Discontinuation of hormone replacement therapy in young GH-treated hypopituitary women increases liver enzymes [0.03%]
年轻GH治疗垂体功能减退女性的激素替代疗法中断可增加肝酶水平
Christian Høst,Jens J Christiansen,Jens S Christiansen et al.
Christian Høst et al.
Objective: Hypopituitarism, often characterized by hypogonadism, is associated with central obesity, increased cardiovascular and endocrine morbidity and mortality. In Turner syndrome, which is also characterized by hypog...
Transforming growth factor-beta1 modulates insulin-like growth factor binding protein-4 expression and proteolysis in cultured periosteal explants [0.03%]
转化生长因子-β1调节培养的骨外膜移植中胰岛素样生长因子结合蛋白-4的表达及降解
Carlos Gonzalez,Kiem G Auw Yang,Joseph H Schwab et al.
Carlos Gonzalez et al.
Objective: Periosteum is involved in bone growth and fracture healing and has been used as a cell source and tissue graft for tissue engineering and orthopedic reconstruction including joint resurfacing. Periosteum can be...
Involvement of sensory nerves in the protective effect of growth hormone on acute pancreatitis [0.03%]
感觉神经在生长激素对急性胰腺炎保护作用中的参与研究
Jolanta Jaworek,Anna Leja-Szpak,Artur Dembiński et al.
Jolanta Jaworek et al.
Growth hormone (GH) has been shown to protect the intestinal barrier integrity and to stimulate the production of insulin-like growth factor 1 (IGF-1), which inhibits the development of acute pancreatitis. Sensory nerves are implicated in t...
Overview of the legal framework applicable to the marker method for the detection of human growth hormone [0.03%]
人绒毛膜促性腺激素检测标记法的法律框架概述
Richard R Young,Jennifer S Bielak,Sarah L Horvitz
Richard R Young
The world of doping and anti-doping in sport is an ongoing race between those who want to gain a performance advantage by using prohibited substances or methods and those who want to keep the sport clean. Sophisticated doping often involves...
David A Cowan,Christiaan Bartlett
David A Cowan
Two important biomarkers for the identification of growth hormone or IGF-I administration are IGF-I and P-III-P. These substances are determined in plasma or preferably in serum. There are a number of assays on the market for IGF-I but only...
Evaluation of IGF-2/ApaI polymorphism in pregnant women infected with human immunodeficiency virus type 1 taking antiretroviral drugs [0.03%]
评估抗逆转录病毒药物治疗的人类免疫缺陷病毒感染孕妇中IGF-2/APaI多态性的影响
Alessandra C Marcolin,Geraldo Duarte,Silvana M Quintana et al.
Alessandra C Marcolin et al.
Objective: Studies carried out to assess the effects of antiretroviral drugs (ARV) in HIV-1 infected pregnant women have demonstrated carbohydrate intolerance. Some reports also refer to the effect of disturbances in the ...
IGFBP-1 protease activity and IGFBP-1 fragments in a patient with multiple myeloma [0.03%]
一名多发性骨髓瘤患者体内的胰岛素样生长因子结合蛋白-1酶切活性及其片段的研究
Katrin Brandt,Jing Wang,Kerstin Lundell et al.
Katrin Brandt et al.
Objective: Cleavage of IGFBPs by proteases results in IGFBP fragments that have altered IGF-binding affinity, and IGF-independent roles. We have previously purified a specific IGFBP-1 protease activity from the urine of a...
Potential benefits of recombinant human growth hormone (rhGH) to athletes [0.03%]
重组人生长激素(rhGH)对运动员的潜在益处
Michael R Graham,Julien S Baker,Peter Evans et al.
Michael R Graham et al.
Athletes have enjoyed almost a thirty year amnesty of rhGH abuse, which they consider has contributed to the winning of medals and the breaking of world records. Such a reprieve is almost at an end, since WADA have identified a method to de...
Matthew Pinsent
Matthew Pinsent
Peter H Sönksen,Richard I G Holt
Peter H Sönksen