Potential therapeutic effect of glucagon-like peptide-1 receptor agonists on COVID-19-induced pulmonary arterial hypertension [0.03%]
GLP-1受体激动剂对COVID-19诱发肺动脉高压的潜在治疗作用
Jong Han Lee
Jong Han Lee
Coronavirus disease 2019 (COVID-19) is an infectious diseases caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Now, it is pandemic over the world. SARS-CoV-2 often causes a "cytokine storm" in people with COVID-19, ca...
Cardiomyocytes calpain 2 expression: Diagnostic forensic marker for sudden cardiac death caused by early myocardial ischemia and an indicator of the duration of myocardial agonal period? [0.03%]
心肌细胞钙蛋白2表达：由早期心肌缺血导致的猝死的诊断法医标志物和心肌临终期长度指标？
Leon Kunišek,Koviljka Matušan Ilijaš,Igor Medved et al.
Leon Kunišek et al.
Sudden cardiac death (SCD) is an unexpected natural death of cardiac etiology and occurs within one hour of the onset of cardiac symptoms in an apparently healthy subject or within 24 h if death is not witnessed. The diagnosis of early myoc...
CCL2/ACKR2 interaction participate in breast cancer metastasis especially in patients with altered lipid metabolism [0.03%]
CCL2/ACKR2相互作用参与乳腺癌转移，特别是在脂质代谢异常的患者中
Xiaoying Zhong,Xuefei Wang,Qiang Sun
Xiaoying Zhong
Breast cancer is the most prevalent cancer worldwide and metastasis accounts for the majority of associated deaths. Altered lipid metabolism has been proved to be involved with breast cancer, yet the underlying mechanism in lipid metabolism...
Vaibhav Sahni
Vaibhav Sahni
The immune response elicited by vaccines is crucial in determining their eventual efficacy. The human microbiome, in particular, that of the gut has been demonstrated to influence the immunogenicity of vaccines delivered by both the oral an...
A mouse zoonotic virus (LCMV): A possible candidate in the causation of SIDS [0.03%]
一种鼠源性病毒（LCMV）：可能是婴儿猝死综合征的病因之一
Paul N Goldwater
Paul N Goldwater
Lymphocytic choriomeningitis virus (LCMV) is a ubiquitous virus carried by rodents. It causes human disease through contact with infectious mouse faeces, urine or secretions. The virus initially infects the human respiratory tract and lungs...
Professional responsibility between guidelines and customary practice. A conflict of interest? [0.03%]
指南与常规做法之间的专业责任．利益冲突？
Giovanni D Tebala,Zoe Slack,Vittoria Fantini et al.
Giovanni D Tebala et al.
In Countries with Common Law, the principles of medical liability in case of malpractice claim are based on the Bolam/Bolitho tests, that is, the opinion of a panel of average professionals of the same specialty. On the contrary, in Countri...
Sarah A Deek
Sarah A Deek
The emergence of coronavirus disease (COVID-19) in China at the end of 2019 has caused a large global outbreak. COVID-19 is largely seen as a thrombotic and vascular disease targeting endothelial cells (ECs) throughout the body that can pro...
Ali Al-Kaleel,Lubna Al-Gailani,Mustafa Demir et al.
Ali Al-Kaleel et al.
SARS-CoV-2 enters target cells via the ACE2 receptor and downregulates it. ACE2 exhibits high catalytic activity to produce Angiotensin 1-7 (Ang-1-7), which has a vasodilator effect and also inactivates the vasoconstrictor Angiotensin II. I...
Whole adrenal extract for Addison's disease in the 1920s: Where is the cortisol? [0.03%]
二十世纪二十年代用于艾迪生病的整体肾上腺提取物：皮质醇在哪里？
Linda L Isaacs
Linda L Isaacs
Prior to the development of synthetic corticosteroids, Addison's disease was treated with oral dessicated whole adrenal glands or crude extracts. These products could not have contained meaningful amounts of cortisol, yet some patients impr...
Are there medium to short-term multifaceted effects of the airborne pollutant PM2.5 determining the emergence of SARS-CoV-2 variants? [0.03%]
空气污染物PM2.5对SARS-CoV-2变异体的出现有中短期的多方面影响吗？
Yves Muscat Baron
Yves Muscat Baron
The COVID-19 pandemic has been characterised by successiveoutbreaks effecting large swathes of the world's populations. These waves of infection have been mainly driven by a number of more transmissiblevariants which appear to evade the pop...