Growth hormone receptor immunoreactivity is increased in the subventricular zone of juvenile rat brain after focal ischemia: a potential role for growth hormone in injury-induced neurogenesis [0.03%]
青春期大鼠局灶性脑缺血后侧脑室下区生长激素受体免疫反应性的增加：生长激素在损伤诱导的神经发生中的潜在作用
Larissa Joy Christophidis,Thorsten Gorba,Malin Gustavsson et al.
Larissa Joy Christophidis et al.
Background: During recovery from an ischemic brain injury, a cerebral growth hormone (GH) axis is activated. Whilst GH has been demonstrated to be neuroprotective both in vitro and in vivo, a role for GH in neuro-restorat...
E Eryl Bassett,Ioulietta Erotokritou-Mulligan
E Eryl Bassett
The detection of growth hormone (GH) abuse by athletes raises statistical problems as well as biochemical ones. We outline the statistical approaches to the various issues which have arisen during the work of the GH-2000 and GH-2004 teams; ...
W Matthew Widdowson,Marie-Louise Healy,Peter H Sönksen et al.
W Matthew Widdowson et al.
The growth hormone (GH)/ insulin-like growth factor-I (IGF-I) axis exerts short-and long-term metabolic effects that are potentially important during exercise. Exercise is a potent stimulus to GH release and there is some evidence that the ...
Perspective: proteomic approach to detect biomarkers of human growth hormone [0.03%]
透视：蛋白质组方法发现生长激素生物标志物
Juan Ding,Edward O List,Shigeru Okada et al.
Juan Ding et al.
Several serum biomarkers for recombinant human growth hormone (rhGH) have been established, however, none alone or in combination have generate a specific, sensitive, and reproducible 'kit' for the detection of rhGH abuse. Thus, the search ...
Stephen D R Harridge,Cristiana P Velloso
Stephen D R Harridge
Gene doping is the term given to the potential misuse of gene therapy for the purposes of enhancing athletic performance. Insulin like growth factor-I (IGF-I), the prime target of growth hormone action, is one candidate gene for improving p...
Growth hormone and the adolescent athlete: What are the data for its safety and efficacy as an ergogenic agent? [0.03%]
生长激素与青少年运动员：其作为运动促进剂的安全性和有效性的数据是什么？
Alan D Rogol
Alan D Rogol
There is great interest among athletes and in the sports and general media for the subject of "doping" with human growth hormone (hGH). The hype about this substance goes far beyond the available data. The issue of administration of recombi...
Minoru Irie,Makoto Ueki,Yoshifumi Kishikawa et al.
Minoru Irie et al.
Following the successful production of recombinant 20K-GH, several studies investigating the physiology of this GH isoform have been undertaken. In this report, we review studies of its biological effect, measurement and secretion. To use s...
M R Stow,N Wojek,J Marshall
M R Stow
Background and objectives: Human growth hormone (hGH) is seen as a doping risk in sport because of its possible anabolic and lipolytic effects. As a result of this hGH is prohibited for athletes to use both in and out-of-...