Human growth hormone measurement by means of a sensitive ELISA of whole blood spots on filter paper [0.03%]
敏感滤纸全血点样ELISA法测定生长激素
M Langkamp,K Weber,M B Ranke
M Langkamp
Background: Measurements of human growth hormone (hGH) are a prerequisite for identifying a deficiency or excess. Our study is the first to investigate the reliability of a very sensitive assay for the quantification of G...
Evaluation of cognitive performance by using P300 auditory event related potentials (ERPs) in patients with growth hormone (GH) deficiency and acromegaly [0.03%]
生长激素缺乏和肢端肥大患者利用P300听觉事件相关电位评估认知功能
F Tanriverdi,H Yapislar,Z Karaca et al.
F Tanriverdi et al.
Context: Impaired cognitive performance has been demonstrated in adults with GH deficiency and acromegaly by using different neuropsychological tests. P300 event related potential (ERP) application is a well established n...
IGF-I improved bone mineral density and body composition of weaver mutant mice [0.03%]
IGF-I改善Weaver突变小鼠的骨矿物质密度和身体组成
Weiguo Yao,Jin Zhong,Jun Yu et al.
Weiguo Yao et al.
Our recent report on a parallel decrease in the body weights and serum IGF-I levels of weaver mice suggests that IGF-I's endocrine function may be impaired in neurodegenerative diseases. To further understand the overall effects of IGF-I de...
Multidimensional reference regions for IGF-I, IGFBP-2 and IGFBP-3 concentrations in serum of healthy adults [0.03%]
健康成人血清胰岛素样生长因子I、结合蛋白2和结合蛋白3浓度的多维参考区间
Anders Mattsson,Dag Svensson,Burkhardt Schuett et al.
Anders Mattsson et al.
Context: The insulin-like growth factor (IGF) system exerts many effects on the growth and differentiation of both normal and malignant cells. The serum concentrations of insulin-like growth factor I (S-IGF-I), insulin-li...
IGF-I and not IGF-II expression is regulated by glucocorticoids in human fetal epiphyseal chondrocytes [0.03%]
糖皮质激素调节人胎儿骨骺软骨细胞中胰岛素样生长因子I而不是胰岛素样生长因子II的表达
M Fernandez-Cancio,C Esteban,A Carrascosa et al.
M Fernandez-Cancio et al.
Objective: To elucidate the involvement of IGF axis components and the potential effects of glucocorticoids (GCs) in human fetal growth regulation. Design...
Recombinant human insulin-like growth factor-binding protein 3 inhibits tumor growth and targets the Akt pathway in lung and colon cancer models [0.03%]
重组人胰岛素样生长因子结合蛋白3通过抑制肿瘤生长并靶向Akt途径来对抗肺癌和结肠癌模型中的癌症
Nezha Alami,Viviane Page,Qingnan Yu et al.
Nezha Alami et al.
Objective: Insulin-like growth factor-binding protein 3 (IGFBP-3) can induce antiproliferative and proapoptotic effects in human cancer cells, by IGF-I independent mechanisms. The antitumor efficacy of recombinant human I...
Effects of growth hormone overexpression vs. growth hormone receptor gene disruption on mouse hindlimb muscle fiber type composition [0.03%]
生长激素过度表达和生长激素受体基因缺失对小鼠后肢肌纤维类型组成的影响
Mark D Schuenke,John J Kopchick,Robert S Hikida et al.
Mark D Schuenke et al.
Objective: The present study characterizes the fiber type composition of selected hindlimb muscles from two transgenic mouse lines specifically engineered to alter the amounts of circulating growth hormone (GH) and insuli...
Changes in lipoprotein (a) levels measured by six kit methods during growth hormone treatment of growth hormone deficient adults [0.03%]
六种试剂盒方法测量生长激素缺乏成人治疗过程中脂蛋白(a)水平的变化
G Wieringa,SM Shalet
G Wieringa