High-throughput clone screening and upstream process optimization for recombinant therapeutic peptide expression: biosimilar teriparatide (PTH-34): a case study [0.03%]
重组治疗性肽表达的高通量克隆筛选及上游工艺优化：特利帕肽(PHT-34)类似药案例研究
Santosh Ughade,Mrunali Nandanwar,Gauri Yoge et al.
Santosh Ughade et al.
The study focuses on high-throughput optimization of the upstream process for the expression of biosimilar teriparatide using a microfermenter platform. Key upstream parameters, including E. coli host strains, growth media, and induction st...
Bioprocessing of rice starch: advances in extraction, modification, and analytical characterization [0.03%]
稻米淀粉生物加工：提取、修饰及分析表征的新进展
Ganesh Bansi Patil,Maheshkumar Prakash Patil,Pragati Bhatu Patil et al.
Ganesh Bansi Patil et al.
Rice starch is an important biodegradable biopolymer widely utilized in food, pharmaceutical, and industrial sectors, where its performance depends strongly on its structural and functional properties. This review provides a comprehensive e...
Optimization of extraction, structural modification, and bioactivity of polysaccharides from Euphorbia trigona Mill. and their derivatives [0.03%]
Euphorbia trigona Mill. 多糖的提取优化、结构修饰及生物活性研究
Xiaoliang Zhao,Yuanyuan Ma,Haidong Wen et al.
Xiaoliang Zhao et al.
The optimal hot water extraction process for a polysaccharide from Euphorbia trigona Mill. was established using single-factor and orthogonal experiments, yielding the best conditions of a 1:30 (g/mL) solid-to-liquid ratio at 90 °C for 3.5...
Improving thermostability of Acinetobacter baumannii phages during cold storage through infecting naïve bacterial hosts [0.03%]
通过感染未受感染的细菌宿主提高阿氏伯克霍尔德菌噬菌剂在冷藏过程中的热稳定性
Yi-Hsuan Huang,Chung-Hsin Wu,San-Ho Hung et al.
Yi-Hsuan Huang et al.
Despite prior research on optimal temperatures for Acinetobacter baumannii phage storage, thermostability of phages produced from original versus naïve hosts was not addressed. Three A. baumannii phages harvested from three multidrug-resis...
Co-immobilization of β-galactosidase and neutrase® on biopolymer supports for integrated whey valorization [0.03%]
固定在生物聚合物支持物上的β-半乳糖苷酶和中性蛋白酶的共包封集成技术用于乳清资源化回收
Elisangela Batista da Silva,Alanna Shirley Morais de Faria,Larissa Leite da Silva et al.
Elisangela Batista da Silva et al.
The co-valorization of lactose and proteins from dairy by-products offers both environmental and technological opportunities. In this study, bifunctional biocatalysts were developed by co-immobilizing β-galactosidase and Neutrase® onto gl...
Rosa Slamani,Redouane Labadi,Djamila Yatta et al.
Rosa Slamani et al.
Despite their significant potential for recovery, animal by-products such as offal are often considered waste in the meat industry. Our study focused on extracting pepsin from sheep abomasa and analyzing its catalytic activity in milk from ...
Zeolite‑integrated airlift membrane bioreactor for citrus processing wastewater: enhanced COD removal and fouling mitigation [0.03%]
集成了分子筛的空气_lift_膜生物反应器处理柑橘加工废水：增强的cod去除和污染缓解
Farshid Pajoum Shariati,Geoffroy Lesage,Salar Helchi et al.
Farshid Pajoum Shariati et al.
Citrus-processing wastewater (CPWW) is challenging to treat due to low pH, high organic load, and inhibitory effects of d-limonene, which suppress biological activity and exacerbate membrane fouling. Conventional membrane bioreactors (MBRs)...
Production of Rhizopus oryzae by solid state fermentation and evaluation of its biocomposite characteristics [0.03%]
固态发酵生产Rhizopus或yzae及其生物复合材料性能评估
Sevim Özgül,Ahmet Düzel,Günnur Koçar et al.
Sevim Özgül et al.
Rhizophus oryzae biomass (RB) can be incorporated into polylactic acid (PLA) to create improved biocomposites that perfectly fit the biobased circular economy model. In this study, Rhizopus oryzae EGE-F75, produced through solid-state ferme...
Isolation, optimization, and bioactivity evaluation of Streptomyces qinglanensis VITABS23 from mangrove sediments: an in vitro and in silico study [0.03%]
从红树林沉积物中分离出来的链霉菌青蓝菌素素VITABS23的隔离、优化及生物活性评价：体外和计算机模拟研究
Apsara S Babu,K V Bhaskara Rao
Apsara S Babu
Mangroves are valuable ecosystems that harbor unique actinobacteria capable of producing bioactive compounds of therapeutic importance. In the present study, a total of 26 marine actinobacteria were isolated using actinomycetes isolation ag...
Extreme Glycosyl Hydrolases: strategic biological agents for the circular economy [0.03%]
极端糖基水解酶：生物经济中的战略生物制剂
Bárbara Ruivo Válio Barretti,Esteffany Helscher Candeo,Alessandra Cristine Novak Sydney et al.
Bárbara Ruivo Válio Barretti et al.
Glycosyl hydrolases (GH) are enzymes that catalyze the hydrolysis of glycosidic bonds in complex polysaccharides, such as cellulose and starch, and are among the most important biocatalysts applied in biorefinery processes. Significant amou...