Biomarkers of joint and bone diseases, and their associations to haemophilic arthropathy in people with haemophilia: A first systematic review [0.03%]
关节和骨病的生物标志物及其与血友病患者血友病性关节病变的相关性：首次系统评价
M Piccand,A Schmidt,H Stephan et al.
M Piccand et al.
Background: Despite therapeutic progress, haemophilic arthropathy persists due to recurrent haemarthrosis. With joint preservation as a central objective, sensitive and standardised biomarkers are needed. ...
What population-based databases reveal about equity in access to hematopoietic cell transplant and cellular therapy [0.03%]
人群数据库揭示的造血细胞移植和细胞治疗获取公平性问题
Sanghee Hong,Manuel Ricardo Espinoza-Gutarra,Rahul Shah et al.
Sanghee Hong et al.
Background: Large population-based databases are increasingly used to study access to hematopoietic cell transplantation (HCT) and chimeric antigen receptor T-cell (CAR-T) therapy. ...
A tale of two sites - Distinct spatial differences between bone marrow and extramedullary AML [0.03%]
骨髓和骨髓外AML的差异性空间分布规律——对两例患者的剖析
Hossein Emami,Annette I Garbe,Karin Huber et al.
Hossein Emami et al.
Acute myeloid leukemia (AML) is the most common acute leukemia in adults and remains associated with poor overall survival. Beyond genetic factors in the bone marrow (BM) that drive clonal evolution, leukemic progression, immune evasion, an...
Treating large B-cell lymphoma: Current strategies and unmet needs across community and academic settings [0.03%]
大B细胞淋巴瘤的治疗：社区和学术界环境下的当前策略及未竟需求
Tara Graff,Edward Pearson,Sairah Ahmed et al.
Tara Graff et al.
Therapeutic advances in large B-cell lymphoma (LBCL) are rapidly emerging, but their development and availability are largely concentrated in academic centers. Most patients receive care within community health systems where more limited re...
Raffaella Cassano Cassano,Rahul Banerjee,Aimaz Afrough et al.
Raffaella Cassano Cassano et al.
The assessment of minimal residual disease (MRD) is an important prognostic factor in hematologic malignancies, including multiple myeloma (MM). Historically defined as cancer cells undetectable by conventional morphology, MRD is now more a...
Javiera Benitez-Navarro,Constanza Sanhueza-Andrade,Carolina Figueroa et al.
Javiera Benitez-Navarro et al.
Repeat blood donation may progressively reduce iron stores, although the clinical relevance of biochemical iron depletion in otherwise healthy donors remains debated. This PRISMA-based systematic review and meta-analysis evaluated iron depl...
Artificial intelligence applications in thrombotic thrombocytopenic Purpura: A systematic review of diagnostic, risk stratification, and prognostic models [0.03%]
人工智能在血栓性血小板减少性紫癜中的应用：诊断、风险分层和预后模型的系统评价
Hissa Mohamed Al-Kuwari,Deema Al-Hamed,Amna Al-Balushi et al.
Hissa Mohamed Al-Kuwari et al.
Thrombotic thrombocytopenic purpura (TTP) is an uncommon but life-threatening thrombotic microangiopathy (TMA) caused by severe ADAMTS13 deficiency. Early diagnosis and prompt initiation of plasma exchange are critical; however, access to r...
Antibacterial, antifungal and antiviral prophylaxis and vaccination strategies in adult patients with acute myeloid and promyelocytic leukemia: An expert panel consensus from the GIMEMA group [0.03%]
成人急性髓系白血病和早幼粒细胞白血病的抗细菌、抗真菌和抗病毒预防及疫苗接种策略：GIMEMA小组专家共识意见
Francesco Marchesi,Corrado Girmenia,Enrico Maria Trecarichi et al.
Francesco Marchesi et al.
Infections are a leading cause of morbidity, mortality, and treatment delays in AML and APL. While international guidelines emphasize intensive chemotherapy, they often overlook less intensive regimens, rely on outdated data, and ignore ris...
The Lebanese national patient blood management guidelines: A new page in the medical practice [0.03%]
黎巴嫩国家患者血液管理指南：医学实践的新篇章
Ali T Taher,Rita Feghali,Hanadi Samaha et al.
Ali T Taher et al.
Patient blood management (PBM) is a patient-centered, systematic, evidence-based approach to improve patient outcomes by managing and preserving a patient's own blood, while promoting patient safety and empowerment. Globally, PBM guidelines...
Targeting CD38 in immune thrombocytopenia: Rationale and a scoping review of daratumumab [0.03%]
靶向CD38治疗免疫性血小板减少症：达雷木单抗的合理性及综述分析
Abdulrahman F Al-Mashdali,Ayman Abdullah Dalol,Leen Haj Saleh et al.
Abdulrahman F Al-Mashdali et al.
Immune thrombocytopenia (ITP) remains therapeutically challenging in patients with refractory or relapsed disease despite expanding second-line options. Increasing evidence implicates autoreactive plasma cells in treatment resistance, provi...