Uterine Tumor Resembling Ovarian Sex Cord Stromal Tumor (UTROSCT): A Series of 3 Cases With Extensive Rhabdoid Differentiation, Malignant Behavior, and ESR1-NCOA2 Fusions [0.03%]
类似卵巢性索间质肿瘤的子宫肿瘤(UTROSCT):3例广泛横纹肌样分化、恶性行为和ESR1-NCOA2融合的病例系列分析
Jennifer A Bennett,Ricardo R Lastra,Julieta E Barroeta et al.
Jennifer A Bennett et al.
ESR1 and GREB1 fusions have recently been described in uterine tumor resembling ovarian sex cord tumor (UTROSCT). Thus far, recurrences have been documented in a subset of those harboring GREB1 fusions, but not in those with ESR1 rearrangem...
Synovial Sarcoma of the Female Genital Tract: A Protean Mimic of Müllerian Neoplasia [0.03%]
女性生殖道滑膜肉瘤:一种穆勒氏肿瘤的多形模仿者
David L Kolin,Christopher P Crum,Esther Baranov et al.
David L Kolin et al.
Synovial sarcoma most commonly occurs in the extremities but has rarely been described in the female genital tract. In this series, we describe the clinical, morphologic, immunohistochemical, and molecular features of 7 cases of vulvovagina...
Expanding the Molecular Spectrum of Secretory Carcinoma of Salivary Glands With a Novel VIM-RET Fusion [0.03%]
新的VIM-RER融合扩大了分泌性癌的分子谱范围——腮腺癌病例报告
Alena Skálová,Martina Banečkova,Lester D R Thompson et al.
Alena Skálová et al.
Background: Secretory carcinoma (SC), originally described as mammary analogue SC, is a predominantly low-grade salivary gland neoplasm characterized by a recurrent t(12;15)(p13;q25) translocation, resulting in ETV6-NTRK3...
HPV-independent Precursors Mimicking High-grade Squamous Intraepithelial Lesions (HSIL) of the Vulva [0.03%]
mimic HPV阴性的外阴高级别鳞状上皮内病变(HSIL)
Natalia Rakislova,Laia Alemany,Omar Clavero et al.
Natalia Rakislova et al.
Two etiopathogenic types of vulvar squamous cell carcinoma (VSCC) have been described: human papillomavirus (HPV)-associated and HPV-independent. Precursor lesions, frequently identified in the adjacent skin, are also distinct in the 2 type...
Helicobacter pylori Antigen But Not the Organism Is Occasionally Present Within Germinal Centers: Implications for Patient Management and Biology [0.03%]
幽门螺杆菌抗原而非细菌偶尔会出现在生发中心中:对患者管理和生物学的意义
Nya D Nelson,Rashmi Tondon,Danielle Fortuna et al.
Nya D Nelson et al.
Helicobacter pylori infection is present in two thirds of the world's population and induces a myriad of human diseases, ranging from gastritis to gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. Detection is critical ...
Myoepithelioma-like Hyalinizing Epithelioid Tumor of the Foot Harboring an OGT-FOXO1 Fusion [0.03%]
含有OGT-FOXO1融合基因的足部肌上皮瘤样透明细胞 epithelioid 瘤
Takashi Yorozu,Kiyotaka Nagahama,Takeshi Morii et al.
Takashi Yorozu et al.
PD-1 and PD-L1 Immunohistochemistry as a Diagnostic Tool for Classic Hodgkin Lymphoma in Small-volume Biopsies [0.03%]
小标本活检中PD-1和PD-L1免疫组织化学作为经典型霍奇金淋巴瘤的诊断工具
Ashley Volaric,Carlos E Bacchi,Alejandro A Gru
Ashley Volaric
It is becoming increasingly important to obtain detailed diagnostic information on small-volume tissue biopsies, such as core needle biopsies. This is particularly crucial in the workup and diagnosis of classic Hodgkin lymphoma (CHL) and ot...
Steatohepatitic Variant of Hepatocellular Carcinoma Is Associated With Both Alcoholic Steatohepatitis and Nonalcoholic Steatohepatitis: A Study of 2 Cohorts With Molecular Insights [0.03%]
基于分子见解的两项队列研究:肝细胞癌的肝硬化脂肪变性变异型与酒精性肝炎和非酒精性肝炎均相关
Jia Qin,Takaaki Higashi,Shigeki Nakagawa et al.
Jia Qin et al.
Steatohepatitic hepatocellular carcinoma (SH-HCC) is a variant of hepatocellular carcinoma (HCC) with established association with nonalcoholic steatohepatitis (NASH), while its association with alcoholic steatohepatitis (ASH) is unclear. W...
Plexiform Myofibroblastoma: Clinicopathologic Analysis of 36 Cases of a Distinctive Benign Tumor of Soft Tissue Affecting Mainly Children and Young Adults [0.03%]
Plexiform肌纤维母细胞瘤:主要影响儿童和青年人的软组织良性肿瘤36例的临床病理分析
David J Papke Jr,Alyaa Al-Ibraheemi,Christopher D M Fletcher
David J Papke Jr
The spectrum of benign superficial fibroblastic/myofibroblastic tumors continues to expand and includes entities such as plexiform fibrohistiocytic tumor, dermatomyofibroma and fibroblastic connective tissue nevus. Here, we describe a seemi...
Cathleen Matrai,Samaneh Motanagh,Susanna Mirabelli et al.
Cathleen Matrai et al.
Mixed endometrial carcinomas are defined as a combination of 2 or more distinct histologic subtypes, one of which must be a type II tumor comprising at least 5% of the tumor volume. The oncogenesis of these tumors remains unclear, particula...