Calcitonin Gene-Related Peptide (CGRP) Levels of Children and Adolescents With Migraine: A Systematic Review and Meta-Analysis of Observational Studies [0.03%]
儿童和青少年偏头痛患者降钙素基因相关肽(CGRP)水平的系统评价和 meta 分析
Guoliang Zhu,Guifang Yan,Ying Luo et al.
Guoliang Zhu et al.
Background and objective: Although calcitonin gene-related peptide (CGRP) has emerged as a promising therapeutic target in migraine management, current clinical evidence regarding its dynamic variations in paediatric migr...
Longitudinal Outcome Evaluations of Interdisciplinary Multimodal Pain Treatment Programs for Patients With Chronic Primary Musculoskeletal Pain: A Living Systematic Review [0.03%]
多学科慢性原发性肌骨痛综合治疗项目的纵向结局评估：系统综述
Elise Cnockaert,Kirsty Musch,Stefan Elbers et al.
Elise Cnockaert et al.
Background and objectives: Interdisciplinary Multimodal Pain Treatment (IMPT), grounded in the biopsychosocial model, is strongly recommended for patients with chronic primary pain. A base review found that IMPT participa...
Winfried Häuser,Eva Kosek
Winfried Häuser
Background: Nociplastic pain, a third mechanistic pain descriptor in addition to nociceptive and neuropathic pain is defined as 'pain that arises from altered nociception' not fully explained by nociceptive or neuropathic...
Differential Operant Conditioning of Emotional-Motivational and Sensory-Discriminative Pain Responses [0.03%]
操作性条件作用在情绪动机性和感觉辨别性疼痛反应中的差异作用
Melissa L Flury,Martin Löffler,Shaili Gour et al.
Melissa L Flury et al.
Background: The experience of pain consists of different components, including sensory-discriminative and emotional-motivational components. While these components are often well aligned, they can also dissociate. Operant...
Exploratory Pain Profiling With Quantitative Sensory Testing (QST) in Episodic and Chronic Migraine [0.03%]
定量感觉检测在发作性 migraine和慢性migraine中的探索性疼痛特征分析
Rein F van Welie,Floor C van Welie,Jennifer P Trouerbach-Kraan et al.
Rein F van Welie et al.
Background: Migraine pain profiling studies vary by sensory modalities, methods, anatomical sites and characteristics. This exploratory study aimed to identify pain profiling parameters using quantitative sensory testing ...
Graded Motor Imagery (GRAMI Protocol) for Phantom Limb Pain: A Randomised Clinical Trial of Home-Based Intervention [0.03%]
分级运动想象（GRAMI方案）治疗幻肢痛：居家干预的随机临床试验
Sandra Rierola-Fochs,Marc Terradas-Monllor,Sergi Grau-Carrión et al.
Sandra Rierola-Fochs et al.
Background: Phantom limb pain (PLP) affects 64% of individuals who have undergone amputation. Various theories explain its development, leading to different treatments, including graded motor imagery. This study analyses ...
Randomized Controlled Trial
European journal of pain (London, England). 2026 Jan;30(1):e70167. DOI:10.1002/ejp.70167 2026
Locus Coeruleus MR Measured Signal Intensity in Fibromyalgia Relative to Healthy Controls [0.03%]
多发性肌痛患者蓝斑核磁信号强度较正常对照的研究
Marilena M DeMayo,Clifford M Cassidy,Cheryl McCreary et al.
Marilena M DeMayo et al.
Background: Fibromyalgia is a chronic pain condition without an established aetiology. However, noradrenergic dysfunction is a possible mechanism to explain the constellation of symptoms associated with fibromyalgia. Nora...
Optimising Treatment Expectations Using a Video-Based Intervention in Orthopaedic Surgery: Results From a Randomised Controlled Trial [0.03%]
一种基于视频的干预措施在骨科手术中优化治疗预期的结果：一项随机对照试验的结果
Simon F Zerth,Christian Volberg,Ann-Kristin Schubert et al.
Simon F Zerth et al.
Background: Psychological interventions designed to optimise patients' treatment expectations have proven effective in surgical populations. Since these interventions are often resource-intensive, their clinical applicati...
Randomized Controlled Trial
European journal of pain (London, England). 2025 Nov;29(10):e70169. DOI:10.1002/ejp.70169 2025
Change in Healthcare Use After a Self-Management Supportive Intervention for Low Back Pain-A Quasi-Experimental Study [0.03%]
一项针对下腰痛的自我管理支持性干预措施对医疗服务使用变化的影响——准实验研究
Søren Grøn,Melker Johansson,Kim Rose Olsen et al.
Søren Grøn et al.
Background: Individuals with low back pain (LBP) have high healthcare use (HCU). It is currently unclear whether self-management supportive interventions can decrease HCU among patients with LBP. The aim of this study was...
Evaluating Manual Therapy in Musculoskeletal Pain: Why Certain Trial Designs May Overestimate Effectiveness-A Scoping Review [0.03%]
评价骨科疼痛手动治疗功效：为何某些试验设计可能高估疗效-综述性研究
Jean-Pascal Grenier,Alex Thiel
Jean-Pascal Grenier
Background and objective: Atraumatic musculoskeletal pain, regardless of the affected body region, is a highly prevalent condition impacting over 25% of the global population and contributing significantly to the burden o...