Healthcare resource utilization and persistence in children and adults with Dravet syndrome receiving fenfluramine: a retrospective analysis using United States claims data [0.03%]
一项使用美国索赔数据的回顾性分析：芬氟拉明治疗儿童和成人德拉韦综合征患者的医疗资源利用与依从性
Wesley T Kerr,Derek Ems,Srihari Jaganathan et al.
Wesley T Kerr et al.
Purpose: Dravet syndrome (DS) is a rare and lifelong developmental and epileptic encephalopathy marked by high seizure burden and developmental, motor, and behavioral impairments. Using US claims data, treatment persisten...
Early Electroencephalographic Changes After Ketogenic Diet Initiation Are Associated With Clinical Response in Pediatric Drug-Resistant Epilepsy [0.03%]
生酮饮食治疗难治性癫痫早期脑电改变与临床疗效相关性研究
Merve Yavuz,Aycan Unalp,Feyza Gulagız et al.
Merve Yavuz et al.
Background: Ketogenic diet (KD) is an established treatment option for pediatric drug-resistant epilepsy; however, early indicators of treatment response are limited. This study aimed to explore whether early changes in r...
Delirium in critically ill patients treated with levetiracetam or brivaracetam: a comparative study [0.03%]
利凡斯的明和布瓦斯的明治疗重症患者谵妄的比较研究
Manuel Alanís-Bernal,Anna Sánchez,Laura Doménech-Moral et al.
Manuel Alanís-Bernal et al.
Introduction: Delirium is a common complication in the Intensive Care Unit (ICU) with relevant clinical impact. Levetiracetam (LEV) and brivaracetam (BRV) are widely used antiseizure medications. LEV has been linked to be...
Clinical and EEG features integrated by a deep learning method to investigate treatment outcomes in epilepsy with eyelid myoclonia [0.03%]
结合临床和EEG特征的深度学习方法在眼睑肌阵挛性癫痫治疗效果中的应用研究
Yue Niu,Ang Ma,Pan Gong et al.
Yue Niu et al.
Objective: To explore the correlation between clinical and electroencephalogram (EEG) factors and therapeutic outcome in epilepsy with eyelid myoclonia (EEM). ...
P Boon,B Schmitz,P House et al.
P Boon et al.
Introduction: Epilepsy is a prevalent brain condition, affecting 50 million people worldwide. Achieving seizure freedom (SF) without intolerable adverse events should be the primary treatment goal. However, the lack of st...
What is the impact of stigma on the wellbeing of children with epilepsy?: A qualitative systematic literature review [0.03%]
污名对癫痫儿童健康的影响：定性系统文献综述
Rebekah Coates,Mark Hudson,Thomas Schröder et al.
Rebekah Coates et al.
Epilepsy has long been a misunderstood condition that is subject to stigmatised views by society. This systematic review aimed to identify the impact of stigma upon the social, emotional and physical wellbeing of children with epilepsy. Fou...
Genetic analysis of self-limiting familial infantile epilepsy caused by PRRT2 variants in Indian patients [0.03%]
PRRT2基因变异导致的印度患者婴幼儿自限性家族性癫痫的遗传学分析
Revathi Sampath,Prabhakara Somanna,Vykuntaraju K Gowda et al.
Revathi Sampath et al.
Introduction: Self-limiting familial infantile epilepsy (SeLFIE) is an epilepsy syndrome characterized by recurrent focal motor seizures. It follows an autosomal dominant inheritance pattern. Phenotypic and genetic hetero...
Does genetic diagnosis influence long-term seizure and developmental outcomes in childhood developmental and epileptic encephalopathies? A longitudinal audit [0.03%]
遗传诊断对儿童发育性和癫痫性脑病长期发作和发育结局的影响？一项纵向审计研究
Prasannakumar Surabhi,Alfiya Fasaludeen,Manna Jose et al.
Prasannakumar Surabhi et al.
Objective: To evaluate long-term seizure and developmental outcomes of childhood-onset developmental and epileptic encephalopathies (DEE) of presumed genetic etiology and to determine whether genetic diagnosis influences ...
Prenatal exposure to Antiseizure Medications for all indications and the risk of neurodevelopmental disorders in offspring: a nationwide population-based cohort study in South Korea [0.03%]
孕妇暴露于所有适应症的抗癫痫药物与后代神经发育障碍风险的相关性：一项基于韩国全国人群的队列研究
Hyunjoo Kim,Seulbi Lee,Nayeong Son et al.
Hyunjoo Kim et al.
Purpose: Antiseizure medications (ASMs) are used during pregnancy for both epilepsy and non-epilepsy indications, yet the neurodevelopmental safety of prenatal ASM exposure remains uncertain, particularly in Asian populat...
Adjunctive transcranial DC stimulation in the management of refractory drug-resistant focal epilepsy in POLG mitochondrial disease: A case series [0.03%]
经颅直流电刺激联合治疗POLG线粒体疾病难治性药物抵抗性局灶性癫痫的病例系列研究
Katrin A Bangel,Yi Ng,Albert Lim et al.
Katrin A Bangel et al.
Background: Pathogenic POLG variants produce an age-related progressive multi-system mitochondrial disorder, with neurologic manifestations that include focal onset seizures, stroke-like episodes, cerebellar ataxia, senso...