The Lebanese national patient blood management guidelines: A new page in the medical practice [0.03%]
黎巴嫩国家患者血液管理指南：医学实践的新篇章
Ali T Taher,Rita Feghali,Hanadi Samaha et al.
Ali T Taher et al.
Patient blood management (PBM) is a patient-centered, systematic, evidence-based approach to improve patient outcomes by managing and preserving a patient's own blood, while promoting patient safety and empowerment. Globally, PBM guidelines...
Targeting CD38 in immune thrombocytopenia: Rationale and a scoping review of daratumumab [0.03%]
靶向CD38治疗免疫性血小板减少症：达雷木单抗的合理性及综述分析
Abdulrahman F Al-Mashdali,Ayman Abdullah Dalol,Leen Haj Saleh et al.
Abdulrahman F Al-Mashdali et al.
Immune thrombocytopenia (ITP) remains therapeutically challenging in patients with refractory or relapsed disease despite expanding second-line options. Increasing evidence implicates autoreactive plasma cells in treatment resistance, provi...
Ana C Glembotsky,Nora V Butta,José M Bastida et al.
Ana C Glembotsky et al.
Platelets are small anucleate blood cells derived from megakaryocytes, essential for hemostasis and involved in thrombosis, inflammation, immunity, and tissue repair. Their production depends on tightly regulated processes of megakaryopoies...
AI for the assessment and discovery of morphological-molecular biomarker relationships in hematologic malignancies [0.03%]
基于人工智能的血液系统恶性肿瘤形态学-分子标志物关系评估和发现模型
Ignacio Hernández-Abad,Raquel Ancos-Pintado,Ana Mendoza et al.
Ignacio Hernández-Abad et al.
Artificial intelligence (AI) is transforming morphological assessment in hematologic malignancies by enabling automated cell classification, detection of disease-specific features, and prediction of genetic alterations from blood and bone m...
Challenges in the treatment of adolescent and young adult acute lymphoblastic leukemia: A comprehensive review [0.03%]
青少年及青年人急性淋巴细胞白血病治疗的挑战：全面综述
Madelyn Burkart,Shira Dinner
Madelyn Burkart
Advancements in the treatment of adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL) (AYA-ALL) have resulted in significant survival improvements over the last decade, however AYA patients continue to face worse outco...
Clostridioides difficile infection in non-transplanted adults with haematological malignancy: Systematic review and meta-analysis on behalf of European Conference on Infections in Leukemia (ECIL) and Infectious Diseases Working Party (IDWP) of the European Society for Blood and Marrow Transplantation (EBMT) [0.03%]
难辨梭菌在非移植血液系统恶性肿瘤成人患者中的感染：欧洲白血病感染大会（ECIL）和欧洲骨髓移植协会（EBMT）感染性疾病工作委员会的系统性回顾及 meta 分析
Chiara Oltolini,Agnieszka Piekarska,Alessio Signori et al.
Chiara Oltolini et al.
Clostridioides difficile infection (CDI) is a frequent complication in patients with haematological malignancies (HM). No meta-analysis on its incidence and outcomes in non-transplanted adults with HM is available. Pubmed/Medline database w...
Supportive strategies in thrombocytopenia: Platelet transfusion and beyond [0.03%]
特异性的血小板减少症支持性策略：输注血小板及其他疗法
Tomás José González-López,David J Kuter,Drew Provan
Tomás José González-López
Thrombocytopenia is a frequent hematological disorder associated with an increased risk of bleeding across diverse clinical settings. Supportive management aims to prevent hemorrhagic complications, relieve symptoms, and address underlying ...
Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome): A practical compartment-based review [0.03%]
皮肤T细胞淋巴瘤（蕈样肉芽肿和塞扎里综合征）的分隔诊断及治疗综述
Pablo Mozas,Andrea Combalia,Gabriela Antelo et al.
Pablo Mozas et al.
Primary cutaneous lymphomas are a heterogeneous group of lymphoid neoplasms with predominant skin involvement, among which mycosis fungoides (MF) and Sézary syndrome (SS) are the most frequent and clinically challenging entities. This narr...
Dysbiosis and immunothrombosis - How platelets and the gut microbiome interact [0.03%]
肠菌失调与免疫血栓形成——如何从血小板和肠道微生物的角度进行交互研究
Gerard Gurumurthy,Juditha Gurumurthy,Samantha Gurumurthy et al.
Gerard Gurumurthy et al.
Platelets are classically recognised for their role in haemostasis and thrombosis. They are now increasingly recognised as modulators of the immune system, referred to as immunothrombosis, and are thought to be closely associated with the g...
Immunotherapy in acute myeloid leukemia: The antibodies, TriKEs, and CARs on the arduous road to cure [0.03%]
急性髓系白血病的免疫疗法：通向治愈的艰辛之路上的抗体、TriKE 和 CAR
B Adhikari,M R Litzow,A L Dias
B Adhikari
Acute myeloid leukemia (AML) is a complex, heterogeneous and aggressive hematopoietic clonal disorder with limited curative options beyond allogeneic stem cell transplantation. The disease presents significant challenges due to high relapse...