Primary Female Urethral Carcinoma: Proposed Staging Modifications Based on Assessment of Female Urethral Histology and Analysis of a Large Series of Female Urethral Carcinomas [0.03%]
女性尿道原发癌：基于女性尿道组织学评估和大量女性尿道癌分析对分期提出的修改建议
Manju Aron,Sanghui Park,Brett M Lowenthal et al.
Manju Aron et al.
Primary female urethral carcinoma is rare. Limited clinicopathologic information has hindered development of staging criteria in this disease. We analyzed 29 primary female urethral carcinoma resections from 3 academic medical centers to ch...
Chondroblastoma Expresses RANKL by RNA In Situ Hybridization and May Respond to Denosumab Therapy [0.03%]
软骨母细胞瘤通过RNA原位杂交表达RANKL，可能对地诺单抗治疗有反应
David I Suster,Pawel Kurzawa,Azfar Neyaz et al.
David I Suster et al.
Lesions of bone featuring osteoclast-like giant cells comprise a diverse group of entities, including giant cell tumor (GCT) of bone, chondroblastoma, and aneurysmal bone cyst, among others. The receptor activator of nuclear factor-κB liga...
ALK-positive Histiocytosis of the Breast: A Clinicopathologic Study Highlighting Spindle Cell Histology [0.03%]
乳腺ALK阳性组织细胞增多症的临床病理研究，着重于梭形细胞形态学
Jumpei Kashima,Masayuki Yoshida,Kenjiro Jimbo et al.
Jumpei Kashima et al.
Originally described as a systemic self-limiting disease in infancy, the spectrum of ALK-positive histiocytosis has recently been broadened to include localized diseases in older children and young adults. Despite different manifestations, ...
Comparison of RNA In Situ Hybridization and Immunohistochemistry Techniques for the Detection and Localization of SARS-CoV-2 in Human Tissues [0.03%]
RNA原位杂交与免疫组织化学技术在人类组织中检测和定位SARS-CoV-2的比较研究
Lucas R Massoth,Niyati Desai,Annamaria Szabolcs et al.
Lucas R Massoth et al.
Coronavirus disease-19 (COVID-19) is caused by a newly discovered coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although SARS-CoV-2 is visualized on electron microscopy, there is an increasing demand for widely ...
Clinicopathologic Features of Varicella Zoster Virus Infection of the Upper Gastrointestinal Tract [0.03%]
水痘-带状疱疹病毒感染上消化道的临床病理特征
Maria Mostyka,Jinru Shia,William L Neumann et al.
Maria Mostyka et al.
Reactivation of latent varicella zoster virus (VZV) may be limited to a dermatome or involve multiple organs, including the gastrointestinal tract. Although gastrointestinal manifestations of disseminated zoster have been likened to those o...
Malignant Peritoneal Mesothelioma Arising in Young Adults With Long-standing Indwelling Intra-abdominal Shunt Catheters [0.03%]
长期腹内留置分流导管的青壮年中的恶性腹膜间皮瘤
Tala Mujahed,Henry D Tazelaar,William R Sukov et al.
Tala Mujahed et al.
Only 50% to 70% of patients with mesothelioma report asbestos exposure. Other exposures (eg, radiation) play a role in some cases, but some patients have no obvious cause. We describe a series of patients with long-standing indwelling intra...
The Separation of Benign and Malignant Mesothelial Proliferations: New Markers and How to Use Them [0.03%]
良性与恶性间皮增生的区分：新的标志物及其使用方法
Andrew Churg,Julia R Naso
Andrew Churg
The separation of benign from malignant mesothelial proliferations is an important clinical but often a difficult morphologic problem. Over the last roughly 10 years a variety of new markers that aid in this separation have been published a...
High-grade Neuroendocrine Carcinomas of the Vulva: A Clinicopathologic Study of 16 Cases [0.03%]
外阴高级别神经内分泌癌的临床病理研究.Undefine16例.Undefine
Peter P Chen,Preetha Ramalingam,Isabel Alvarado-Cabrero et al.
Peter P Chen et al.
Vulvar high-grade neuroendocrine carcinomas (HGNECs) are rare and primarily thought to represent Merkel cell carcinoma (MCC). We present the clinicopathologic features of 16 such cases, the largest series to date. Patients were most often W...
DDIT3 Immunohistochemistry Is a Useful Tool for the Diagnosis of Myxoid Liposarcoma [0.03%]
DDIT3免疫组织化学是黏液样脂肪肉瘤诊断的有用工具
Jason V Scapa,Jeffrey M Cloutier,Shyam S Raghavan et al.
Jason V Scapa et al.
Myxoid liposarcoma is a malignant adipogenic neoplasm characterized by prominent arborizing capillaries, occasional lipoblasts, and primitive-appearing spindle cells in a myxoid background. A recurrent translocation in myxoid liposarcoma re...
Sertoli-Leydig Cell Tumors of the Ovary With Follicular Differentiation Often Resembling Juvenile Granulosa Cell Tumor: A Report of 38 Cases Including Comments on Sex Cord-Stromal Tumors of Mixed Forms (So-called Gynandroblastoma) [0.03%]
常似幼年型颗粒细胞瘤的卵巢单纯间质细胞瘤伴有滤泡样分化：38例病例报告及对混合性性索-间质肿瘤形式（所谓女男混杂瘤）的评论
Zehra Ordulu,Robert H Young
Zehra Ordulu
Thirty-eight ovarian Sertoli-Leydig cell tumors that contained follicles are described; in 33 of them follicles imparted a microscopic appearance resembling that of the juvenile granulosa cell tumor. The average age of the patients (28 y), ...