Secondary Involvement of the Uterine Cervix by Nongynecologic Neoplasms: A Detailed Clinicopathologic Analysis [0.03%]
非妇科肿瘤对子宫颈的二次侵犯：一项详细的临床病理分析
Gulisa Turashvili,Wesley R Samore,Esther Oliva et al.
Gulisa Turashvili et al.
Secondary involvement of the uterine cervix by nongynecologic neoplasms is rare accounting for 50.5) (P=0.01). Mean time to identification of cervical metastases was
Pseudocarcinomatous Squamous Hyperplasia Involving Bone: A Diagnostic Pitfall Mimicking Squamous Cell Carcinoma [0.03%]
涉及骨骼的假性癌鳞状增生：模拟鳞状细胞癌的一种诊断陷阱
Smiljana Spasić,Oleksandr N Kryvenko,Darcy A Kerr et al.
Smiljana Spasić et al.
Background: Pseudocarcinomatous squamous hyperplasia (PSH) within the bone is uncommon and closely mimics well-differentiated squamous cell carcinoma (SCC). It arises from cutaneous or mucosal surfaces and grows directly ...
BRG1, INI1, and ARID1B Deficiency in Endometrial Carcinoma: A Clinicopathologic and Immunohistochemical Analysis of a Large Series From a Single Institution [0.03%]
子宫癌中的BRG1,INI1和ARID1B缺乏：一项单机构大量病例的临床病理学与免疫组化分析
Atsushi Kihara,Yusuke Amano,Daisuke Matsubara et al.
Atsushi Kihara et al.
Switch/sucrose nonfermenting complex subunits, such as BRG1, INI1, and ARID1B, are inactivated in a subset of endometrial undifferentiated carcinoma and dedifferentiated carcinoma (DC). Limited information is currently available on their pr...
Langerhans Cell Histiocytosis Associated With Renal Cell Carcinoma Is a Neoplastic Process: Clinicopathologic and Molecular Study of 7 Cases [0.03%]
与肾细胞癌相关的兰格罕氏巨细包性病变是一种肿瘤性疾病：7例临床病理及分子研究
Abbas Agaimy,Michael Bonert,Asghar Naqvi et al.
Abbas Agaimy et al.
Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder composed of Langerhans cells admixed with reactive mononuclear and granulocytic cells, associated with prominent eosinophils. LCH is considered a neoplasm, driven in most ca...
Rare DICER1 and Absent FOXL2 Mutations Characterize Ovarian Juvenile Granulosa Cell Tumors [0.03%]
卵巢幼年颗粒细胞肿瘤的DICER1突变罕见而FOXL2突变缺失
Pauline Baillard,Catherine Genestie,Sabrina Croce et al.
Pauline Baillard et al.
FOXL2 somatic mutation occurs in a high percentage of ovarian adult granulosa cell tumors and DICER1 mutations in a high proportion of Sertoli-Leydig cell tumors. These mutations have only been studied in a limited number of juvenile granul...
IgG4-related Lymphadenopathy: A Comparative Study of 41 Cases Reveals Distinctive Histopathologic Features [0.03%]
IgG4相关的淋巴结病：对41个病例的比较研究揭示了显著的组织病理学特征
Jacob R Bledsoe,Judith A Ferry,Azfar Neyaz et al.
Jacob R Bledsoe et al.
Lymphadenopathy is common in patients with immunoglobulin G4-related disease (IgG4-RD). However, the described histopathologic features of IgG4-related lymphadenopathy have been shown to be largely nonspecific. In an attempt to identify fea...
Genomic Profiling Aids Classification of Diagnostically Challenging Uterine Mesenchymal Tumors With Myomelanocytic Differentiation [0.03%]
基因组谱分类有助于诊断具有肌黑色素细胞分化的子宫间叶肿瘤难题
Pier Selenica,Niamh Conlon,Carlene Gonzalez et al.
Pier Selenica et al.
Although diagnosis of high-grade uterine mesenchymal tumors (UMTs) exhibiting classic morphologic features is straightforward, diagnosis is more challenging in tumors in which prototypical features are poorly developed, focal, and/or coexis...
AKT1 Mutations in Peripheral Bronchiolar Papilloma: Glandular Papilloma and Mixed Squamous Cell and Glandular Papilloma Is Distinct From Bronchiolar Adenoma [0.03%]
外周支气管乳头状瘤中的AKT1突变：腺性乳头状瘤和混合的鳞状细胞与腺性乳头状瘤不同于支气管腺瘤
Eiichi Sasaki,Katsuhiro Masago,Shiro Fujita et al.
Eiichi Sasaki et al.
Glandular papilloma (GP) and mixed squamous cell and glandular papilloma (MP) are rare benign pulmonary tumors occurring in the bronchi. Bronchiolar adenoma (BA) was recently characterized as a pulmonary tumor exhibiting alveolar spread. Bo...
Clinicopathologic Significance of EGFR Mutation and HPV Infection in Sinonasal Squamous Cell Carcinoma [0.03%]
EGFR突变和HPV感染在副鼻窦鳞状细胞癌的临床病理意义
Takahiro Hongo,Hidetaka Yamamoto,Rina Jiromaru et al.
Takahiro Hongo et al.
Sinonasal squamous cell carcinoma (SNSCC) is sometimes associated with high-risk human papillomavirus (HR-HPV) infection and inverted sinonasal papilloma or oncocytic sinonasal papilloma. Frequent mutations of EGFR and KRAS are reported in ...
Optimal Criteria for G3 (Poorly Differentiated) Stage II Colon Cancer: Prospective Validation in a Randomized Controlled Study (SACURA Trial) [0.03%]
G3(分化差)II期结肠癌的最佳标准：在随机对照研究(SACURA试验)中的前瞻性验证
Hideki Ueno,Megumi Ishiguro,Eiji Nakatani et al.
Hideki Ueno et al.
Grade 3 (G3, poorly differentiated) is an important treatment-decision factor in stage II colon cancer, but no unified diagnostic criteria are established. According to previous studies, an intratumoural poorly differentiated area with no g...
Randomized Controlled Trial
The American journal of surgical pathology. 2020 Dec;44(12):1685-1698. DOI:10.1097/PAS.0000000000001570 2020