Evaluation of neuroendocrine deficits following traumatic brain injury: The role of a neurorehabilitation specialist [0.03%]
创伤性脑损伤后神经内分泌缺陷的评估：神经康复专家的作用
Chantel T Debert,Kirstie Lithgow
Chantel T Debert
Traumatic brain injury (TBI) is a common injury that can lead to significant and prolonged morbidity. Growing evidence suggests hypopituitarism is prevalent after TBI and if left untreated, contributes to high symptom burden, limited rehabi...
Alexandra Guevara,John Kopchick
Alexandra Guevara
Cancer remains as the most feared human disease and embodies deep psychological and physical suffering (1). It is one of the unsolved medical problems nowadays and constitutes a heavy burden not only for the individual and his family but al...
Alexandra Guevara,George Bright
Alexandra Guevara
Under normal circumstances, the GH/IGF-I axis is the main hormonal influence for longitudinal growth and adult height in males and females. Opposite to that, epiphyseal fusion, skeletal characteristics and fat distribution are mediated by e...
Vivian Gallardo,Enrique Teran,Fernando Cassorla
Vivian Gallardo
Children born small for gestational age (SGA) represent a heterogeneous population with an increased risk of persistent short stature and adverse metabolic outcomes later in life. Although most SGA infants exhibit spontaneous catch-up growt...
Low IGF-1 combined with a single clonidine stimulation test as a confirmatory tool for pediatric growth hormone deficiency [0.03%]
低IGF-1联合单次克罗宁刺激试验作为儿童生长激素缺乏症的确诊工具
Khomsak Srilanchakon
Khomsak Srilanchakon
Background: Growth hormone deficiency (GHD) in children is a complex endocrine disorder that requires dynamic testing for accurate diagnosis due to the pulsatile nature of growth hormone (GH) secretion. The clonidine test...
Altered gut microbiome and post traumatic hypopituitarism in chronic TBI: The need for recognition, evaluation and treatment [0.03%]
慢性创伤性脑损伤患者的肠道微生态改变和垂体功能减退：需要正确认识、评估及治疗
Sefanie Howell,Giuliana Cumpa,Brent E Masel
Sefanie Howell
Post traumatic hypopituitarism (PTHP) occurs in 30-50% of individuals with chronic moderate-severe TBI as well as individuals with mild TBIs who remain symptomatic after a year. Growth hormone deficiency (GHD) occurs in approximately 15-20%...
Circulating IGF-1 levels and 27 digestive diseases: 461,401 UK biobank prospective analysis [0.03%]
循环IGF-1水平与27种消化系统疾病：来自英国生物样本库的前瞻性分析
Wenwen Yang,Jie Gao,Zhixian Bao et al.
Wenwen Yang et al.
Insulin-like growth factor-1 (IGF-1) regulates gastrointestinal mucosal repair, hepatocyte function, and metabolic homeostasis, but its association with a broad spectrum of digestive diseases remains unsystematic. We analyzed 461,401 UK Bio...
IGF-1 as a mediator in the association between body mass index and risk of liver cancer: A prospective analysis of 432,203 participants from the UK biobank [0.03%]
生长因子IGF-1在BMI与肝癌风险的关联中起到介导作用：英国生物样本库队列中432203例参与者前瞻性分析
Wenwen Yang,Zhixian Bao,Yuhua Chen et al.
Wenwen Yang et al.
Purpose: This study aimed to quantify the extent to which IGF-1 mediates the association between BMI and liver cancer risk, clarifying its role in adiposity-related liver carcinogenesis. ...
Prevalence and clinical correlates of pre-operative glucose homeostasis in patients with acromegaly [0.03%]
阿克罗梅格患者术前糖代谢异常的患病率及其临床特征分析
Po-Wei Chiang,Harn-Shen Chen
Po-Wei Chiang
Context: Comprehensive assessments of the prevalence of prediabetes and glucose intolerance are scarce for acromegaly. Objective: To es...
Pituitary hormone abnormalities following military-related traumatic brain injuries [0.03%]
与创伤性脑损伤相关的垂体激素异常现象
Megan Herodes,Jose M Garcia
Megan Herodes
Pituitary hormone abnormalities are not uncommon among individuals who have sustained a traumatic brain injury (TBI), particularly among the military population which has a higher prevalence of lifetime TBI due to the risks associated with ...