Are Dyskeratosis Congenita patients at higher risk of symptomatic COVID-19? [0.03%]
先天性毛细血管扩张症患者患症状性新冠肺炎的风险更高吗？
Saeed Dorgaleleh,Karim Naghipoor,Amir Hozhabrpour et al.
Saeed Dorgaleleh et al.
Dyskeratosis Congenita (DC) is a rare and heterogeneous disease. This disorder is resulted from a defect in the telomere maintenance in stem cells. Telomerase RNA component, shelterin complex, and telomerase reverse transcriptase are mutate...
Deconditioning in COVID-19 survivors with reduced exercise performance: A role for endothelial dysfunction? [0.03%]
COVID-19康复者运动表现下降与内皮功能障碍有关吗？
Pasquale Ambrosino,Mauro Maniscalco
Pasquale Ambrosino
Recent studies have reported an impaired exercise response at cardiopulmonary exercise testing (CPET) during convalescence from coronavirus disease 2019 (COVID-19). In detail, these previous reports suggest the presence of functional limita...
Marginal BH4 deficiencies, iNOS, and self-perpetuating oxidative stress in post-acute sequelae of Covid-19 [0.03%]
边缘型BH4缺乏、iNOS和自我维持的氧化应激在新冠后遗症中的作用
William A Villaume
William A Villaume
The treatment of post-acute sequelae of Covid-19 (PASC) has been informed primarily by symptomatic parallels with other chronic inflammatory syndromes. This manuscript takes a more systemic approach by examining how a marginal deficiency of...
Calcitonin gene-related peptide: A biomarker for stroke in SARS-CoV-2 infection? [0.03%]
降钙素基因相关肽：SARS-CoV-2感染所致卒中的生物标志物？
Yassamine Ouerdane,Yahia Khlidj,Mohamed S Attia et al.
Yassamine Ouerdane et al.
COVID-19 infection was mainly associated with respiratory symptoms, but lately, ischemic stroke (IS) has been reported in several cases. The incidence of IS in SARS-CoV-2 infection is increasing, and its mechanism is still not fully underst...
Jordi González-Menacho,Mónica Villas-Roca,Helena Castañé et al.
Jordi González-Menacho et al.
Chronic headache is a frequent disorder that can cause a significant deterioration in the quality of life of the affected person. The COVID-19 pandemic is compelling all countries to develop a complete vaccination protocol for the entire po...
Combatting future variants of SARS-CoV-2 using an in-silico peptide vaccine approach by targeting the spike protein [0.03%]
通过针对刺突蛋白的计算肽疫苗方法应对未来的萨斯 cov-2 变异毒株
Subhamoy Biswas,Sumanta Dey,Shreyans Chatterjee et al.
Subhamoy Biswas et al.
The far-reaching effects of the SARS-CoV-2 pandemic have crippled the progress of the world today. With the introduction of newer and newer mutated variants of the virus, it has become necessary to have a vaccine that remains useful against...
Will the bone mineral density in postmenopausal women get worse during the COVID-19 pandemic? [0.03%]
围绝经期女性的骨密度会在新冠肺炎疫情期间下降吗？
Yunzhong Cheng,Honghao Yang,Ziyang Liu et al.
Yunzhong Cheng et al.
l-Methionine may modulate the assembly of SARS-CoV-2 by interfering with the mechanism of RNA polymerase [0.03%]
L-蛋氨酸可能通过干扰RNA聚合酶的机制来调节SARS-CoV-2的装配过程
Maximo A Benavides
Maximo A Benavides
Coronaviruses have received worldwide attention following several severe acute respiratory syndrome (SARS) epidemics. In 2019, the first case of coronavirus disease (COVID-19) caused by a novel coronavirus (SARS-coronavirus 2 [CoV-2]) was r...
Post-adenoviral-based vaccines Guillain-Barre Syndrome: A proposed mechanism [0.03%]
基于腺病毒的疫苗引起的吉兰-巴雷综合征：一个假说机制
Kamran Kadkhoda
Kamran Kadkhoda
Despite great public health advances achieved by COVID-19 vaccines, rare side effects may impact the public acceptance. Guillain-Barre Syndrome has increasingly been reported with adenoviral-based vaccines. This perspective proposes a possi...
Mitochondrial hijacking: A potential mechanism for SARS-CoV-2 to impair female fertility [0.03%]
线粒体劫持：SARS-CoV-2 可能通过该机制损害女性生育力的一种机制
Jun Sun,Qiong Liu,Xinling Zhang et al.
Jun Sun et al.
As well as causing respiratory lesions, the multi-organ complications caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are also well known. Combined with the epidemiological characteristics of SARS-CoV-2 with high tran...