An Integrative Morphomolecular Classification System of Gastric Carcinoma With Distinct Clinical Outcomes [0.03%]
具有不同临床转归的胃癌整合的形态分子分类系统
Jia-Huei Tsai,Yung-Ming Jeng,Kuo-Hsing Chen et al.
Jia-Huei Tsai et al.
A robust morphomolecular classification system for gastric carcinoma is required. A 4-tier morphologic classification is proposed, including diffuse, intestinal, tubular, and lymphoid types. A tissue microarray for mismatch repair immunohis...
Epstein-Barr Virus-negative Marginal Zone Lymphoma as an Uncommon Form of Monomorphic Posttransplant Lymphoproliferative Disorder [0.03%]
移植后淋巴增生性疾病的一种不常见的形式：边缘区淋巴瘤EB病毒阴性
Pallavi Galera,Richard Flavin,Natasha M Savage et al.
Pallavi Galera et al.
Monomorphic posttransplant lymphoproliferative disorders have been defined as lymphoid or plasmacytic proliferations that fulfill criteria for one of the B-cell or T/NK-cell neoplasms recognized in immunocompetent hosts in the current WHO C...
Lisa M Rooper,Nasir Uddin,Jeffrey Gagan et al.
Lisa M Rooper et al.
Molecular analysis has reshaped the landscape of high grade sinonasal tumors by defining novel entities and identifying recurrent mutations in established tumor types. However, sinonasal teratocarcinosarcoma (TCS), a rare and aggressive tum...
Mutational Analysis Reinforces the Diagnosis of Nodal Marginal Zone Lymphoma With Robust PD1-positive T-Cell Hyperplasia [0.03%]
突变分析可辅助具有明显的PD1阳性T细胞增生的 nodal marginal zone lymphoma（结外边缘区淋巴瘤）的诊断
Stephanie N Hurwitz,Gabriel C Caponetti,Lauren Smith et al.
Stephanie N Hurwitz et al.
Histopathologic Analysis of Signet-ring Cell Carcinoma In Situ in Patients With Hereditary Diffuse Gastric Cancer [0.03%]
遗传性弥漫型胃癌患者的原位印戒细胞癌的组织病理学分析
Yuta Tsugeno,Kaoru Nakano,Takeshi Nakajima et al.
Yuta Tsugeno et al.
Hereditary diffuse gastric cancer (HDGC) is a rare autosomal dominant syndrome associated with an increased risk of developing Laurén's diffuse-type gastric carcinoma and lobular breast carcinoma. Although signet-ring cell carcinoma (SRCC)...
Diagnostic Utility of LEF1 Immunohistochemistry in Differentiating Deep Penetrating Nevi From Histologic Mimics [0.03%]
LEF1免疫组化在鉴别深层穿透性雀斑样痣与组织病理学类似病变中的诊断价值
Shyam S Raghavan,Atif Saleem,Jennifer Y Wang et al.
Shyam S Raghavan et al.
Deep penetrating nevi (DPNs) are intermediate grade lesions which have the capacity to recur, metastasize, or progress to melanoma. Differentiating DPN from other melanocytic lesions including blue and cellular blue nevi can be diagnostical...
Andrew A Renshaw,Edwin W Gould
Andrew A Renshaw
Loss of MHC Class I Expression in HPV-associated Cervical and Vulvar Neoplasia: A Potential Mechanism of Resistance to Checkpoint Inhibition [0.03%]
人乳头瘤病毒相关宫颈和外阴肿瘤中MHC I类分子表达丧失：对免疫检查点抑制产生耐药性的潜在机制研究
Megan E Dibbern,Timothy N Bullock,Taylor M Jenkins et al.
Megan E Dibbern et al.
Tumor cell expression of major histocompatibility complex (MHC) class I is required for antigen presentation and adaptive immune recognition. Absent or diminished MHC class I expression is thought to contribute to immunotherapeutic resistan...
SOX6 is a Novel Immunohistochemical Marker for Differential Diagnosis of Epithelioid Mesothelioma From Lung Adenocarcinoma [0.03%]
SOX6是一种新的免疫组化标记物可区分肺腺癌和 epithelioid 型间皮瘤
Takahiro Kambara,Vishwa J Amatya,Kei Kushitani et al.
Takahiro Kambara et al.
The differential diagnosis of epithelioid mesothelioma from lung adenocarcinoma using immunohistochemistry is improving. However, immunohistochemical markers with high sensitivity and specificity have yet to be identified. In this study, we...
Intravascular Lobular Capillary Hemangioma (Intravascular Pyogenic Granuloma): A Clinicopathologic Study of 40 Cases [0.03%]
血管内皮细胞淋巴样血管内皮瘤（血管内炎性假瘤）的临床病理研究40例
Josephine K Dermawan,Jennifer S Ko,Steven D Billings
Josephine K Dermawan
Intravascular lobular capillary hemangioma (ILCH), or intravascular pyogenic granuloma, is relatively rare and likely underrecognized. We reviewed all ILCH cases from our institution confirmed pathologically from 2006 to 2019. Immunostains ...