Melitta Penz-Österreicher,Christoph H Österreicher,Michael Trauner
Melitta Penz-Österreicher
Autoimmune and cholestatic liver disease account for a significant part of end-stage liver disease and are leading indications for liver transplantation. Especially cholestatic liver diseases (primary biliary cirrhosis and primary sclerosin...
Ramon Bataller,Krista Rombouts,José Altamirano et al.
Ramon Bataller et al.
Both alcoholic and nonalcoholic steatohepatitis are relevant causes of cirrhosis and liver-related mortality. Alcohol abuse represents a major health problem in many countries, and liver disease is considered one of the most relevant causes...
Vincenza Calvaruso,Antonio Craxì
Vincenza Calvaruso
In the last years, several studies have been performed with the aim to evaluate the real impact of antiviral treatments on fibrosis progression in patients with chronic viral hepatitis. The main goal of therapy in patients with chronic hepa...
Liver fibrogenic cells [0.03%]
肝纤维化细胞学
Stuart J Forbes,Maurizio Parola
Stuart J Forbes
Liver fibrogenic cells are a heterogenous population of cells that include α-smooth muscle actin positive myofibroblasts (MFs). MFs promote the progression of chronic liver diseases (CLDs) towards cirrhosis. MFs are highly proliferative an...
Ursula E Lee,Scott L Friedman
Ursula E Lee
Multiple etiologies of liver disease lead to liver fibrosis through integrated signaling networks that regulate the deposition of extracellular matrix. This cascade of responses drives the activation of hepatic stellate cells (HSCs) into a ...
Foreword to liver fibrosis [0.03%]
肝纤维化前言
Massimo Pinzani
Massimo Pinzani
B P W van Wunnik,C G M I Baeten,B R Southwell
B P W van Wunnik
Constipation is a frequently occurring digestive ailment that is usually treated conservatively. Neuromodulation is altering function of an organ by altering neural activity. This paper reviews methods of neuromodulation used to treat const...
Marc A Levitt,Kellie L Mathis,John H Pemberton
Marc A Levitt
Functional constipation is one of the most common gastrointestinal disorders. In both children and adults, most patients are managed conservatively with good results. In this review, we focus on the surgical approach to constipation. Patien...
Satish S C Rao
Satish S C Rao
Dyssynergic defecation is common and affects up to one half of patients with chronic constipation. This acquired behavioural problem is due to the inability to coordinate the abdominal and pelvic floor muscles to evacuate stools. Today, it ...
J Tack
J Tack
In this article, traditional and novel therapies for chronic constipation are reviewed. Traditional laxatives are effective at inducing bowel movements, but efficacy in long-term management and efficacy on constipation-associated abdominal ...