Suzanne M Mugie,Marc A Benninga,Carlo Di Lorenzo
Suzanne M Mugie
We aimed to review the published literature regarding the epidemiology of constipation in the general paediatric and adult population and to assess its geographic, gender and age distribution, and associated factors. A search of the Medline...
Chronic constipation. Preface [0.03%]
慢性便秘 序言
M A Benninga,S M Scott
M A Benninga
Hubert Louis,Jacques Devière
Hubert Louis
Due to its large prevalence, gastro-oesophageal reflux disease is an ideal target for companies developing medical devices designed to cure reflux. Indeed, because medications leave part of the patients unsatisfied, there is a potential pla...
Treatment of GERD complications (Barrett's, peptic stricture) and extra-oesophageal syndromes [0.03%]
GERD并发症（巴雷特食管、胃食管狭窄）及食管外综合征的治疗
Ajay Bansal,Peter J Kahrilas
Ajay Bansal
Apart from typical reflux symptoms and oesophagitis, the clinical presentation of GERD can be dominated by mucosal complications of reflux (Barrett's oesophagus, oesophageal adenocarcinoma, Peptic structure) or by extra-oesophageal syndrome...
Lars Lundell
Lars Lundell
Surgery should always be looked upon as complementary to medical therapy in the long-term management of patients with chronic GORD. Available medical therapies are effective and adequate for the control of disease manifestations in the grea...
Frank Zerbib
Frank Zerbib
Approximately 20-30% of patients with gastro-oesophageal reflux symptoms report inadequate symptom relief while on PPI therapy. Persisting acid or non-acid reflux can be demonstrated in 40-50% of them suggesting that there is room for anti-...
Tiberiu Hershcovici,Ronnie Fass
Tiberiu Hershcovici
Patients with gastro-esophageal reflux disease (GERD) who are not responding to proton pump inhibitors (PPIs) given once daily are very common. These therapy-resistant patients have become the new face of GERD in clinical practice in the la...
Short and long-term PPI treatment for GERD. Do we need more-potent anti-secretory drugs? [0.03%]
短程和长程PPI治疗GERD的疗效。我们需要更强的抑酸药物吗？
Stanislas Bruley des Varannes,Emmanuel Coron,Jean-Paul Galmiche
Stanislas Bruley des Varannes
Because the reflux of the acidic gastric content into the esophagus plays a major role in the pathogenesis of symptoms of GERD and lesions of erosive esophagitis, acid suppression with a proton pump inhibitor (PPI) is currently the mainstay...
J Labenz
J Labenz
Extra-oesophageal symptoms are common in patients with GORD, but a causal relationship is the exception rather than the rule. In the absence of specific diagnostic procedures capable of identifying patients who might respond to antireflux t...
Y C Chua,Qasim Aziz
Y C Chua
Gastro-oesophageal reflux disease (GORD) is common and often associated with unpleasant symptoms requiring utilisation of health care resource. While in the majority of patients symptom resolution occurs with acid suppressant therapy, in a ...