Family History of Chronic Pain: What Impact Does It Have on Current Clinical Status? Results From an Italian Study [0.03%]
慢性疼痛的家族史对当前临床状态有何影响？一项意大利研究的结果
Simona Pupo,Camilla Barbi,Marika Alessia Incardona et al.
Simona Pupo et al.
Background: Although a key factor in understanding intergenerational transmission, family history of chronic pain deserves greater attention, particularly about its role as a potential mediating factor on current psychoph...
Rainer Freynhagen,Bart Morlion,Antonio Alcántara Montero et al.
Rainer Freynhagen et al.
Background: For decades, clinicians and researchers have struggled to classify pain conditions that do not fit neatly into the nociceptive, neuropathic or nociplastic frameworks. Many common disorders-from chronic low bac...
Catheter-Based Sacral Nerve Block Versus Pudendal Nerve Block in the Treatment of Pudendal Neuralgia: A Randomized Double-Blinded Controlled Trial [0.03%]
骶神经导管阻滞与会阴神经阻滞治疗会阴神经痛的随机双盲对照试验
Kai-Kai Guo,Jing Li,Ying Meng et al.
Kai-Kai Guo et al.
Background: Pudendal neuralgia (PN) severely impacts quality of life, particularly sitting. Uncertainty exists whether catheter-based sacral nerve block with daily intermittent bolus (SNB) or pudendal nerve block (PNB) is...
Randomized Controlled Trial
European journal of pain (London, England). 2026 Aug;30(7):e70355. DOI:10.1002/ejp.70355 2026
Social Relationships and Experimental Pain Sensitivity in Healthy Adolescent Girls: An Exploratory Preliminary Study [0.03%]
健康少女中的社会关系和实验痛阈值：一项初步探索性研究
Elizabeth Mulat,Gourav Banerjee,Rachel Cundiff-O&#x;Sullivan et al.
Elizabeth Mulat et al.
Introduction: Greater understanding of relationships between social factors and pain responses can provide new modifiable targets for pain interventions in adolescents. This observational preliminary exploratory study aim...
Observational Study
European journal of pain (London, England). 2026 Aug;30(7):e70353. DOI:10.1002/ejp.70353 2026
Five-Year Trajectories of Disability in Older Adults Seeking Care for Back Pain in the Netherlands: BACE-Dutch Cohort [0.03%]
荷兰背痛患者老年群体的五年残疾发展轨迹：BACE 荷兰队列研究
Yanyan Fu,Trynke Hoekstra,Bart Koes et al.
Yanyan Fu et al.
Background: Investigating trajectories in older people with back pain (BP) is informative for estimating prognosis and initiating personalized treatment. We aimed to identify 5-year trajectories of BP-related disability i...
Lesion Without Pain, Pain Without Certainty: A Critical Reappraisal of the NeuPSIG Diagnostic Algorithm for Neuropathic Pain [0.03%]
无痛性病变，无 certainty 痛：对 NeuPSIG 神经病理性疼痛诊断算法的批判性再评价
Didier Bouhassira,Nadine Attal
Didier Bouhassira
Background: The NeuPSIG diagnostic algorithm is regarded as the reference framework for the diagnosis of neuropathic pain. It is based on a hierarchical model in which diagnostic certainty increases with the presumed obje...
SARS-CoV-2 Spike Peptides Trigger Nociceptive Responses Through Spinal TLR4 Pathways [0.03%]
新冠病毒刺突肽通过脊髓 Toll 样受体 4 通路触发伤害性反应
Bruno Eduardo Silva,Rayner Ribeiro Cardoso,Lívia Maria Ribeiro Rosário et al.
Bruno Eduardo Silva et al.
Background: Pain is a common neurological manifestation of COVID-19, yet the mechanisms by which SARS-CoV-2 spike protein fragments contribute to nociceptive processing remain poorly understood. We investigated whether sp...
Trends and Characteristics of Opioid Use During Pregnancy Between 2010 and 2023: A French Nationwide Drug Utilization Study [0.03%]
2010至2023年法国全国范围内孕期阿片类药物使用趋势和特征研究
Laurent Chouchana,Philippe Herlemont,Hugo Jourdain et al.
Laurent Chouchana et al.
Background: While opioid use during pregnancy has raised concerns worldwide, population-based data in Europe remain limited. In France, little is known about opioid use in the context of pregnancy. ...
Do Acceptance- and Mindfulness-Based Interventions Improve Psychological Flexibility in People With Chronic Pain? A Systematic Review and Meta-Analysis of Randomized Controlled Trials [0.03%]
基于接纳和正念的干预措施可提高慢性疼痛患者的心理灵活性吗？一项随机对照试验的系统评价和荟萃分析
Juan P Sanabria-Mazo,Carla Rodríguez-Freire,Estíbaliz Royuela-Colomer et al.
Juan P Sanabria-Mazo et al.
Background: Acceptance- and mindfulness-based interventions are effective for improving pain-related outcomes, yet their effects on psychological flexibility have not been meta-analyzed. This systematic review and meta-an...
The Link Between Exposure to Traumatic Stress and Chronic Pain: The Mediation Effect of Hyperarousal Is Moderated by Sensitivity to Pain Traumatization [0.03%]
创伤应激暴露与慢性疼痛之间的联系：警觉性在疼痛创伤敏感性调节下的中介作用
Noga Gur,Ruth Defrin,Yana Beitelman et al.
Noga Gur et al.
Background: Posttraumatic stress disorder (PTSD) is highly comorbid with chronic pain. Yet, the effects of PTSD's seemingly opposing characteristics-hyperarousal and dissociation-on chronic pain are unclear. This study ex...