Pleural Malignant Mesotheliomas Do Not Demonstrate SWItch/Sucrose Nonfermentable (SWI/SNF) Complex Deficiency [0.03%]
胸膜恶性间皮瘤并不显示SWItch/蔗糖非发酵(SWI/SNF)复合物缺乏症
He Zhen Ren,Basile Tessier-Cloutier,Julia R Naso et al.
He Zhen Ren et al.
Sclerosing Epithelioid Fibrosarcoma: A Distinct Sarcoma With Aggressive Features [0.03%]
硬化性上皮样纤维肉瘤:一种具有侵袭性的独特肉瘤类型
Laura M Warmke,Jeanne M Meis
Laura M Warmke
Since its original description in 1995, the concept of sclerosing epithelioid fibrosarcoma (SEF) as a distinctive tumor has evolved in the literature. Subsequent studies suggested that the presence of low grade fibromyxoid sarcoma (LGFMS)-l...
Aberrant GATA3 Staining in Prostatic Adenocarcinoma: A Potential Diagnostic Pitfall [0.03%]
前列腺腺癌中GATA3异常染色:潜在的诊断陷阱
Timothy M McDonald,Jonathan I Epstein
Timothy M McDonald
Distinguishing between poorly differentiated urothelial carcinoma and high-grade prostatic adenocarcinoma is a common challenge in genitourinary pathology, particularly when the tumor involves the bladder neck or prostatic urethra. Clinical...
CTNNB1 Mutations and Aberrant β-Catenin Expression in Ovarian Endometrioid Carcinoma: Correlation With Patient Outcome [0.03%]
卵巢子宫内膜样癌中CTNNB1突变和异常β-连环素表达与患者预后的相关性研究
Roman E Zyla,Ekaterina Olkhov-Mitsel,Yutaka Amemiya et al.
Roman E Zyla et al.
CTNNB1 mutations and aberrant β-catenin expression have adverse prognosis in endometrial endometrioid carcinoma, and recent evidence suggests a prognostic role of β-catenin in ovarian endometrioid carcinoma. Thus, we aimed to determine th...
Malignant Mesothelioma of the Peritoneum in Women: A Clinicopathologic Study of 164 Cases [0.03%]
女性腹膜恶性间皮瘤:164例临床病理研究
Anais Malpica,Elizabeth D Euscher,Mario L Marques-Piubelli et al.
Anais Malpica et al.
Malignant mesothelioma of the peritoneum in women is an uncommon tumor. In this study, we present the clinicopathologic features of 164 such cases seen in our institution over a period of 42 years (1974-2016). Clinical information, patholog...
Postchemotherapy Histiocyte-rich Pseudotumor Mimicking Residual Lymphoma: A Report of 11 Cases Correlating Clinicopathologic and Radiologic Findings [0.03%]
化疗后组织细胞丰富的假肿瘤模仿残留的淋巴瘤:11例病例报告关联临床病理和影像学检查发现
Hong Fang,Hubert H Chuang,Paolo Strati et al.
Hong Fang et al.
Postchemotherapy histiocyte-rich pseudotumor is a rare event in lymphoma patients and can cause elevated metabolic activity on positron emission tomography-computed tomography scan mimicking residual tumor. Here, we reported 11 lymphoma cas...
Neuroendocrine Carcinomas of the Gallbladder: A Clinicopathologic and Immunohistochemical Analysis of 34 Resected Cases [0.03%]
胆囊神经内分泌癌的临床病理和免疫组化分析
Sun Mi Lee,Chang Ohk Sung
Sun Mi Lee
Neuroendocrine carcinoma (NEC) is an aggressive malignant tumor that rarely arises from the gallbladder. Here, we investigated the clinicopathologic and immunohistochemical characteristics of 34 NECs of the gallbladder. The patients were pr...
Chromogranin A Expression in Rectal Neuroendocrine Tumors Is Associated With More Aggressive Clinical Behavior and a Poorer Prognosis [0.03%]
直肠神经内分泌肿瘤中嗜铬粒素A的表达与更恶性的临床行为及预后较差有关
Jisup Kim,Joo Young Kim,Eun Hye Oh et al.
Jisup Kim et al.
Although rectal neuroendocrine tumors (NETs) with an L-cell phenotype and small size are generally less clinically serious, the new 2019 World Health Organization (WHO) classification system has categorized all of these lesions as malignant...
Cutaneous Melanocytic Tumors With Concomitant NRASQ61R and IDH1R132C Mutations: A Report of 6 Cases [0.03%]
伴有NRASQ61R和IDH1R132C突变的皮肤黑色素细胞肿瘤:6例报道
Nicolas Macagno,Daniel Pissaloux,Heather Etchevers et al.
Nicolas Macagno et al.
We report a series of 6 melanocytic proliferations harboring both NRAS and IDH1 hotspot mutations. Clinically, there was no specific sex-ratio, ages ranged from 18 to 85 years, and the trunk and limbs were the most affected localizations. I...
Morphologic and Immunohistochemical Characteristics of Fluorescent In Situ Hybridization Confirmed TFE3-Gene Fusion Associated Renal Cell Carcinoma: A Single Institutional Cohort [0.03%]
荧光原位杂交确认的TFE3基因重排肾细胞癌的形态和免疫组化特点:单中心病例队列研究
Mahmut Akgul,Omer Saeed,David Levy et al.
Mahmut Akgul et al.
TFE3-fusion associated renal cell carcinoma (TFE3-RCC) accounts for up to 5% adults and 40% of childhood RCC. Their comprehensive immunohistochemical (IHC) profile in correlation to fluorescence in situ hybridization (FISH) testing and thei...