Copper acetate aerosols: A possible tool complementary to vaccination in fight against SARS-CoV-2 and variants replication [0.03%]
醋酸铜气溶胶：对抗SARS-CoV-2及变异毒株复制的潜在疫苗补充工具
Roger Deloncle,Olivier Guillard,Alain Pineau et al.
Roger Deloncle et al.
In SARS-CoV-2, at the S1/S2 furin cleavage site, a four amino acid insert (P-R-R-A) not found in closely related corona viruses, has been shown to facilitate entry into respiratory epithelial cells and promote virus transmission, infectivit...
Diethylcarbamazine as potential treatment of COVID-19 lung fibrosis [0.03%]
地克珠利作为治疗COVID-19肺纤维化的潜在药物
Carlos Eduardo Medina-De la Garza,Armando Salvador Flores-Torres,Marisela García-Hernández et al.
Carlos Eduardo Medina-De la Garza et al.
Diethylcarbamazine, the antiparasitic drug, also possesses anti-inflammatory and immunomodulatory activities. The anti-fibrotic activity of diethylcarbamazine makes it a potential candidate to treat coronavirus disease 2019 (COVID-19)-relat...
Bioluminescence and ventilator-associated pneumonia caused by oral biofilm in ICU during COVID-19 -Is there a possible relationship? [0.03%]
新冠疫情下ICU患者口腔生物膜导致的生物荧光和呼吸机相关性肺炎之间可能存在关联吗？
Betsy Joseph,Liviu Steier
Betsy Joseph
Ventilator-associated pneumonia (VAP) has been claiming many lives in the intensive care unit (ICU) during COVID-19. Oral biofilm and bacterial contamination that can be passed on from the oral cavity to the lungs during endotracheal intuba...
Nanomedicine formulations for respiratory infections by inhalation delivery: Covid-19 and beyond [0.03%]
吸入给药治疗呼吸道感染的纳米药物制剂：从新冠肺炎开始
Oron Zachar
Oron Zachar
For respiratory infections treatment and prevention, we analyze for the first time the possibility of providing a broad range medication based on metallic nanoparticles colloids (NpC) delivery by controlled aerosol inhalation. (i) Based on ...
Restructuring the ONYX-015 adenovirus by using spike protein genes from SARS-CoV-2 and MERS-CoV: Possible implications in breast cancer treatment [0.03%]
利用SARS-CoV-2和MERS-CoV的刺突蛋白基因重组ONYX-015腺病毒：对乳腺癌治疗的意义
Hamendra Singh Parmar,Aakruti Nayak,Shreya Kataria et al.
Hamendra Singh Parmar et al.
Proposed mechanism for rare thrombotic events after use of some Covid-19 vaccines [0.03%]
关于某些新冠疫苗接种后罕见血栓事件的假说
Peter A Feldman
Peter A Feldman
Administration of AstraZeneca/Oxford and Johnson & Johnson/Janssen Covid-19 vaccines which use an adenovirus vector for DNA delivery has been associated with very rare thromboembolic complications coupled with an immune response to platelet...
A one-step platform for screening high-efficient and minimal off-target CRISPR/Cas13 crRNAs to eradicate SARS-CoV-2 virus for treatment of COVID-19 patients [0.03%]
用于筛选高效的CRISPR/Cas13向导RNA以消除SARS-CoV-2病毒的治疗COVID-19患者的一站式平台
Pu-Yu Li,San-Qiang Li,She-Gan Gao et al.
Pu-Yu Li et al.
Coronavirus disease 2019 (COVID-19) is a new respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and now spreads globally. Currently, therapeutics and effective treatment options remain scarce and ...
SARS-CoV-2 might transmit through the skin while the skin barrier function could be the mediator [0.03%]
新型冠状病毒可能通过皮肤传播而皮肤屏障功能可能是介导因素
Qiannan Xu,Li Zhang,Lihong Chen et al.
Qiannan Xu et al.
During the coronavirus disease 2019 (COVID-19) pandemic, it were reported that COVID-19 patients could have cutaneous symptoms, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was observed on the skin of COVID-19 patients, ...
A new hypothesis for the pathophysiology of symptomatic adult Chiari malformation Type I [0.03%]
成人I型有症状Chiari畸形发病机制的新假说
Rick Labuda,Blaise Simplice Talla Nwotchouang,Alaaddin Ibrahimy et al.
Rick Labuda et al.
Chiari malformation Type I (CMI) is characterized by herniation of the cerebellar tonsils through the foramen magnum. The pathophysiology of CMI is not well elucidated; however, the prevailing theory focuses on the underdevelopment of the p...
Valérian Dormoy,Jeanne-Marie Perotin,Philippe Gosset et al.
Valérian Dormoy et al.
Nicotinic acetylcholine receptors (nAChRs) play an important role in homeostasis and respiratory diseases. Controversies regarding the association between COVID-19 hospitalizations and smoking suggest that nAChRs may contribute to SARS-CoV-...