A Morphologic and Immunohistochemical Comparison of Nuclear β-Catenin Expressing Testicular Sertoli Cell Tumors and Pancreatic Solid Pseudopapillary Neoplasms Supporting Their Continued Separate Classification [0.03%]
核β-连环蛋白阳性睾丸支持细胞瘤和胰腺实体假乳头状瘤的形态学和免疫组化比较研究，支持其为不同的肿瘤类型
Chia-Sui Kao,Thomas M Ulbright
Chia-Sui Kao
Some recent reports suggested that many Sertoli cell tumors, not otherwise specified (SCTs-NOS) of the testis were analogs of the solid pseudopapillary neoplasm (SPN) of the pancreas. One of the most relied on pieces of information for this...
The Width of Invasion in Malignant Melanoma Is a Novel Prognostic Feature That Accounts for Outcome Better Than Breslow Thickness [0.03%]
恶性黑色素瘤侵袭宽度是比布里斯奥厚度更有预后价值的指标
Gerald Saldanha,Aarushi Khanna,Marie O&#x;Riordan et al.
Gerald Saldanha et al.
Breslow thickness (BT) is the cornerstone of malignant melanoma staging. However, to our knowledge no-one has ever assessed the horizontal width of invasion, measured microscopically, as a prognostic feature. This was investigated as a prog...
Acquired Cystic Kidney Disease-associated Renal Cell Carcinoma (ACKD-RCC) Harbor Recurrent Mutations in KMT2C and TSC2 Genes [0.03%]
获得性肾囊性疾病相关肾细胞癌（ACKD-RCC）中KMT2C和TSC2基因反复发生突变
Abhishek Shah,Priti Lal,Erik Toorens et al.
Abhishek Shah et al.
Individuals with acquired cystic kidney disease (ACKD) in the setting of end-stage renal disease (ESRD) have a high risk of developing renal cell carcinoma (RCC). ACKD-RCC is considered a distinct renal neoplasm in the International Society...
A Molecular Reappraisal of Glomus Tumors and Related Pericytic Neoplasms With Emphasis on NOTCH-gene Fusions [0.03%]
NOTCH基因融合的血管周细胞肿瘤和相关神经纤维瘤病的分子病理学研究
Narasimhan P Agaram,Lei Zhang,Achim A Jungbluth et al.
Narasimhan P Agaram et al.
Glomus tumors (GTs), together with myofibroma (MF), myopericytoma (MP), and angioleiomyoma (AL) are classified as members of the perivascular myoid family of tumors. The reported genetic abnormalities across these neoplasms is dissimilar, a...
PHOX2B Immunostaining: A Simple and Helpful Tool for the Recognition of Ganglionic Cells and Diagnosis of Hirschsprung Disease [0.03%]
PHOX2B免疫染色在神经元细胞识别和先天性巨结肠病诊断中的应用价值初探
Philippe Drabent,Arnaud Bonnard,Fabien Guimiot et al.
Philippe Drabent et al.
Hirschsprung disease (HD) is a congenital disorder of the enteric nervous system that occurs in ∼1 in 5000 live births. It is characterized by the absence of ganglionic cells (GCs) in the distal intestine. The diagnosis relies on the thoro...
Genomic and Immunophenotypic Landscape of Aggressive NK-Cell Leukemia [0.03%]
侵袭性NK细胞白血病的基因组和免疫表型谱特征
Siba El Hussein,Keyur P Patel,Hong Fang et al.
Siba El Hussein et al.
Aggressive natural killer-cell leukemia (ANKL) is a rare, lethal disease with pathologic features that are underdescribed in the literature, particularly in Western nations. In addition, although data on the molecular pathogenesis of ANKL h...
Neuroendocrine Cells Are Commonly Absent in the Intestinal Crypts in Autoimmune Enteropathy [0.03%]
自身免疫性肠病患者肠道隐窝神经内分泌细胞常见缺失
Hee Eun Lee,Lin Yuan,Tsung-Teh Wu
Hee Eun Lee
The absence of neuroendocrine (NE) cells in the intestinal mucosa in autoimmune enteropathy (AIE) has been occasionally reported. However, the status of NE cells has not been studied in detail in AIE. Small bowel and colonic biopsies were r...
Lower Rate of CTNNB1 Mutations and Higher Rate of APC Mutations in Desmoid Fibromatosis of the Breast: A Series of 134 Tumors [0.03%]
CTNNB1突变率低和APC突变率高：134例乳腺位局灶性纤维瘤病的病例系列研究
Emma Norkowski,Julien Masliah-Planchon,Sophie Le Guellec et al.
Emma Norkowski et al.
Desmoid fibromatosis (DF) is a rare, locally aggressive, nonmetastasizing fibroblastic/myofibroblastic tumor with a tendency to recur and an unpredictable clinical course. A "wait-and-see" policy is the new standard of care. DF are characte...
Inflammatory Myofibroblastic Tumor of the Uterus: An Immunohistochemical Study of 23 Cases [0.03%]
子宫炎性肌纤维母细胞瘤的免疫组化研究(23例报告)
Jennifer A Bennett,Sabrina Croce,Anna Pesci et al.
Jennifer A Bennett et al.
Inflammatory myofibroblastic tumors (IMT) of the uterus may be underrecognized as their morphology and immunophenotype may overlap with myxoid variants of uterine smooth muscle tumors and endometrial stromal tumors. Although ALK is a helpfu...
Jerome B Taxy,Thomas Cibull
Jerome B Taxy
Syphilis is a sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum that has been of public health concern for centuries. In the United States, it is currently a reportable disease and one which is recently gen...