Cognitive Function in Patients With Complex Regional Pain Syndrome (CRPS) [0.03%]
复杂区域疼痛综合征(CRPS)患者的认知功能
S Liesto,T Aho,S K Jääskeläinen et al.
S Liesto et al.
Background: Complex Regional Pain Syndrome (CRPS) is characterised by pain, sensory, vasomotor, sudomotor, motor, and trophic symptoms, with cognitive symptoms also reported. This study aimed to examine the neuropsycholog...
Randomized Controlled Trial
European journal of pain (London, England). 2025 Jul;29(6):e70070. DOI:10.1002/ejp.70070 2025
Cluster-Randomised Controlled Trial of At-Home Virtual Reality for People With Chronic Musculoskeletal Pain on the Waiting List [0.03%]
慢性肌肉骨骼疼痛候诊患者的居家虚拟现实疗法集群随机对照试验
Syl Slatman,Lieke Heesink,Reinoud Achterkamp et al.
Syl Slatman et al.
Background: Virtual reality (VR) has been introduced as a novel intervention in chronic musculoskeletal pain (CMP) rehabilitation. However, much remains unknown about the effectiveness of VR for CMP. The aim of this study...
Randomized Controlled Trial
European journal of pain (London, England). 2025 Jul;29(6):e70073. DOI:10.1002/ejp.70073 2025
Varying Analgesic Effectiveness of Systemic and Central Intrathecal Administration of Cyclooxygenase-2 Inhibitors in Different Phases of Osteoarthritic Pain in Rats [0.03%]
大鼠骨关节炎痛不同阶段环氧化酶-2抑制剂全身和中枢腰段蛛网膜下腔给药镇痛效果的差异性研究
Chun-Sung Sung,Shi-Ying Huang,Hao-Jung Cheng et al.
Chun-Sung Sung et al.
Background: Osteoarthritis (OA) contributes to heightened pain perception by disrupting the normal function of peripheral nerves and spinal nociceptive circuits. Although selective cyclooxygenase-2 (COX-2) inhibitors redu...
Is Lifting Technique Related to Pain and Functional Limitation? A Replicated Single-Case Design Study of Five People With Lifting-Related Chronic Low Back Pain [0.03%]
抬举技术与疼痛和功能障碍有关吗？五名与抬举相关的慢性下腰痛患者的单例设计研究
Ivan Pui Hung Au,Nic Saraceni,Anne Smith et al.
Ivan Pui Hung Au et al.
Background: Chronic low back pain (CLBP) is often provoked by lifting activities, but the relationship between changes in lifting technique and clinical outcomes while undergoing intervention remains unclear. This study e...
What a Sham(e): Sham-Controlled Conditioned Pain Modulation Effects on Pressure but Not Heat Pain Thresholds in Healthy Volunteers [0.03%]
欺骗控制的条件痛觉调制对健康志愿者的压力但不是热痛阈的影响是一种耻辱（不好意思用shame双关意义的字面翻译，但是觉得不好意思这个语境下更有感觉）
Madeleine Hau,Laura Sirucek,Iara De Schoenmacker et al.
Madeleine Hau et al.
Background: Conditioned pain modulation (CPM) is a well-established experimental paradigm to study descending pain modulation in humans, measuring the pain modulatory effect of a painful conditioning stimulus (CS) on a pa...
Patient Characteristics and Changes in Long-Term Opioid Use Among Patients With Non-Cancer Pain in Dutch Primary Care 2013-2022: A Population-Based Cohort Study [0.03%]
荷兰基层医疗中2013年至2022年非癌痛患者长期使用阿片类药物的患者特征及变化：基于人群的队列研究
Loes de Kleijn,Laura Struik,Hanneke J B M Rijkels-Otters et al.
Loes de Kleijn et al.
Background: Pain guidelines recommend de-prescribing long-term opioid treatment (LTOT) in non-cancer pain for reasons of risk-benefit balance. However, the prevalence and changes over time with regard to LTOT in patients ...
Breast Cancer Cell Lines AT-3 and E0771 Decrease Mechanical and Cold Sensitivity, Along With Oestrous Cycle and Inflammatory Marker Alterations, in Wild-Type C57BL/6J Female Mice [0.03%]
乳腺癌细胞系AT-3和E0771降低机械和冷敏感性，以及野生型C57BL/6J雌性小鼠发情周期和炎症标志物的改变
Robert C Barnes,Satish Banjara,Ava G Oliver et al.
Robert C Barnes et al.
Background: Breast cancer represents the most common cancer diagnosis and the leading cause of cancer-related death in women. Cancer is also associated with pain and changes in both tactile and temperature sensitivity tha...
A Linguistic Analysis of Future Perceptions of Parents of Adolescents With Complex Regional Pain Syndrome and Parents of Pain-Free Peers [0.03%]
复杂区域疼痛综合征青少年及其无痛同伴父母对未来感知的言语分析
Amy Parkinson,Line Caes,Emma Fisher et al.
Amy Parkinson et al.
Background: Complex regional pain syndrome (CRPS) is a chronic pain condition which typically affects a body extremity and occurs more frequently from the onset of adolescence. Parents of adolescents with chronic pain rep...
Assessing the Impact of Pharmacist-Led Interventions in an Academic Pain Clinic: Clinical Outcomes and Interprofessional Insights [0.03%]
药师领导的干预措施在学术性疼痛诊所的影响评估：临床结局与专业合作见解
V Arcani,D Protzenko,J Henri et al.
V Arcani et al.
Background: Polypharmacy is common among people living with chronic pain. This study aimed to evaluate the clinical impact of pharmacist-led medication reviews (MRs) in a pain clinic and to explore the perceptions of the ...
Loss of Glutaminase 1 in Small Sensory Neurons Prevents Nerve Injury Induced Mechanical Allodynia: Insights From Conditional Knockout Mice [0.03%]
小感觉神经元中谷氨酰胺酶1丢失可预防神经损伤诱导的机械性异常痛：条件性基因敲除小鼠研究的新发现
Anabel Martínez-Padilla,Javier Márquez,Miguel Á Huerta et al.
Anabel Martínez-Padilla et al.
Background: Glutamate, the primary neurotransmitter released by nociceptors, is predominantly synthesised by the enzyme Glutaminase 1 (GLS1). The involvement of GLS1 in pain pathways is well supported, as Gls1 heterozygou...