Benjamin H Mullish,Gianluca Ianiro
Benjamin H Mullish
Treatment sequencing in inflammatory bowel disease: Towards clinical precision medicine [0.03%]
炎症性肠病的治疗顺序：走向临床精准医疗
Léa Sequier,Bénédicte Caron,Sailish Honap et al.
Léa Sequier et al.
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, raise ongoing challenges in clinical management due to their variable courses and impact on patient quality of life. The emergence of advanced therapies, from bi...
Jacopo Fanizza,Ilaria Faggiani,Mariangela Allocca et al.
Jacopo Fanizza et al.
Biological therapies have revolutionized the management of inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Among these, biosimilars and biobetters represent a growing area of therapeutic develop...
Fabrizio Fanizzi,Ferdinando D&#x;Amico,Laurent Peyrin-Biroulet et al.
Fabrizio Fanizzi et al.
Inflammatory bowel diseases' traditional management focused primarily on symptom control, often failing to prevent long-term complications such as disease progression, disabilities, hospitalizations and surgeries. The introduction of biolog...
Reaching the therapeutic ceiling in IBD: Can Advanced Combination Treatment (ACT) offer a solution? [0.03%]
IBD治疗达到瓶颈时：高级联合治疗(ACT)能否提供解决方案？
Virginia Solitano,Jurij Hanžel,Maria Manuela Estevinho et al.
Virginia Solitano et al.
The term Advanced Combination Treatment (ACT) involves the combination of at least two biologics or the use of a biologic with a small molecule drug, each with different mechanisms of action. This narrative review evaluates the current evid...
The role of diet in inflammatory bowel disease: A comprehensive review of the literature [0.03%]
饮食在炎症性肠病中的作用：文献全面回顾
Ilaria Faggiani,Jacopo Fanizza,Sara Massironi et al.
Ilaria Faggiani et al.
Diet is increasingly recognized as a modifiable factor in the pathogenesis and management of inflammatory bowel disease (IBD), particularly in mild to moderate cases. While most evidence comes from pediatric studies, adult data, especially ...
Andrea Vignali,Pierpaolo Sileri
Andrea Vignali
Background: Restorative proctocolectomy with ileoanal pouch is the standard procedure in ulcerative colitis patients with medical refractory disease, dysplasia or in selected patients with Crohn's disease. The advent of b...
Natália Sousa Freitas Queiroz,Federica Furfaro
Natália Sousa Freitas Queiroz
Management of inflammatory bowel disease (IBD) during pregnancy requires a delicate balance to ensure the health of both mother and fetus. This chapter addresses key considerations, including preconception counseling, safe therapeutic optio...
"Unraveling the mysteries of IBD: Innovations and insights into the management of Crohn's disease and ulcerative colitis" [0.03%]
“解开IBD之谜：克罗恩病和溃疡性结肠炎管理的创新与见解”
Ferdinando D&#x;Amico,Sarah Bencardino,Silvio Danese
Ferdinando D&#x;Amico
Clelia Cicerone,Paulo Gustavo Kotze
Clelia Cicerone
Perianal fistulas are a common complication of Crohn's disease (CD), affecting approximately 40 % of patients. Fistulas develop because of sustained transmural inflammation of the bowel wall. Despite advances in treatment, one-third of pati...