The landscape of immune monitoring in CAR-T cell therapy: A comprehensive review and survey study by the Cellular Therapy and Immunobiology Working Party of the EBMT [0.03%]
CAR-T细胞治疗中免疫监测的现状:EBMT细胞治疗和免疫生物学工作组的全面回顾与调查研究
Simona Pagliuca,Florent Malard,Jarl E Mooyaart et al.
Simona Pagliuca et al.
Immune monitoring of cell therapies is a complex and evolving topic, particularly in the rapid expanding field of chimeric antigen receptor T (CAR-T) cell applications. Defining essential, recommended, and optional immune monitoring data po...
Classic Hodgkin lymphoma: Pathobiological features that impact emerging therapies [0.03%]
经典霍奇金淋巴瘤:影响新兴疗法的病理生物学特征
Mohamed Nazem Alibrahim,Annunziata Gloghini,Antonino Carbone
Mohamed Nazem Alibrahim
Classic Hodgkin lymphoma (cHL) is defined by distinctive Hodgkin Reed-Sternberg (HRS) cells, which are CD30+/CD15+ multinucleated tumor cells lacking typical B-cell markers. These cells comprise
PET scan for the detection of histological transformation of follicular lymphoma: A systematic review of diagnostic performance [0.03%]
正电子发射计算机体层摄影对滤泡淋巴瘤活检转化的诊断性能的系统评价
Marc Sorigue,Milos Miljkovic,Pablo Mozas
Marc Sorigue
The strength of evidence supporting use of PET in the evaluation of suspected histological transformation (HT) of follicular lymphoma (FL) is unknown. We conducted a systematic review of studies reporting the diagnostic performance of ≥1 P...
BTKi-induced cardiovascular toxicity in CLL: Risk mitigation and management strategies [0.03%]
慢性淋巴细胞白血病患者接受BTK抑制剂诱导的心血管毒性:风险评估与管理策略
Sofija Kozarac,Vojin Vukovic,Michael Fradley et al.
Sofija Kozarac et al.
Targeted therapies, consisting of Bruton tyrosine kinase inhibitors (BTKis) or BCL-2 inhibitors, are the mainstay of contemporary treatments for chronic lymphocytic leukemia (CLL). The most common adverse effects (AEs) of BTKis are fatigue,...
Radiotherapeutics, clonal hematopoiesis, and risk of hematologic malignancies: The good, the bad, the ugly [0.03%]
放疗、克隆型造血和血液系统恶性肿瘤风险:好坏美丑优劣论
Catherine H Marshall,Emmanuel S Antonarakis,Mrinal M Patnaik
Catherine H Marshall
While radiotherapeutics have demonstrated significant clinical benefit across multiple cancer types including thyroid cancer, neuroendocrine tumors, and prostate cancer, hematological toxicities can be frequent and challenging. It remains u...
Corrigendum to "Impact of transcranial Doppler screening on stroke prevention in children and adolescents with sickle cell disease: A systematic review and meta-analysis" [Blood Reviews (2024) 101253] [0.03%]
关于“经颅多普勒筛查对镰状细胞病儿童和青少年卒中预防的影响:系统回顾和meta分析”的勘误(发表于Blood Reviews (2024) 101253)
Danielle Guy,Robert Bagnall,Rebecca L Morgan et al.
Danielle Guy et al.
Published Erratum
Blood reviews. 2025 Jan 17:101258. DOI:10.1016/j.blre.2025.101258 2025
Application of thrombopoietic agents in cancer therapy-induced thrombocytopenia: A comprehensive review [0.03%]
血小板生成素药物在癌症治疗诱导的血小板减少症中的应用:综述
Junyang Mei,Feng Jiao,Yiping Li et al.
Junyang Mei et al.
Cancer therapy-induced thrombocytopenia (CT-IT) is one of the most common hematological toxicities of anti-cancer therapy, often leading to treatment dose reduced, postponed, or treatment plans altered or even discontinued. Thrombopoietin (...
Impact of transcranial Doppler screening on stroke prevention in children and adolescents with sickle cell disease: A systematic review and meta-analysis [0.03%]
颅内多普勒筛查对镰状细胞病青少年及儿童预防中风的影响:系统回顾和.meta.分析
Danielle Guy,Robert Bagnall,Rebecca L Morgan et al.
Danielle Guy et al.
Background: Children with sickle cell disease (SCD) have increased stroke risk, identifiable by elevated velocities on transcranial Doppler (TCD). This review assessed the impact of TCD screening on stroke, mortality, qua...
Host-directed therapies modulating innate immunity against infection in hematologic malignancies [0.03%]
针对造血系统恶性肿瘤感染的宿主导向治疗:调节先天免疫功能疗法
Qiong Wang,Kristján Hermannsson,Egill Másson et al.
Qiong Wang et al.
Patients with hematologic malignancies (HM) are highly susceptible to bloodstream infection (BSI), particularly those undergoing treatments such as chemotherapy. A common and debilitating side effect of chemotherapy is oral and intestinal m...
Neuro-toxicities of chemo- and immune-therapies in haematologic malignancies: from mechanism to management [0.03%]
化疗和免疫治疗在血液系统恶性肿瘤中的神经毒性:从机制到管理
David Kegyes,Vlad Moisoiu,Catalin Constantinescu et al.
David Kegyes et al.
Chemo- and immune therapies administered to treat haematologic malignancies frequently cause neurologic injury. The adverse events range from mild cognitive impairment and headaches to severe conditions such as seizures, stroke and encephal...