疗策略
Ting-Wei Lee,Han-Wen Liu,Yuan-Feng Lin et al.
Ting-Wei Lee et al.
Sarcopenia, the age-associated-fragility with loss of skeletal muscle mass and function, often coexists with type 2 diabetes (T2D) in older individuals. Derangement of muscle metabolism and mitochondrial dynamics is critical, particularly i...
Is there a relationship between neural EGFL like 1 (NELL1) promoter hypermethylation and prognosis of gastric cancer? [0.03%]
神经递质EGFL类似物1（NELL1）的启动子高甲基化与胃癌预后有关吗？
Changlu Gao,Haibin Liu,Yubo Zhao et al.
Changlu Gao et al.
We hypothesized that neural EGFL like 1 (NELL1) promoter hypermethylation might be associated with the prognosis of gastric cancer. Some studies considered NELL1 as a tumor suppressor gene and our research confirmed for the first time the h...
Phenylboronic acid modified lipid nanocarriers mediated co-delivery of immunocytokine TRAIL and gamma-secretase inhibitor to triple negative breast cancer cells and cancer stem cells [0.03%]
苯基硼酸修饰的脂质纳米载体介导免疫细胞因子TRAIL和γ-分泌酶抑制剂共传递到三阴性乳腺癌细胞及癌症干细胞中的研究
Sai Kiran S S Pindiprolu,Harani Avasarala,Sathis Kumar Dinakaran
Sai Kiran S S Pindiprolu
Triple negative breast cancer (TNBC) is an aggressive form of breast cancer with high rates of tumor relapse and metastasis. The existing drugs for treatment of TNBC are unable to target the cells of origin (breast cancer stem cells) of TNB...
Glycemia and venous thromboembolism in patients with primary brain tumors - A speculative review [0.03%]
血糖水平与原发性脑肿瘤患者的静脉血栓栓塞事件 - 一个推测性的综述
Darko Orešković,Anđelo Kaštelančić,Marina Raguž et al.
Darko Orešković et al.
Venous thromboembolism (VTE) is a significant public health issue causing severe morbidity and mortality. One of the most vulnerable populations for VTE development are cancer patients. And among them, patients with brain tumors have arguab...
Neuroinflammation as a possible link between attention-deficit/hyperactivity disorder (ADHD) and pain [0.03%]
神经炎症可能是注意缺陷多动障碍(ADHD)和疼痛之间的潜在联系
Nóra Kerekes,Ana Maria Sanchéz-Pérez,Marc Landry
Nóra Kerekes
Attention-deficit/hyperactivity disorder (ADHD) and pathological pain are two complex syndromes of multifactorial origin. Despite their prevalence and broad impacts, these conditions are seldom recognized and managed simultaneously. The co-...
Whole-body vibration combined with exercise may be more effective in lowering blood pressure and arterial stiffness than exercise alone in older adults with hypertension [0.03%]
对于高血压老年人而言，全身震动结合锻炼可能比单独锻炼更能有效降低血压和动脉僵硬度
Chidiebere Emmanuel Okechukwu
Chidiebere Emmanuel Okechukwu